Guanylacetic acid, tseem hu ua guanylacetic acid, yog ib qho amino acid analogue tsim los ntawm glycine thiab L-lysine.

Guanylacetic acid tuaj yeem tsim cov creatine nyob rau hauv catalysis ntawm enzymes thiab tsuas yog qhov yuav tsum tau ua ua ntej rau kev sib txuas ntawm creatine.Creatine tau lees paub tias yog lub zog tsis muaj zog, thiab nws txoj haujlwm tseem ceeb yog tsim phosphorylated creatine nyob rau hauv qhov kev txiav txim ntawm creatine kinase.

Koom nrog adenosine mus txawv tebchawshosphate (ATP) lub voj voog.Thaum ATP lub zog tsis txaus, phosphocreatine sai hloov cov phosphate pawg mus rau adenosine diphosphate los ntawm creatine kinase thiab hloov nws rov qab mus rau adenosine triphosphate.

 

Daim ntawv thov hauv ruminants:

Ntxiv 0.12%, 0.08%, thiab 0.04% guanylacetic acid rau kev noj haus ntawm 120 barn pub Tan yaj uas hnyav txog 20 kilograms, raws li, qhia tau hais tias qhov sib ntxiv ntawm 0.12% thiab 0.08% guanylacetic acid ua rau muaj kev nce ntxiv hauv ib hnub, cov roj intramuscular, thiab cov ntsiab lus protein, thiab txo qis carcass rog cov ntsiab lus.

 

Ntxiv 0.08%Guanylacetic acidnce net nqaij feem pua ​​​​ntawm 9.77%.Los ntawm kev siv nyob rau hauv vitro gas ntau lawm txoj kev, cov nyhuv ntawm kev ntxiv ntau theem ntawm guanylacetic acid nyob rau hauv lub rumen ntawm nyuj daj tau kawm.Nws tau pom tias qhov sib ntxiv ntawm 0.4% guanylacetic acid ua rau muaj roj ntau ntxiv, thiab cov concentration ntawm ammonia nitrogen ua ntej nce thiab tom qab ntawd txo qis.

Yog li ntawd, nws tuaj yeem suav hais tias ntxiv guanylacetic acid rau txhua hnub pub tuaj yeem txhim kho rumen sab hauv ib puag ncig thiab fermentation hom ntawm nyuj daj.

Kev siv rau hauv cov nqaij qaib:

Ntxiv 800 mg / kg, 1600 mg / kg, 4000 mg / kg, thiab 8000 mg / kg ntawm guanylacetic acid rau kev pub noj txhua hnub ntawm broilers pom tau tias ntxiv 800-4000 mg / kg ntawm guanylacetic acid rau qhov pub tau nce qhov hnyav txhua hnub. nce ntawm broilers, txo qhov pub rau qhov hnyav piv ntawm broilers ntawm 22-42 hnub ntawm hnub nyoog.Ntxiv 8000 mg / kg ntawm guanylacetic acid txhim kho cov ntshav biochemical ntsuas xws li urea nitrogen, cov ntsuas ntshav niaj hnub, thiab tag nrho cov bilirubin Tsis muaj kev cuam tshuam tseem ceeb ntawm lub cev tseem ceeb, qhia tias ntxiv 8000 mg / kg ntawm guanylacetic acid rau noj txhua hnub ntawm broilers. yog tolerable.

Ntxiv 200 mg / kg, 400 mg / kg, 600 mg / kg, thiab 800 mg / kg ntawm guanylacetic acid rau broiler pub pom tias muaj qhov nce ntxiv ntawm qhov hnyav nruab nrab txhua hnub piv rau pawg tswj hwm.Cov txiaj ntsig zoo tshaj plaws tau ua tiav thaum qhov sib ntxiv yog 600 thiab 800 mg / kg.

