I-Tributyrin ikhiqizwa inkampani ye-Efine besekelwe ezicini zomzimba kanye nokulawulwa kokudla okunempilo kocwaningo lobuchwepheshe be-mucosa emathunjini yohlobo olusha lwemikhiqizo yokunakekelwa kwempilo yezilwane, kungagcwalisa ngokushesha umsoco wesilwane samathumbu, kukhuthaze ukuthuthukiswa nokuvuthwa kwe-mucosa yamathumbu, ukulungisa zonke izinhlobo zokucindezeleka okubangelwa ukulimala kwe-mucosa emathunjini, ukuvikela impilo yamathumbu, ukuqinisa umsebenzi wokugaya kwamathumbu kanye nokumuncwa, Kungavimbela ngempumelelo i-necrotizing enteritis futhi kuthuthukise ukusebenza kokukhiqizwa kwemfuyo nezinkukhu.

Indlela yokusebenza ye-butyric acid

Ama-acid amaningi anamafutha adingwa imfuyo nezinkukhu angatholakala ekudleni (okuphakelayo), kodwa amanye ama-acid e-short-chain fatty (njenge-butyric acid) awatholakali ngokuvamile ekudleni.I-short-chain fatty acids, ikakhulukazi i-butyric acid, idlala indima ebalulekile ekugcineni impilo yamathumbu emfuyo nezinkukhu, kuhlanganise:

1.I-Butyric acid ingumthombo wamandla osheshayo wokulungisa ukulimala kwamathumbu emfuyo nezinkukhu, engabola ngokushesha futhi ikhulule amandla, ikhuthaze ukukhula kolwelwesi lwe-chorionic, futhi ithuthukise ukusebenza komgoqo womzimba.

2.I-Butyric acid inganciphisa okuqukethwe komoyampilo emathunjini, ivimbele ukukhiqizwa kwamagciwane ayingozi adla umoya-mpilo, futhi ikhuthaze ukwanda kwamabhaktheriya anenzuzo njenge-lactic acid bacteria.

I-3.I-Butyric acid ingenza kusebenze amangqamuzana esignali asebenzayo amangqamuzana okuzivikela emathunjini futhi athuthukise ukuvikeleka kwe-mucosal yamathumbu emathunjini.

Imithombo nokuqhathaniswa kwe-butyric acid ekuphakeleni

Inqubo ye-metabolic ye-butyric acid ezilwaneni

Ukusebenza nezici

1.Njengoba uphethiloli oyinhloko wokuphefumula wamangqamuzana e-epithelial emathunjini, anganikeza ngokushesha amandla emangqamuzaneni e-epithelial emathunjini, akhuthaze ngokuphumelelayo ukukhula kwamangqamuzana e-mucosal emathunjini, abambe iqhaza ekugcinweni nasekulungisweni kwe-intestinal mucosa, nokugcina ubuqotho nokusebenza kwamaseli e-mucosal emathunjini.

2.Ukuphakama kwe-intestinal villus kuye kwanda,yehla ukujula kwe-crypt , ngconoisilinganiso sobude be-intestinal villus kuya ekujuleni kwe-crypt , futhingconoukwakheka kwe-morphological yamathumbu amancane.

3.Yehlisa i-pH yamathumbu, ivimbele ukukhula kwamagciwane e-pathogenic anjenge-Escherichia coli, i-Salmonella ne-Clostridium perfringens, ikhuthaze ukwanda kwamagciwane azuzisayo we-lactic acid bacteria, ilawule ibhalansi ye-microecological yamathumbu emfuyo nezinkukhu.

4.Khuthaza ukukhiqizwa kwama-antibodies kanye nokwanda kwamangqamuzana omzimba we-mucosa yamathumbu, kuthuthukise i-anti-stress kanye namandla okuzivikela emfuyo nezinkukhu, ukunciphisa ukuvela kokuvuvukala kwamathumbu nezinye izifo..

Isithombe 1Imithelela ye-triglyceride ne-Coated sodium butyrate ekuzuzeni kwansuku zonke kwama-broiler anezimpaphe ezimhlophe

Imiphumela yabonisa ukuthi uma kuqhathaniswa neqembu lokulawula, inzuzo yansuku zonke yama-broilers anezimpaphe ezimhlophe yande kakhulu ngokungezai-tributyrin, futhi umphumela wawungcono kuneqembu le-sodium butyrate ehlanganisiwe

Isithombe 2 Imiphumela ye-triglyceride ne-coated sodium butyrate ku-microflora yamathumbu ezinkukhu

Imiphumela ibonise ukuthi uma kuqhathaniswa neqembu lokulawula, ingezaI-Tributyrin inganciphisa kakhulu inani le-escherichia coli emathunjini enkukhu, futhi yandise ngokuphawulekayo inani lamabhaktheriya e-lactic acid, futhi umphumela wawungcono kuneqembu le-sodium butyrate ehlanganisiwe.

Imithelela ye-triglyceride ne-sodium butyrate ekukhuleni kanye nezinga Lohudo lwe-Piglet

Imiphumela yabonisa ukuthi, ngokufana nemiphumela yemithi elwa namagciwane, i-triglyceride ingakhuphula ngokuphawulekayo inzuzo yansuku zonke yamachwane ngo-11% ~ 14%, yehlise isilinganiso sokudla nenyama ngo-0.13 ~ 0.15, futhi yehlise kakhulu izinga lokuhuda kwamaphuphu, okuyinto yayingcono kakhulu kuneqembu le-sodium butyrate.

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