Eminyakeni yamuva nje, "amaqembu ezithako" ayanda kakhulu embonini yokunakekelwa kwesikhumba.Abasazilaleli izikhangiso kanye notshani obutshalwa ngubuhle ngokuthanda kwabo, kodwa bafunda futhi baqonde izithako ezisebenzayo zemikhiqizo yokunakekelwa kwesikhumba ngokwabo, ukuze bakhethe imikhiqizo yokunakekelwa kwesikhumba ebafanele.

Ngokuncintisana okushubile phakathi kwemikhiqizo yokunakekelwa kwesikhumba, imikhiqizo eminingi iphishekela "izithako eziningi" ukuze "izithako eziwusizo".Izithako zokunakekelwa kwesikhumba ezisekelwa ubuchwepheshe abamnyama ziya ngokuya zithandwa, zenza isimo sokuthi "i-primary ingredient party ibheka izithako, futhi i-party ingredient party ibheka ubuchwepheshe".

Naka imikhiqizo emisha yamakhanda asekhaya nakwamanye amazwe, futhi uthole ukuthi lezi zinhlobo zamakhanda zisheshisa ukuthuthukiswa kwezinto ezingavuthiwe nobuchwepheshe, ukuze imikhiqizo emisha ihehe abathengi abaningi, futhi ubuchwepheshe obusha bungaholela imboni ukuthi ingene ithrekhi entsha. .Ukukhuphuka kweqembu lesayensi nobuchwepheshe empeleni kuwuphawu lokubambelela okuqinile kwangaphakathi kwabasebenzi bezimonyo.

Umbiko wombono ka-2025 wokusetshenziswa kwesayensi nobuchwepheshe embonini yobuhle ubonisa ukuthi ukuhlanganiswa kobuhle nobuchwepheshe kukhula ngokujulile, futhi ubuchwepheshe obusezingeni eliphezulu obusekelwe kusayensi yezinto eziphilayo buzoqhubeka nokusiza i-R & D kanye nokukhiqizwa kwezinto ezintsha. imikhiqizo yobuhle.Imboni yobuhle enikwe amandla isayensi nobuchwepheshe izoletha ukuqhuma, futhi isikali semakethe sizofinyelela cishe ku-1 trillion yuan ngo-2025.

 

Ucwaningo nokuthuthukiswa kwamalungiselelo emithi ye-nano sekuyinkomba evamile yomphakathi wamanje wezokwelapha kanye nemithi yamazwe ngamazwe, futhi ukusetshenziswa kweSakhiwo esisha se-liposomes kanye nobuchwepheshe bokulungiselela i-vesiclespharmaceutical njengobuchwepheshe be-nano carrier ezimonyoni ezisebenzayo kuye kwakhuthazwa futhi kwasekelwa umbuso. .

Ngenxa yokuthi i-epidermis yomuntu inzima ukungena, ukudla okunomsoco kunzima ukufinyelela ungqimba olujulile lwesikhumba, okuthinta kakhulu umphumela wokusetshenziswa kwemikhiqizo yokunakekelwa kwesikhumba.Ubuchwepheshe be-Nanocarrier buvele njengoba izikhathi zidinga, ikakhulukazi ukuxazulula izinkinga zokulethwa okuhlosiwe, ukukhishwa kancane kwezidakamizwa, ukumuncwa kwe-transdermal nokunye.I-nanocarriers evame ukusetshenziswa ihlanganisa ama-liposomes, abathwali be-hydrogel, ama-micelles, ama-microcapsules, amasistimu e-crystal liquid, ama-supramolecules, njll.

Ukusetshenziswa kwe-nanocarriers ukuletha izithako ezisebenzayo zokunakekelwa kwesikhumba ezindaweni ezihlosiwe zokunakekelwa kwesikhumba kanye namaseli ngokulethwa okuhlosiwe kwesikhumba, ukukhishwa kancane kancane nokuhlala isikhathi eside, ukuxazulula ngempumelelo imboni inkinga evamile yezobuchwepheshe yezimonyo ezisebenzayo zendabuko okunzima ukuzithola ngesikhumba.I-Nanocarriers iphinde ibe nemisebenzi yokuthuthukisa ukunyibilika nokuhlakazeka kwamanzi kwezithako ezisebenzayo zezimonyo ezingancibiliki, ukuthuthukisa ukuzinza kwezithako ezizwela ukukhanya nokushisa okuzwelayo, kanye nokwenza ngcono ukuhambisana kwezithako ezisebenzayo.

Kusukela ngo-1965, izazi zaseBrithani u-Bangham no-Standish zathola ukuthi ama-phospholipid angakwazi ukwakha ama-bilayer vesicles (micelle) emanzini ngokusebenzisa i-electron microscopy, futhi aqamba ngokuthi ama-liposomes.Lokhu kwaba ngenye yezinto ezinkulu ezatholwa emkhakheni wezokwelapha ekhulwini lama-20.

Iparele kumqhele we-nanocarriers -- liposomes

Njengoba isakhiwo esiyisisekelo se-biological plasma membrane iphinde ibe ulwelwesi lwe-phospholipid bilayer, ama-liposomes anesakhiwo esifanayo namangqamuzana ezinto eziphilayo, ngakho anokubambisana okuhle kwe-biocompatibility, ngakho abizwa nangokuthi "i-biofilm yokufakelwa".Ama-Liposomes asebenzisa lokhu kuhambisana ukuze afinyelele ukulethwa kwezidakamizwa okuhlosiwe noma okuphumelelayo.Ama-liposomes afanelekile kufanele abe nokuhambisana okuhle kwe-histocompatibility, ubuthi obuphansi, i-encapsulation yezidakamizwa efanelekile kanye namandla okukhululwa.

Njengoba igama lisho, ingxenye eyinhloko ye-liposomes "lipids".Ama-liposomes ajwayeleke kakhulu enziwa ngama-phospholipids kanye ne-cholesterol, okuyizinto ezingapheli ezikhona ezintweni eziphilayo, ezihambisana kahle nezicubu futhi aziwona ama-immunogenic.

Isikimu sezinto ezingavuthiwe ezenziwe ngokwezifiso zama-liposomes

Igama lokuhweba lezinto ezingavuthiwe: ukuzivikela ngokumelene nokuguga kwe-liposome

I-Compound encapsulation scheme: i-liposome + retinol + i-astaxanthin + i-coenzyme Q10

Ukusebenza kahle kwempahla eluhlaza: kuhlangene futhi ukumelana nemibimbi

Ukusetshenziswa okunconyiwe: 5% - 10%

Imikhiqizo esebenzayo: Amanzi e-essence, i-essence, imaski yobuso, ijeli, i-lotion, ukhilimu