inoa :γ- aminobutyric acid（GABA）

CAS No.:56-12-2

Nā huaʻōlelo like: 4-Aminobutyric acid;ʻAmona butyric acid;ʻakika pipecolic.

1. ʻO ka mana o GABA i ka hānai holoholona pono e mau i kekahi manawa.ʻO ka ʻai meaʻai pili pili i ka hana hana o nā holoholona a me nā moa.Ma ke ʻano he hana ʻano paʻakikī, mālama nui ʻia ka hānai ʻana e ka ʻōnaehana nerve waena.ʻO ke kikowaena satiety (Ventromedial nucleus o ka hypothalamus) a me ke kikowaena hānai (lateral hypothalamus area) he mea hoʻoponopono holoholona.

Hiki i ke kikowaena kumu o ka meaʻai GABA ke hoʻoulu i ka hānai holoholona ma ke kāohi ʻana i ka hana o ke kikowaena satiety, hoʻonui i ka hiki ke hānai holoholona.Ua hōʻike ʻia nā haʻawina he nui i ka hoʻokomo ʻana i kahi ʻano nui o ka GABA i loko o nā ʻāpana lolo like ʻole o nā holoholona hiki ke hoʻoikaika nui i ka hānai holoholona a loaʻa kahi hopena pili.ʻO ka hoʻohuiʻana i ka GABA i ka meaʻai kumu o nā puaʻa momona e hiki ke hoʻonui nui i ka hānai puaʻa, hoʻonui i ke kaumaha, aʻaʻole e ho'ēmi i ka hoʻohanaʻana i ka protein hānai.

2. ʻO ka hopena o GABA ma ka ʻai ʻana o ka ʻōpū a me ka ʻōnaehana Endocrine Ma ke ʻano he neurotransmitter a modulator paha, pāʻani nui ʻo GABA i ka peripheral Autonomic nervous system of vertebrates.

3. ʻO ka hopena o GABA i ka motility gastrointestinal.He nui loa ka GABA i loko o ka ʻōpū o ka ʻōpū, a ʻo GABA immunoreactive nerve fibers a i ʻole nā ​​​​pūnaewele aʻalolo maikaʻi i loaʻa i loko o ka ʻōnaehana nerve a me ka membrane o ka ʻōpū o ka maʻi mammalian, ʻo GABA endocrine nā mea i hoʻohele pū ʻia i ka epithelium o Gastric mucosa.He hopena hoʻoponopono ko GABA i nā ʻiʻo ʻiʻo maʻemaʻe o ka ʻōpū, nā cell endocrine a me nā cell endocrine non.Loaʻa i ka Exogenous GABA kahi hopena pale nui i nā ʻāpana ʻōpū o ka ʻiole, i hōʻike ʻia i ka hoʻomaha a me ka hoʻohaʻahaʻa amplitude contraction o nā ʻāpana ʻōpū i hoʻokaʻawale ʻia.ʻO kēia ʻano hana paʻa o GABA ma o ke kāohi ʻana i nā ʻōnaehana cholinergic a / a i ʻole cholinergic o ka ʻōpū, E hana me ka ʻole o ka ʻōnaehana adrenergic;Hiki iā ia ke hoʻopaʻa kūʻokoʻa i ka mea loaʻa GABA e pili ana i nā ʻiʻo ʻiʻo maʻemaʻe o ka ʻōpū.

4. Hoʻoponopono ka GABA i ka metabolism holoholona.Hiki i ka GABA ke loaʻa i ka nui o nā hopena i loko o ka ʻōnaehana gastrointestinal ma ke ʻano he hormone kūloko, e like me kekahi mau glands a me nā hormones endocrine.Ma lalo o nā kūlana in vitro, hiki i ka GABA ke hoʻoulu i ka mea huna o ka hormone ulu ma ka hoʻoulu ʻana i ka mea loaʻa GABA i ka ʻōpū.Hiki i ka hormone ulu holoholona ke hoʻoikaika i ka synthesis o kekahi mau peptides i loko o ke ake (e like me IGF-1), e hoʻonui i ka nui o ka metabolic o nā ʻiʻo muscle, e hoʻonui i ka ulu ulu a me ka hoʻololi ʻana i nā holoholona. nā meaʻai hānai i loko o ke kino holoholona;Hiki ke noʻonoʻoʻia e pili ana ka uluʻana o ka hopena o ka GABA i kona hoʻoponoponoʻana i ka hana hormone ulu ma o ka hoʻopiliʻana i ka hana o ka pūnaewele Endocrine nerve.