Lwm txoj hauv kev kho tshuaj tua kab mob yuav tsum tau ua vim qhov txwv tsis pub siv cov tshuaj no los ua kev txhawb nqa kev loj hlob hauv cov khoom noj tsiaj.Tributyrin zoo nkaus li ua lub luag haujlwm hauv kev txhim kho kev loj hlob ntawm npua, txawm hais tias muaj ntau yam kev ua tau zoo.

Txog tam sim no, tsawg heev paub txog nws cov teebmeem ntawm plab microbiota muaj pes tsawg leeg.Hauv txoj kev tshawb no, peb tau tshawb xyuas lub plab microbiota hloov pauv ntawm piglets tau txais, ntawm kev txiav, 0.2% tributyrin ntxiv rau lawv cov zaub mov basal.

Tributyrin pab pawg muaj peev xwm txhim kho lub zog metabolism thiab txo qhov muaj peev xwm rau cov metabolism hauv carbohydrate.Hauv kev xaus, peb cov txiaj ntsig tau qhia tias tributyrin tuaj yeem txhawb kev hloov pauv hauv lub plab microbial cov zej zog, uas tuaj yeem pab txhawb kev txhim kho tsiaj txhu tom qab weaning.

Qhov cuam tshuam ntawm Tributyrin ntawm Gut Microbiota Ua haujlwm cuam tshuam rau kev ua yeeb yam ntawm Weaning Piglets

Khoom Parameters

Tributyrin (tseem lub npe hu ua Glyceryl tributyrate; Glycerol tributyrate; Glycery tributyrate; propane-1,2,3-triyl tributanoate), yog ib hom luv luv saw fatty acid ester.

CAS Nr: 60-01-5

EINECS No.: 200-451-5

Cov roj formula: C15H26O6

PIB: 302.36

Qhov tsos: Nws yog dawb mus rau daj oily kua nrog me ntsis roj aroma.

Solubility: soluble nyob rau hauv ethanol, chloroform thiab ether, hardly soluble nyob rau hauv dej (0.010%).

Lub neej txee: 24 Lub Hlis

Pob: 25KG / Hnab

Cia: Muab ntim rau ntawm qhov chaw qhuav thiab qhov cua

Tributyrinyog triglyceride uas muaj peb butyrate molecules esterified rau glycerol, augments butyrate concentrations tom qab hydrolyzation los ntawm pancreatic lipases.

Cov yam ntxwv ntawm Tributyrin
Cov tiam tshiab ntawm butyrate-glycerol ester ntawm butyric acid.
100% bypass plab.
Xa butyric acids rau hauv cov hnyuv me, tsis tas yuav tsum tau coated.
Lawm yuav pom nyob rau hauv cov mis nyuj thiab zib mu.

Kev sib piv ntawm Tributyrin & Butyrate ntsev

nws ib nrab-lub neej ntawm butyric acid yog 6 feeb.Butyrate tsis yooj yim mus cuag lwm cov ntaub so ntswg thiab cov kabmob sab nraum txoj hnyuv uas tau tswj hwm hauv daim ntawv ntawm butyric acid lossis butyrate.Txawm li cas los xij, ib nrab-lub neej ntawm tributyrin yog 40min, thiab cov plasma concentration ntawm butyrate tuaj yeem khaws cia siab tshaj 0.1mM rau 0.5-4h los ntawm qhov ncauj. .

Mechanism & Nta

Lub Zog Muaj Zog

Raws li paub zoo, butyric acid yog cov roj ntsha luv luv uas yog lub zog tseem ceeb ntawm cov hnyuv epithelial hlwb.Ntau tshaj 70% ntawm lub zog rau kev loj hlob ntawm cov hnyuv epithelial hlwb yog muab los ntawm butyric acid.Txawm li cas los xij, tributyrin muab qhov siab tshaj plaws lub plab tso tawm butyric acid tus nqi piv nrog rau lwm cov khoom butyrate.

Kev tiv thaiv lub plab

►Tributyrin txhawb kev loj hlob thiab kev sib txawv ntawm cov hnyuv mucosal epithelial hlwb, kho cov mucosa puas, thiab nthuav dav thaj chaw rau nqus cov as-ham.

►Tributyrin txhawb kev nthuav qhia ntawm cov nqaij ntshiv nruj hauv plab, tswj cov kev sib txuas ntawm cov hlwb, tiv thaiv macromolecules xws li cov kab mob thiab cov co toxins nkag mus rau hauv lub cev, thiab tswj lub cev kev ua haujlwm ntawm lub plab.

►Tributyrin txhawb kev tso tawm ntawm mucin (Muc) thiab ntxiv dag zog rau cov kab mob hauv plab hnyuv ua haujlwm.

Ciaj sia nyob tus nqi txhim kho

Tributyrin tuaj yeem txhawb kev sib txuas ntawm hemoglobin, txhim kho lub peev xwm ntawm oxygen-nqa, ntxiv dag zog rau lub neej endogenous kev txhawb nqa, thiab nws tuaj yeem txhim kho kev ua haujlwm ntawm mitochondria thiab txhawb nqa cov synthesis ntawm ATP, cov khoom siv hluav taws xob uas ua rau lub neej ua haujlwm.thiaj li txhim kho cov ciaj sia taus los yog tsiaj txhu.

Anti-Inflammatory & Antibacteria

► Los ntawm inhibiting cov haujlwm ntawm NF-Kb, TNF-α thiab TLR, Tributyrin tuaj yeem txo qhov kev puas tsuaj.

►Tributyrin txhawb kev qhia ntawm endogenous tiv thaiv peptides, uas tuaj yeem tiv thaiv kab mob thiab kab mob dav dav.