Nyob rau hauv xyoo tas los no, ntau thiab ntau "cov khoom xyaw" tau tshwm sim hauv kev lag luam tu tawv nqaij.Lawv tsis mloog cov lus tshaj tawm thiab kev zoo nkauj bloggers ' cog nyom ntawm lub siab nyiam, tab sis kawm thiab nkag siab cov khoom xyaw zoo ntawm cov khoom tu tawv nqaij los ntawm lawv tus kheej, thiaj li xaiv cov khoom tu tawv nqaij kom haum rau lawv.

Nrog rau kev sib tw hnyav zuj zus ntawm cov hom kev tu tawv nqaij, ntau thiab ntau lub npe tau nrhiav "cov khoom xyaw ntxiv" rau "cov khoom xyaw muaj txiaj ntsig".Cov khoom xyaw ntawm cov tawv nqaij txhawb nqa los ntawm kev siv tshuab dub yog ntau thiab nrov dua, tsim ib qho xwm txheej uas "thawj cov khoom siv sab nrauv saib cov khoom xyaw, thiab cov khoom noj khoom haus laus saib xyuas technology".

Ua tib zoo saib xyuas cov khoom tshiab ntawm cov khoom lag luam hauv tsev thiab txawv teb chaws, thiab pom tias lub taub hau hom no tau nrawm rau kev kho dua tshiab ntawm cov khoom siv raw thiab thev naus laus zis, kom cov khoom tshiab tuaj yeem nyiam cov neeg siv khoom ntau dua, thiab cov cuab yeej tshiab tuaj yeem ua rau kev lag luam nkag mus rau txoj kev tshiab. .Qhov nce ntawm kev tshawb fawb thiab thev naus laus zis tog yog qhov tseeb ntawm kev sib zog ua kom muaj kev sib haum xeeb rau cov kws kho tshuaj pleev ib ce.

Daim ntawv tshaj tawm txog 2025 txog kev siv science thiab thev naus laus zis hauv kev lag luam kev zoo nkauj qhia tau hais tias kev sib koom ua ke ntawm kev zoo nkauj thiab thev naus laus zis tau txhim kho nyob rau hauv qhov tob, thiab cov cuab yeej siv thev naus laus zis raws li kev tshawb fawb txog roj ntsha tseem yuav pab R & D thiab tsim cov tshiab tshiab. cov khoom zoo nkauj.Kev lag luam zoo nkauj tau qhib los ntawm kev tshawb fawb thiab thev naus laus zis yuav ua rau muaj kev tawg, thiab kev lag luam nplai yuav ncav cuag li 1 trillion yuan los ntawm 2025.

 

Kev tshawb fawb thiab kev loj hlob ntawm nano kws tshuaj npaj tau dhau los ua cov kev taw qhia tseem ceeb ntawm kev kho mob thoob ntiaj teb tam sim no thiab cov kws kho mob hauv zej zog, thiab kev siv cov qauv tshiab ntawm liposomes thiab vesiclespharmaceutical npaj thev naus laus zis xws li nano carrier thev naus laus zis hauv cov tshuaj pleev ib ce ua haujlwm tau txhawb thiab txhawb nqa los ntawm lub xeev. .

Vim hais tias tib neeg epidermis yog ib qho nyuaj rau nkag mus rau hauv, khoom noj khoom haus tsis yooj yim mus txog rau hauv lub tob txheej ntawm daim tawv nqaij, uas zoo heev rau kev siv cov nyhuv ntawm cov khoom siv tu tawv nqaij.Nanocarrier thev naus laus zis tau tshwm sim raws li lub sijhawm xav tau, feem ntau yog daws cov teeb meem ntawm kev xa khoom, tshuaj qeeb-tso, transdermal absorption thiab lwm yam.Cov nanocarriers uas nquag siv muaj xws li liposomes, hydrogel carriers, micelles, microcapsules, kua siv lead ua tshuab, supramolecules, thiab lwm yam.

Kev siv cov nanocarriers kom xa cov khoom siv kev saib xyuas ntawm daim tawv nqaij mus rau hauv cov chaw tu tawv nqaij lub hom phiaj thiab cov hlwb los ntawm cov tawv nqaij cov hom phiaj xa tawm, qeeb-tso thiab kav ntev, zoo daws cov kev lag luam uas muaj teeb meem ntawm kev siv tshuaj pleev ib ce uas nyuaj rau nqus los ntawm daim tawv nqaij.Nanocarriers kuj muaj lub luag haujlwm ntawm kev txhim kho cov solubility thiab dej dispersibility ntawm cov khoom xyaw ua haujlwm ntawm cov tshuaj pleev ib ce insoluble, txhim kho kev ruaj ntseg ntawm lub teeb rhiab thiab kub rhiab cov khoom xyaw, thiab txhim kho kev sib raug zoo ntawm cov khoom xyaw ua haujlwm.

Thaum ntxov li xyoo 1965, cov kws tshawb fawb Askiv Bangham thiab Standish tau pom tias phospholipids tuaj yeem ua rau lub cev bilayer vesicles (micelle) hauv dej los ntawm electron microscopy, thiab hu lawv liposomes.Qhov no tau dhau los ua ib qho kev tshawb pom loj hauv kev lag luam tshuaj hauv xyoo pua 20th.

Lub Pearl ntawm lub crown ntawm nanocarriers - liposomes

Txij li thaum cov qauv ntawm cov plasma cov ntaub so ntswg tseem yog phospholipid bilayer membrane, liposomes muaj cov qauv zoo sib xws rau cov hlwb, yog li lawv muaj biocompatibility zoo, yog li lawv kuj hu ua "artificial biofilm".Liposomes siv qhov kev sib raug zoo no kom ua tiav cov hom phiaj lossis kev xa tshuaj zoo.Cov liposomes zoo tshaj plaws yuav tsum muaj qhov zoo histocompatibility, tsis muaj tshuaj lom, tsim cov tshuaj encapsulation thiab tso tawm muaj peev xwm.

Raws li lub npe implies, lub ntsiab ntawm liposomes yog "lipids".Feem ntau cov liposomes feem ntau yog ua los ntawm phospholipids thiab cov roj cholesterol, uas yog cov tshuaj endogenous uas muaj nyob hauv cov kab mob, muaj kev sib raug zoo nrog cov ntaub so ntswg thiab tsis muaj kev tiv thaiv kab mob.

Customized raw khoom tswv yim rau liposomes

Lub npe lag luam ntawm cov khoom siv raw: tiv thaiv kev laus liposome

Compound encapsulation tswvyim: liposome + retinol + astaxanthin + coenzyme Q10

Raw khoom ua tau zoo: compact thiab wrinkle resistant

Kev siv tau pom zoo: 5% - 10%

Cov khoom siv: Essence dej, essence, lub ntsej muag daim npog qhov ncauj, gel, lotion, cream