Tau ntau xyoo lawm butyric acid tau siv rau hauv kev lag luam pub khoom noj los txhim kho lub plab noj qab haus huv thiab kev ua haujlwm ntawm tsiaj.Ntau tiam neeg tshiab tau raug qhia los txhim kho kev tuav ntawm cov khoom thiab nws cov kev ua tau zoo txij li thawj qhov kev sim ua tiav hauv 80s.

Tau ntau xyoo lawm butyric acid tau siv rau hauv kev lag luam pub khoom noj los txhim kho lub plab noj qab haus huv thiab kev ua haujlwm ntawm tsiaj.Ntau tiam neeg tshiab tau raug qhia los txhim kho kev tuav ntawm cov khoom thiab nws cov kev ua tau zoo txij li thawj qhov kev sim ua tiav hauv 80s..

1. Kev loj hlob ntawm butyric acid li pub additive

1980s> Butyric Acid siv los txhim kho rumen txoj kev loj hlob

1990s> ntsev ntawm butyrin acid siv rau kev txhim kho tsiaj txhu

2000s> coated salts tsim: zoo plab hnyuv muaj thiab tsis hnov ​​tsw

Xyoo 2010s> Ib qho tshiab esterified thiab muaj txiaj ntsig zoo dua butyric acid tau qhia

Niaj hnub no lub khw yog dominated los ntawm kev tiv thaiv zoo butyric acid.Pub cov neeg tsim khoom ua haujlwm nrog cov additives no tsis muaj teeb meem nrog cov teeb meem tsis hnov ​​tsw thiab cov nyhuv ntawm cov tshuaj ntxiv rau lub plab noj qab haus huv thiab kev ua haujlwm zoo dua.Qhov teeb meem nrog cov pa coated cov khoom yog txawm li cas los qhov tsawg concentration ntawm butyric acid.Coated ntsev feem ntau muaj 25-30% butyric acid, uas yog tsawg heev.

Txoj kev loj hlob tshiab tshaj plaws hauv butyric acid raws li pub additives yog kev txhim kho ntawm ProPhorce ™ SR: glycerol esters ntawm butyric acid.Cov triglycerides ntawm butyric acid tuaj yeem pom muaj nyob hauv cov mis nyuj thiab zib ntab.Lawv yog cov muaj txiaj ntsig zoo tshaj plaws ntawm kev tiv thaiv butyric acid nrog cov ntsiab lus ntawm butyric acid txog 85%.Glycerol muaj chav kom muaj peb butyric acid molecules txuas rau nws los ntawm kev hu ua 'ester bonds'.Cov kev sib txuas muaj zog no muaj nyob rau hauv tag nrho cov triglycerides thiab lawv tsuas tuaj yeem tawg los ntawm cov enzymes tshwj xeeb (lipase).Hauv cov qoob loo thiab plab tributyrin nyob twj ywm thiab nyob rau hauv txoj hnyuv uas pancreatic lipase tau yooj yim muaj cov butyric acid tso tawm.

Cov txheej txheem ntawm esterifying butyric acid tau ua pov thawj tias yog txoj hauv kev zoo tshaj plaws ntawm kev tsim cov ntxhiab tsw butyric acid uas tso tawm qhov twg koj xav tau: hauv plab.

Tributyrin muaj nuj nqi

1.Kho cov kab mob hauv plab me me ntawm cov tsiaj thiab inhibit cov kab mob plab hnyuv.

2.Txhim kho kev nqus thiab siv cov as-ham.

3.Muaj peev xwm txo tau raws plab thiab kev ntxhov siab ntawm cov tsiaj hluas.

4.Ua kom cov ciaj sia taus thiab qhov hnyav txhua hnub ntawm cov tsiaj hluas.