I-DMPT, INOMBOLO YECAS: 4337-33-1.Egqibeleleumtsalane wasemanziningoku!

I-DMPTeyaziwa ngokuba yi-dimethyl-β-propiothetin, ifumaneka ngokubanzi kwizityalo zolwandle kunye ne-halophytic ephezulu.I-DMPT inefuthe elikhuthazayo kwimetabolism yesondlo sezilwanyana ezincancisayo, iinkukhu, kunye nezilwanyana zasemanzini (intlanzi kunye ne-shrimp).I-DMPT yinto enefuthe elinamandla kwizilwanyana zasemanzini phakathi kwazo zonke iikhompawundi ezaziwayo eziqulathe (CH) kunye namaqela e-S.

1. Umthombo we-DMPT

I-dimethyl sulfide (DMS) eveliswe yiPolysipho - nia fastigata iphuma ikakhuluI-DMPT, ekwangumnikelo osebenzayo we-methyl kwi-algae, kunye nomlawuli oyintloko we-osmotic we-algae kunye nesityalo se-mudflat Spartina angelica nayo i-DMPT.Umxholo we-DMPT uyahluka phakathi kweentlobo ezahlukeneyo zokhula lwaselwandle, kwaye umxholo wohlobo olufanayo lwezityalo zaselwandle nazo ziyahluka ngamaxesha ahlukeneyo onyaka.I-DMPT inokukukhawulezisa kakhulu ukondla kunye nokukhula kweentlanzi ezahlukeneyo zamanzi acwengileyo.Impembelelo yokutya ye-DMPT ihluke kwezinye izinto ezifana ne-L-amino acids okanye i-nucleotides, kwaye inefuthe lokutya kunye nokukhuthaza ukukhula phantse kuzo zonke izilwanyana zasemanzini.

2.1 IiLigands ezisebenzayo njengezamkeli zokungcamla

Uphando kwi-receptors kwiintlanzi ze-sensory parts zekhemikhali ezinokusebenzisana (CH) S-amaqela ayikabhalwa.Ukususela kwiziphumo zovavanyo zokuziphatha ezikhoyo, kunokuhlalutya ukuba intlanzi ngokuqinisekileyo ine-taste receptors enokuthi idibanise ne-low molecular weight compounds equkethe (CH), N -, kunye (CH2) 2S - amaqela.

2.2 Njengomnikeli wemethyl

I (CH) kunye S-amaqela kwiI-DMPTI-molecule yimithombo yamaqela e-methyl afunekayo kwi-metabolism yesondlo sezilwanyana.Kukho iintlobo ezimbini ze-methyltransferases (EC2.1.1.3 kunye ne-EC2.1.1.5) kwisibindi sezilwanyana ezisetyenziswa zizilwanyana (CH) kunye ne-S.

Kwafunyaniswa ukuba ukuxinwa kwe-DMPT kunye nesantya sokukhutshwa kwe-DMS kwiiseli ze-seaweed zonyuka ngokunyuka kwetyuwa kwindawo yenkcubeko yolwandle olukhuliswe (Hymenonas carterae).

I-DMPTityetyiswe kwiiseli ezininzi zephytoplankton, algae, kunye nemollusk ehambelanayo efana neclams kunye neekorale, kunye nekrill kunye nemizimba yeentlanzi.Iida et al.(I-1986) iqinisekisile ukuba umxholo we-DMPT kunye nokuveliswa kwe-DMS kwiintlanzi zihambelana ngokufanelekileyo kunye nomxholo we-DMPT ekudleni kwazo, ebonisa ukuba irayisi ye-DMPT kwizilwanyana ivela kwi-bait kwaye ingena kumzimba wesilwanyana somntu ngokusebenzisa ikhonkco lokutya kwizinto eziphilayo zaselwandle. .I-algae inokwenza i-DMPT kwaye iqokelele kumanqanaba aphezulu (3-5 mmol / L) emzimbeni.I-DMPT kwiintlanzi kunye ne-mollusks isondele kumanqanaba abo ekutyeni, kwaye ukugxininiswa kwe-DMPT kubonisa ukuhla kokunciphisa umyalelo we-algae (1 mmol / L), i-mollusks (0.1 mmol / L), kunye nentlanzi (0.01 mmol / L).

IPhysiological Mechanism yeI-DMPTIsenzo

Kwiminyaka yakutshanje, uphando luye lwafumanisa ukuba i-DMPT inefuthe elikhuthazayo ekuziphatheni kokutya kunye nokukhula kweentlanzi zaselwandle kunye namanzi ahlambulukileyo, ii-crustaceans, kunye ne-shellfish, ezinokuphucula ukuxinezeleka kwazo kunye nokukwazi ukuzilolonga, kunye nokongeza i-enzymes eziphambili zeqela eliphantsi le-methyl. ekutyeni.Ukusebenzisa isibindi se-sea bream njengento yokuhlola kunye neentlobo ezahlukeneyo eziqukethe (CH) kunye ne-S - amaqela njengama-substrates, kwafunyaniswa ukuba i-E C.2.1.1.3 kunye ne-E Umsebenzi we-enzyme uphezulu xa i-DMPT isetyenziswa njenge-substrate.

3. Iziphumo zesondlo ze-DMPT kwizilwanyana zasemanzini

Amashumi amabini asezantsi eekhompawundi ezinobunzima bemolekyuli equlathe (CH) kunye namaqela e-S asetyenziselwe ukuziphatha okulumayo kunye novavanyo lwe-electrophysiological kumanzi olwandle kunye neentlanzi zamanzi acwengileyo.Kwafunyaniswa ukuba i-DMPT inefuthe elinamandla lokukhuthaza ukuziphatha okulumayo kweentlobo ezintathu zeentlanzi, kubandakanywa ityhuna yamanzi ahlambulukileyo, i-carp, kunye ne-black crucian carp (i-Carassius auratus cuviera).Ikwakhuthaze ngokubalulekileyo indlela yokutyisa amanzi olwandle ngokwenyani (iPagrus enkulu) kunye nezikali ezintlanu (Seriola quinquera diata).

Xuba i-DMPT kunye nezinye iikhompawundi ezinesulfure kuxinzelelo lwe-1.0mmol/L.kwizidlo ezahlukeneyo zovavanyo, kwaye endaweni yeqela lolawulo ngamanzi adityanisiweyo ukuqhuba iimvavanyo zempendulo yokondla kwi-crucian carp.Iziphumo zibonise ukuba kumaqela amane okuqala ovavanyo, iqela le-DMPT linomlinganiselo we-126 ephezulu yokuluma ngaphezu kweqela lokulawula;Kwiqela lesibini leqela le-5, iqela le-DMPT lalinamaxesha angama-262.6 aphezulu kuneqela lokulawula.Kuvavanyo oluthelekisayo ne-glutamine, kwafunyaniswa ukuba kuxinzelelo lwe-1.0mmol/L.