DMPT, CAS NO.: 4337-33-1.Ka ʻoi aʻemea hoihoi waii kēia manawa!

DMPTʻike ʻia ʻo dimethyl-β-propiothetin, aia i ka limu a me nā mea kanu halophytic kiʻekiʻe.He hopena koʻikoʻi ka DMPT i ka metabolism meaʻai o nā mammals, moa, a me nā holoholona wai (iʻa a me ka ʻōpae).ʻO DMPT ka waiwai me ka hopena lure ikaika loa i nā holoholona wai ma waena o nā pūhui i ʻike ʻia i loko o nā pūʻulu (CH) a me S.

1. Puna o DMPT

ʻO ka dimethyl sulfide (DMS) i hana ʻia e Polysipho - nia fastigata ka mea nuiDMPT, 'o ia hoʻi he methyl hāʻawi maikaʻi i loko o nā algae, a me ka mea hoʻoponopono osmotic nui o nā algae a me ka mea kanu mudflat Spartina angelica ʻo DMPT pū kekahi.'Oko'a ka ma'i'o o DMPT ma waena o nā 'ano limu like 'ole, a 'oko'a ka ma'i'o o ia 'ano limu i nā kau like 'ole.Hiki i ka DMPT ke hoʻolalelale i ka hānai ʻana a me ka ulu ʻana o nā iʻa wai hou.He ʻokoʻa ka hopena hoʻoulu ʻai o DMPT mai nā mea ʻē aʻe e like me ka L-amino acids a i ʻole nucleotides, a loaʻa iā ia ka hānai ʻana a me ka hoʻoulu ʻana i ka ulu ʻana ma kahi kokoke i nā holoholona wai āpau.

2.1 ʻO nā Ligands kūpono e like me nā mea ʻono

ʻO ka noiʻi ʻana e pili ana i nā mea hoʻokipa i loko o nā ʻāpana kemika iʻa hiki ke launa pū me (CH) S-pūʻulu paʻa.Mai nā hopena hoʻokolohua hoʻokolohua e loaʻa nei, hiki ke ʻike ʻia he mau mea ʻono ka iʻa e hiki ke launa pū me nā pūhui kaumaha molekala haʻahaʻa i loaʻa (CH), N -, a me (CH2) 2S - pūʻulu.

2.2 Ma ke ʻano he mea hāʻawi methyl

ʻO nā hui (CH) a me S ma kaDMPTʻO ka mole ke kumu o nā pūʻulu methyl e pono ai no ka metabolism meaʻai holoholona.ʻElua ʻano methyltransferases (EC2.1.1.3 a me EC2.1.1.5) i loko o ke ake holoholona i hoʻohana ʻia e nā holoholona (CH) a me S.

Ua ʻike ʻia ka piʻi ʻana o ka nui o ka DMPT a me ka nui o ka hoʻokuʻu ʻana o DMS i loko o nā keʻena limu me ka piʻi ʻana o ka paʻakai i loko o ka moʻomeheu moʻomeheu o ka limu moʻomeheu (Hymenonas carterae).

DMPTua hoʻonui ʻia i loko o nā keʻena o nā phytoplankton he nui, nā algae, a me nā mollusks symbiotic e like me nā clams a me nā koʻa, a me nā kino krill a me nā iʻa.Iida et al.(1986) ua hōʻoia i ka hoʻopili maikaʻi ʻana o ka DMPT a me ka hana ʻana o DMS i nā iʻa me ka DMPT ma kā lākou ʻai, e hōʻike ana i ka laiki DMPT i nā holoholona mai ka maunu a komo i ke kino holoholona kanaka ma o ke kaulahao meaʻai i loko o nā kaiaola kai. .Hiki i nā algae ke synthesize i ka DMPT a hōʻiliʻili iā ia ma nā pae kiʻekiʻe (3-5 mmol/L) i loko o ke kino.ʻO ka DMPT i loko o nā iʻa a me nā mollusks kokoke i ko lākou mau pae i ka meaʻai, a ʻo ka neʻe ʻana o DMPT e hōʻike ana i ka emi ʻana o ke ʻano ma ke ʻano o nā algae (1 mmol/L), nā mollusks (0.1 mmol/L), a me nā iʻa (0.01 mmol/L. L).

ʻO ke kino kino oDMPTHana

I nā makahiki i hala iho nei, ua ʻike ʻia ka noiʻi he hopena hoʻoikaika ka DMPT i ka hana hānai a me ka ulu ʻana o nā iʻa kai a me ka wai hou, crustaceans, a me ka iʻa, hiki ke hoʻomaikaʻi i ko lākou anti stress a me ka hoʻoikaika kino, a hoʻohui i nā enzyme kī o ka hui haʻahaʻa haʻahaʻa methyl. i ka ai.Ke hoʻohana nei i ke akepaʻa o ke kai bream e like me ka mea hoʻokolohua a me nā pūhui like ʻole i loaʻa (CH) a me S - pūʻulu ma ke ʻano he substrates, ua ʻike ʻia ʻo E C.2.1.1.3 a me E ʻO ka hana enzyme ka mea kiʻekiʻe loa ke hoʻohana ʻia ʻo DMPT ma ke ʻano he substrate.

3. Nā hopena meaʻai o DMPT i nā holoholona wai

Ua hoʻohana ʻia nā pūʻulu olaola he iwakāluakūmālima haʻahaʻa me ka (CH) a me nā pūʻulu S no ka hana nahu a me nā hoʻokolohua electrophysiological ma ke kai a me nā iʻa wai maʻemaʻe.Ua ʻike ʻia ʻo ka DMPT ka hopena hoʻoikaika ikaika loa i ka hana nahu ʻana o nā ʻano iʻa ʻekolu, e like me ka tuna wai, ka carp, a me ka carp crucian ʻeleʻele (Carassius auratus cuviera).Ua hoʻoikaika nui ʻia ka hana hānai ʻana o ka unahi wai maoli (Pagrus major) a me nā unahi ʻelima (Seriola quinquera diata).

Hoʻohui i ka DMPT a me nā mea ʻē aʻe i loaʻa i ka sulfur ma kahi ʻano o 1.0mmol/L.i loko o nā meaʻai hoʻokolohua like ʻole, a hoʻololi i ka pūʻulu hoʻomalu me ka wai distilled e hana i nā hoʻokolohua pane hānai ʻana i ka crucian carp.Ua hōʻike nā hopena i nā hui mua ʻehā o nā hoʻokolohua, ua loaʻa i ka hui DMPT ka awelika o 126 kiʻekiʻe o nā alapine nahu ma mua o ka pūʻulu mana;Ma ka lua o ka hoʻokolohua 5-hui, ʻo ka hui DMPT he 262.6 mau manawa kiʻekiʻe ma mua o ka pūʻulu mana.I loko o kahi hoʻokolohua hoʻohālikelike me ka glutamine, ua ʻike ʻia ma kahi ʻano o 1.0mmol/L.