Txhawm rau kawm txog cov txiaj ntsig ntawm guanylacetic acid ntawm cov phev zoo hauv roosters, 20 28 lub lis piam qub roosters raug xaiv los noj cov zaub mov uas muaj 0%, 0.06%, 0.12%, thiab 0.18% guanylacetic acid.Cov kev tshawb fawb tau pom tias ntxiv 0.12% guanylacetic acid rau cov khoom noj muaj txiaj ntsig ntau ntxiv rau cov phev, phev concentration, thiab cov phev ua haujlwm hauv roosters, qhia tias ntxiv guanylacetic acid rau kev noj haus tuaj yeem txhim kho cov phev zoo.Ntxiv 0.0314%, 0.0628%, 0.0942%, thiab 0.1256% guanylacetic acid rau kev pub noj txhua hnub ntawm broilers, thiab teem ob pawg tswj hwm (tswj pab pawg 1 yog cov nroj tsuag noj tsis muaj tshuaj ntxiv, thiab tswj pawg 2 yog pub nrog noj ntses ntxiv).Cov saum toj no rau pawg ntawm cov khoom noj txhua hnub muaj tib theem ntawm lub zog thiab cov zaub mov.

Cov txiaj ntsig kev sim qhia tau hais tias qhov hnyav nce ntawm plaub pawg nrog guanylacetic acid ntxiv thiab tswj pawg 2 yog siab dua li cov tswj pawg 1, Pawg tswj 2 muaj qhov zoo tshaj qhov hnyav nce, ua raws li 0.0942% guanylacetic acid pawg;Pawg tswj 2 muaj cov khoom zoo tshaj plaws rau qhov hnyav piv, ua raws li 0.1256% guanylacetic acid pawg.

Kev siv rau hauv cov nqaij qaib:

Ntxiv 800 mg / kg, 1600 mg / kg, 4000 mg / kg, thiab 8000 mg / kg ntawmGuanylacetic acidrau kev pub noj txhua hnub ntawm broilers pom tau tias ntxiv 800-4000 mg / kg ntawm guanylacetic acid rau qhov pub tau nce qhov hnyav txhua hnub ntawm broilers, txo qhov pub rau qhov hnyav piv ntawm broilers ntawm 22-42 hnub ntawm hnub nyoog.Ntxiv 8000 mg / kg ntawm guanylacetic acid txhim kho cov ntshav biochemical ntsuas xws li urea nitrogen, cov ntsuas ntshav niaj hnub, thiab tag nrho cov bilirubin Tsis muaj kev cuam tshuam tseem ceeb ntawm lub cev tseem ceeb, qhia tias ntxiv 8000 mg / kg ntawm guanylacetic acid rau noj txhua hnub ntawm broilers. yog tolerable.Ntxiv 200 mg / kg, 400 mg / kg, 600 mg / kg, thiab 800 mg / kg ntawm guanylacetic acid rau broiler pub pom tias muaj qhov nce ntxiv ntawm qhov hnyav nruab nrab txhua hnub piv rau pawg tswj hwm.Cov txiaj ntsig zoo tshaj plaws tau ua tiav thaum qhov sib ntxiv yog 600 thiab 800 mg / kg.

Txhawm rau kawm txog cov txiaj ntsig ntawm guanylacetic acid ntawm cov phev zoo hauv roosters, 20 28 lub lis piam qub roosters raug xaiv los noj cov zaub mov uas muaj 0%, 0.06%, 0.12%, thiab 0.18% guanylacetic acid.Cov kev tshawb fawb tau pom tias ntxiv 0.12% guanylacetic acid rau cov khoom noj muaj txiaj ntsig ntau ntxiv rau cov phev, phev concentration, thiab cov phev ua haujlwm hauv roosters, qhia tias ntxiv guanylacetic acid rau kev noj haus tuaj yeem txhim kho cov phev zoo.Ntxiv 0.0314%, 0.0628%, 0.0942%, thiab 0.1256% guanylacetic acid rau kev pub noj txhua hnub ntawm broilers, thiab teem ob pawg tswj hwm (tswj pab pawg 1 yog cov nroj tsuag noj tsis muaj tshuaj ntxiv, thiab tswj pawg 2 yog pub nrog noj ntses ntxiv).Cov saum toj no rau pawg ntawm cov khoom noj txhua hnub muaj tib theem ntawm lub zog thiab cov zaub mov.Cov txiaj ntsig kev sim qhia tau hais tias qhov hnyav nce ntawm plaub pawg nrog guanylacetic acid ntxiv thiab tswj pawg 2 yog siab dua cov tswj pawg 1, Pawg tswj 2 muaj qhov hnyav tshaj qhov hnyav, ua raws li 0.0942%.Guanylacetic acidpab pawg;Pawg tswj 2 muaj cov khoom zoo tshaj plaws rau qhov hnyav piv, ua raws li 0.1256% guanylacetic acid pawg.