Guanylacetic asidhi, inozivikanwawo se guanylacetic acid, inonzi amino acid analogue inoumbwa kubva kuglycine uye L-lysine.

Guanylacetic acid inogona kugadzira creatine pasi pe catalysis yema enzymes uye ndiyo chete inodiwa pakugadzirwa kwe creatine.Creatine inozivikanwa sesimba rekuchengetedza simba, uye basa rayo guru nderekugadzira phosphorylated creatine pasi pechiito che creatine kinase.

Tora chikamu murwendo rweadenosinehosphate (ATP) kutenderera.Kana simba reATP risina kukwana, phosphocreatine inokurumidza kutamisa boka rephosphate kuenda kuadenosine diphosphate kuburikidza necreatine kinase uye inoridzosera kuadenosine triphosphate.

 

Kushandiswa mune ruminants:

Kuwedzera 0.12%, 0.08%, uye 0.04% guanylacetic acid pakudya kwe120 barn yakadyiswa Tan makwai anorema anenge makirogiramu makumi maviri, zvichiteerana, kwakaratidza kuti kuwedzera kwe0.12% uye 0.08% guanylacetic acid zvakanyanya kuwedzera zuva nezuva uremu, uye intramuscular mafuta. protein yemukati, uye yakaderera zvakanyanya chitunha chemafuta emukati.

 

Kuwedzera kwe0.08%guanylacetic asidhiyakawedzera mambure enyama muzana ne9.77%.Nekushandisa in vitro gasi nzira yekugadzira gasi, mhedzisiro yekuwedzera mazinga akasiyana e guanylacetic acid pane rumen yeyero mombe yakadzidzwa.Zvakaonekwa kuti kuwedzera kwe0.4% guanylacetic acid zvakanyanya kuwedzera kugadzirwa kwegasi, uye kusanganiswa kweammonia nitrogen kwakatanga kuwedzera ndokuzoderera.

Naizvozvo, zvinogona kutaurwa kuti kuwedzera guanylacetic acid kukudya kwemazuva ese kunogona kuvandudza rumen yemukati nharaunda uye kuvirisa maitiro emombe yeyero.

Kushandisa muhuku:

Kuwedzera 800 mg/kg, 1600 mg/kg, 4000 mg/kg, uye 8000 mg/kg yeguanylacetic acid pakudya kwemazuva ese kwebroilers kwakaratidza kuti kuwedzera 800-4000 mg/kg ye guanylacetic acid kuchikafu kwakawedzera huremu hwezuva nezuva. Kuwedzera kwebroilers, kuderedza huremu hwehuremu hwebroilers pamazuva 22-42 ezera.Kuwedzera 8000 mg/kg ye guanylacetic acid yakavandudza serum biochemical zviratidzo zvakadai seurea nitrogen, zviratidzo zveropa, uye bilirubin yose Pakanga pasina kukanganisa kukuru pazviratidzo zvenhengo huru, zvichiratidza kuti kuwedzera 8000 mg/kg ye guanylacetic acid kune kudya kwemazuva ose kwebroilers. zvinoshiviririka.

Kuwedzera 200 mg / kg, 400 mg / kg, 600 mg / kg, uye 800 mg / kg ye guanylacetic acid kune broiler feed yakaratidza kuwedzera kukuru kwevhareji yezuva nezuva kuwedzera kuenzaniswa neboka rinodzora.Mhedzisiro yakanakisa yakawanikwa apo mazinga ekuwedzera aive 600 uye 800 mg / kg.

Kuti udzidze kushanda kwe guanylacetic acid pamhando yembeu mumajongwe, majongwe makumi maviri nesere evhiki akasarudzwa kuti adye chikafu chine 0%, 0.06%, 0.12%, uye 0.18% guanylacetic acid.Mhedzisiro yetsvagiridzo yakawana kuti kuwedzera 0.12% guanylacetic acid mukudya zvakanyanya kwakawedzera huwandu hwembeu, kusungwa kwembeu, uye kuita kwembeu mumajongwe, zvichiratidza kuti kuwedzera guanylacetic acid mukudya kunogona kunyatso kuvandudza kunaka kwembeu.Wedzera 0.0314%, 0.0628%, 0.0942%, uye 0.1256% guanylacetic acid kune chikafu chemazuva ese chebroilers, uye isa mapoka maviri ekutonga (control group 1 ndeyekudya kwezvirimwa pasina chero chinhu chakawedzerwa, uye boka rekutonga 2 chikafu chine hove kudya kwakawedzerwa).Mapoka matanhatu ari pamusoro pekudya kwemazuva ese ane mwero wakafanana wesimba nemaminerari.

