Mekhoa e meng ea phekolo ea lithibela-mafu e ea hlokahala ka lebaka la thibelo ea tšebeliso ea meriana ena e le ba khothalletsang kholo tlhahisong ea lijo tsa liphoofolo.Tributyrin e bonahala e phetha karolo ea ho ntlafatsa ts'ebetso ea kholo ea likolobe, le hoja e na le mekhoa e fapaneng ea katleho.

Ho fihlela joale, ha ho tsejoe haholo ka litlamorao tsa eona ho sebopeho sa gut microbiota.Thutong ena, re ile ra etsa lipatlisiso ka liphetoho tsa mala a microbiota a likolobe tse amohelang, ha li khoesoa, 0.2% tributyrin e kenyellelitsoe lijong tsa bona tsa basal.

Sehlopha sa Tributyrin se na le monyetla o matlafalitsoeng oa metabolism ea matla le monyetla o fokotsehileng oa metabolism ea carbohydrate.Qetellong, liphetho tsa rona li bonts'itse hore tributyrin e ka khothaletsa liphetoho sechabeng sa likokoana-hloko tsa mala, tse ka kenyang letsoho ho ntlafatseng ts'ebetso ea liphoofolo ka mor'a ho khoesoa.

Litlamorao tsa Tributyrin ho Gut Microbiota Shifts e Amanang le Ts'ebetso ea Likolobe tse Amisoang.

Lihlahisoa tsa lihlahisoa

Tributyrin (hape e bitsoa Glyceryl tributyrate; Glycerol tributyrate; Glycery tributyrate; propane-1,2,3-triyl tributanoate), ke mofuta oa ketane e khutšoane ea mafura a acid ester.

CAS RN: 60-01-5

Nomoro ea EINECS: 200-451-5

Mokhoa: C15H26O6

FW: 302.36

Ponahalo: Ke mokelikeli o mafura o mosoeu ho isa ho o mosehla o nang le monko o mafura hanyane.

Sollubility: e qhibilihang ka har'a ethanol, chloroform le ether, ha e khone ho qhibiliha ka metsing (0.010%).

Shelf Life: Likhoeli tse 24

Pakete: 25KG / Mokotla

Polokelo: E koaletsoe libakeng tse omeletseng le tse nang le moea o kenang

Tributyrinke triglyceride e nang le limolek'hule tse tharo tsa butyrate esterified ho glycerol, e eketsa bongata ba butyrate ka mor'a hydrolyzation ka pancreatic lipases.

Litšobotsi tsa Tributyrin
Moloko o mocha oa butyrate-glycerol ester ea butyric acid.
100% bypass mala.
Ho fana ka li-butyric acid ka maleng a manyane, ha ho hlokahale hore li koaheloe.
Ka tlhaho e fumaneha lebeseng le maheng a linotsi.

Papiso Pakeng tsa Tributyrin & Butyrate Letsoai

Halofo ea bophelo ba asiti ea butyric ke metsotso e 6.Butyrate e thata ho fihlella lisele tse ling le litho tse ling tse ka ntle ho mala a tsamaisoang ka mokhoa oa butyric acid kapa butyrate.Leha ho le joalo halofo ea bophelo ea tributyrin ke 40min, 'me motsoako oa plasma oa butyrate o ka bolokoa ka holimo ho 0.1mM bakeng sa 0.5-4h ka molomo oa molomo. .

Mokhoa le Likarolo

Mofani oa Matla

Joalo ka ha ho tsebahala, asiti ea butyric ke acid e khuts'oane ea mafura eo e leng mohloli o ka sehloohong oa matla a lisele tsa epithelial tsa mala. Ho feta 70% ea matla bakeng sa kholo ea lisele tsa mala a epithelial a fanoa ke asiti ea butyric.Leha ho le joalo, tributyrin e fana ka boleng bo phahameng ka ho fetesisa bo lokollang butyric acid ha bo bapisoa le lihlahisoa tse ling tsa butyrate.

Tšireletso ea mala

►Tributyrin e khothalletsa ho ata le ho arohana ha lisele tsa mala a mala, ho lokisa mucosa e senyehileng, le ho atolosa sebaka se ka holimo bakeng sa ho monya limatlafatsi.

►Tributyrin e khothalletsa polelo ea liprotheine tse thata ka maleng, e boloka likamano tse thata pakeng tsa lisele, e thibela li-macromolecules tse kang libaktheria le chefo hore li se ke tsa kena 'meleng,' me li boloka mosebetsi oa thibelo ea 'mele oa mala.

►Tributyrin e khothalletsa tlhahiso ea mucin (Muc) le ho matlafatsa ts'ebetso ea thibelo ea lik'hemik'hale tsa mala.

Sekhahla sa ho Pholoha se Ntlafetse

Tributyrin e ka khothaletsa motsoako oa hemoglobin, ea ntlafatsa bokhoni ba ho tsamaisa oksijene, ea matlafatsa ts'ebetso ea ts'ehetso ea bophelo, hape e ka ntlafatsa ts'ebetso ea mitochondria le ho khothaletsa motsoako oa ATP, ntho ea matla e tsamaisang ts'ebetso ea bophelo.joalo ka ho ntlafatsa sekhahla sa ho phela kapa liphoofolo.

Anti-Inflammatory & Antibacterial

►Ka ho thibela mosebetsi oa NF-Kb, TNF-α le TLR, Tributyrin e ka fokotsa tšenyo ea ho ruruha.

►Tributyrin e khothalletsa polelo ea li-peptide tsa ts'ireletso tsa endogenous, tse ka hanyetsang pathogen le kokoana-hloko ka bophara.