Uphononongo lwalukukuphanda iziphumo zoncediso lwe-TB ekukhuleni kwamantshontsho eehagu asandul’ ukusezwa i-IUGR.
Iindlela
Ishumi elinesithandathu le-IUGR kunye ne-8 NBW (ubunzima bomzimba obuqhelekileyo) amantshontsho eehagu asandul’ ukusandul’ ukunyulwa, alunyulwa ngosuku lwe-7 kwaye ondliwe izidlo ezisisiseko zobisi (i-NBW kunye neqela le-IUGR) okanye izidlo ezisisiseko zongezwa nge-0.1% ye-tributyrin (iqela le-IT, iihagu ze-IUGR ezityiswa nge-tributyrin) de kube usuku lwama-21 (n = 8).Ubunzima bomzimba wamantshontsho eehagu ngomhla we-0, 7, 10, 14, 17, no-20 babulinganiswa.Umsebenzi we-enzyme yokugaya, i-intestinal morphology, amanqanaba e-immunoglobulin kunye ne-gene expression ye-IgG, i-FcRn kunye ne-GPR41 emathunjini amancinci ahlalutywa.
Iziphumo
Ubunzima bomzimba weengulube kwi-IUGR kunye neqela le-IT lalifana, kwaye zombini zingaphantsi kweqela le-NBW kwiintsuku ze-10 kunye ne-14. Nangona kunjalo, emva komhla we-17, iqela le-IT libonise ukuphucula (P<0.05) ubunzima bomzimba xa kuthelekiswa nelo qela le-IUGR.Iingulube zanikelwa ngomhla we-21. Xa kuthelekiswa neengulube ze-NBW, i-IUGR iphazamise ukuphuhliswa kwamalungu omzimba kunye namathumbu amancinci, iphazamise i-intestinal villus morphology, iyancipha (P<0.05) uninzi lwemisebenzi evavanyiweyo ye-enzyme yokugaya intestinal, yehla (P<0.05) i-ileal sigA kunye ne-IgG amanqanaba, kunye ne-down-regulated (P<0.05) i-intestinal IgG kunye ne-GPR41 intetho.Amantshontsho eehagu kwiqela le-IT abonise uphuhliso olungcono (P<0.05) i-spleen kunye namathumbu amancinci, ukuphuculwa kwe-intestinal villus morphology, kwanda (P< 0.05) indawo ze-intestinal villus surface, eziphuculweyo (P<0.05) imisebenzi ye-enzyme yokugaya, kunye ne-up-regulated (P<0.05) intetho ye-IgG kunye ne-GPR41 mRNA xa kuthelekiswa nezo zeqela le-IUGR.
Izigqibo
Ukongezwa kwe-TB kuphucula ukukhula kunye nokugaya kwamathumbu kunye nemisebenzi yokuthintela kwiihagu ze-IUGR ngexesha lokuncancisa.
Funda ngakumbi malunga ne-tirbutyrin
| Ifomu: | Umgubo | Umbala: | Mhlophe Ukuya Kumhlophe |
|---|---|---|---|
| Isithako: | I-Tributyrin | Ivumba: | Ayinavumba |
| Ipropati: | I-Bypass Isisu | Umsebenzi: | UKhuthazo lokuKhula, i-Anti-bacteria |
| Ugxininiso: | 60% | Umthwali: | Silika |
| Inombolo yeCAS: | 60-01-5 | ||
| Ukukhanya okuphezulu: | I-Tributyrin 60% ye-Short Chain Fatty Acids, Anti Stress Ikhonkco elifutshane Fatty Acids, Feed Additive Short Chain Fatty Acids | ||
ISilica Carrier iTyayini emfutshane eFatty Acid Feed Additive Tributyrin 60% Ubuncinci kwiAqua
Igama leMveliso:Ding Su E60 (Tributyrin 60%)
Ifomula yemolekyuli:C15H26O6 Ubunzima bemolekyuli: 302.36
Ukuhlelwa kweMveliso:Isondlo Sokongeza
Inkcazo:Mhlophe ukuya kwiPowder emhlophe.Ukuqukuqela okuhle.Isimahla kwi-Typical Butyric Rancid Ivumba.
Umthamo kg/mt feed
| Ihagu | Aqua |
| 0.5-2.0 | 1.5-2.0 |
Umqulu:25kg ingxowa inethi.
Ugcino:Itywinwe Ngokungqingqwa.Kuphephe Ukutyhileka kubumanzi.
Ukuphelelwa lixesha:Iminyaka emibini ukususela kumhla wemveliso.
Ixesha lokuposa: Jun-30-2022