Migumisiro yekuedza inoratidza kuti uremu hwehuwandu hwemapoka mana ane guanylacetic acid yakawedzerwa uye boka rekutonga 2 rakakwirira kudarika iro reboka rekutonga 1, Boka rekutonga 2 raiva nepamusoro pekugadzirisa uremu, rinoteverwa ne0.0942% guanylacetic acid boka;Boka rekutonga 2 raive nezvakanakisa zvehuremu reshiyo, richiteverwa ne0.1256% guanylacetic acid boka.

Kushandisa muhuku:

Kuwedzera 800 mg/kg, 1600 mg/kg, 4000 mg/kg, uye 8000 mg/kgguanylacetic asidhikuzvokudya zvezuva nezuva zvebroilers kwakaratidza kuti kuwedzera 800-4000 mg/kg ye guanylacetic acid kuzvokudya zvakanyanya kuwedzera kuwedzera kwezuva nezuva kwebroilers, kuderedza kudya kune uremu hwehuwandu hwemabroilers pamazuva 22-42 ekuberekwa.Kuwedzera 8000 mg/kg ye guanylacetic acid yakavandudza serum biochemical zviratidzo zvakadai seurea nitrogen, zviratidzo zveropa, uye bilirubin yose Pakanga pasina kukanganisa kukuru pazviratidzo zvenhengo huru, zvichiratidza kuti kuwedzera 8000 mg/kg ye guanylacetic acid kune kudya kwemazuva ose kwebroilers. zvinoshiviririka.Kuwedzera 200 mg / kg, 400 mg / kg, 600 mg / kg, uye 800 mg / kg ye guanylacetic acid kune broiler feed yakaratidza kuwedzera kukuru kwevhareji yezuva nezuva kuwedzera kuenzaniswa neboka rinodzora.Mhedzisiro yakanakisa yakawanikwa apo mazinga ekuwedzera aive 600 uye 800 mg / kg.

Kuti udzidze kushanda kwe guanylacetic acid pamhando yembeu mumajongwe, majongwe makumi maviri nesere evhiki akasarudzwa kuti adye chikafu chine 0%, 0.06%, 0.12%, uye 0.18% guanylacetic acid.Mhedzisiro yetsvagiridzo yakawana kuti kuwedzera 0.12% guanylacetic acid mukudya zvakanyanya kwakawedzera huwandu hwembeu, kusungwa kwembeu, uye kuita kwembeu mumajongwe, zvichiratidza kuti kuwedzera guanylacetic acid mukudya kunogona kunyatso kuvandudza kunaka kwembeu.Wedzera 0.0314%, 0.0628%, 0.0942%, uye 0.1256% guanylacetic acid kune chikafu chemazuva ese chebroilers, uye isa mapoka maviri ekutonga (control group 1 ndeyekudya kwezvirimwa pasina chero chinhu chakawedzerwa, uye boka rekutonga 2 chikafu chine hove kudya kwakawedzerwa).Mapoka matanhatu ari pamusoro pekudya kwemazuva ese ane mwero wakafanana wesimba nemaminerari.Mhedzisiro yekuedza inoratidza kuti huremu hwehuwandu hwemapoka mana ane guanylacetic asidhi yakawedzerwa uye kudzora boka 2 yakakwirira kupfuura yeboka rekutonga 1, Boka rekutonga 2 raive neakanakisa uremu mhedzisiro, ichiteverwa ne0.0942%guanylacetic asidhigroup;Boka rekutonga 2 raive nezvakanakisa zvehuremu reshiyo, richiteverwa ne0.1256% guanylacetic acid boka.