A chọrọ ihe ndị ọzọ na ọgwụgwọ nje nje n'ihi mmachibido iwu nke iji ọgwụ ndị a eme ihe dị ka ndị na-akwalite uto na mmepụta anụmanụ.Tributyrin na-egosi na ọ na-ekere òkè n'ịkwalite ọganihu na-eto eto na ezì, n'agbanyeghị ogo dị iche iche nke ịdị irè.

Ka ọ dị ugbu a, a maara ntakịrị ihe gbasara mmetụta ọ na-eme na nhazi microbiota.N'ime ọmụmụ ihe a, anyị nyochara mgbanwe microbiota gut nke piglets na-anata, na ịhapụ ara, 0.2% tributyrin gbakwunyere na nri basal ha.

Ndị otu Tributyrin nwere ikike ịkwalite metabolism ike yana mbelata ikike nke metabolism carbohydrate.N'ikpeazụ, nsonaazụ anyị gosipụtara na tributyrin nwere ike ịkwalite mgbanwe na mpaghara eriri afọ, nke nwere ike inye aka n'ịkwalite arụmọrụ anụmanụ mgbe a napụrụ ya ara.

Mmetụta nke Tributyrin na Gut Microbiota Shifts metụtara arụmọrụ nke Weaning Piglets

Ngwa ngwaahịa

Tributyrin (nakwa aha dị ka Glyceryl tributyrate; Glycerol tributyrate; Glycery tributyrate; propane-1,2,3-triyl tributanoate) bụ ụdị obere yinye fatty acid ester.

CAS RN: 60-01-5

EINECS Nọmba: 200-451-5

Ụdị: C15H26O6

FW: 302.36

Ọdịdị: Ọ na-acha ọcha ruo odo odo mmiri mmiri mmanụ na-esi ísì ụtọ dị ntakịrị.

Solubility: soluble na ethanol, chloroform na ether, ọ na-esiri ike na mmiri (0.010%).

Ndụ nchekwa: ọnwa 24

Ngwugwu: 25KG/Bag

Nchekwa: Akara akara na ebe akọrọ na ikuku

Tributyrinbụ triglyceride nke nwere ụmụ irighiri ihe butyrate atọ etinyere na glycerol, na-abawanye mkpokọta butyrate mgbe hydrolyzation site na pancreatic lipase.

Njirimara nke Tributyrin
Ọgbọ ọhụrụ nke butyrate-glycerol ester nke butyric acid.
100% gafere afo.
Na-ebufe acid butyric n'ime obere eriri afọ, ọ dịghị mkpa ka a kpuchie ya.
Dị ka o kwesịrị ịdị na mmiri ara ehi na mmanụ aṅụ.

Ntụle n'etiti Tributyrin & Butyrate nnu

ọkara ndụ nke butyric acid bụ 6 nkeji.Butyrate siri ike iru anụ ahụ na akụkụ ndị ọzọ dị n'èzí eriri afọ a na-enye n'ụdị butyric acid ma ọ bụ butyrate. Otú ọ dị, ọkara ndụ nke tributyrin bụ 40min, na plasma ntinye uche nke butyrate nwere ike ịnọgide na-enwe n'elu 0.1mM maka 0.5-4h site ọnụ. .

Mechanism & Atụmatụ

Onye na-eweta ike

Dị ka a maara nke ọma, butyric acid bụ obere yinye fatty acid bụ isi ike nke mkpụrụ ndụ epithelial intestinal intestinal. Ihe karịrị 70% nke ume maka itolite cell epithelial intestinal bụ butyric acid na-enye.Agbanyeghị, tributyrin na-enye uru butyric acid na-ewepụta oke n'ime afọ ma e jiri ya tụnyere ngwaahịa butyrate ndị ọzọ.

Nchekwa eriri afọ

►Tribtyrin na-akwalite mmụba na ọdịiche nke mkpụrụ ndụ epithelial mucosal intestinal, na-edozi mucosa mebiri emebi, ma gbasaa ebe dị elu maka ịmịnye nri.

►Tribtyrin na-akwalite nkwupụta nke protein njikọ siri ike na eriri afọ, na-eme ka njikọ siri ike n'etiti mkpụrụ ndụ, na-egbochi macromolecules dị ka nje bacteria na nsị ịbanye n'ime ahụ, ma na-arụ ọrụ mgbochi anụ ahụ nke eriri afọ.

►Tribtyrin na-akwalite secretion nke mucin (Muc) ma na-ewusi ọrụ mgbochi kemịkalụ eriri afọ.

Ọnụnọ nlanarị emelitere

Tributyrin nwere ike ịkwalite njikọ nke hemoglobin, melite ikike nke ibu oxygen, na-ewusi usoro nkwado ndụ ndụ ike, na-eme ka ọrụ nke mitochondria dịkwuo mma ma na-akwalite njikọ nke ATP, ihe ike nke na-eme ka ọrụ ndụ dịkwuo mma.ka ọ dị mma maka ịdị ndụ ma ọ bụ anụmanụ.

Anti-inflammatory & Antibacteria

►Site na igbochi ọrụ nke NF-Kb, TNF-α na TLR, Tributyrin nwere ike ibelata mmebi ahụ ọkụ.

►Tribtyrin na-akwalite okwu nke peptides agbachitere endogenous, nke nwere ike resit pathogen na nje sara mbara.