ʻĀpanaUa mālama ʻia ka hoʻokolohua e aʻo i nā hopena o ka diludine i ka hoʻomoe ʻana a me ka maikaʻi o ka hua manu i nā moa a me ka hoʻokokoke ʻana i ke ʻano o nā hopena ma ka hoʻoholo ʻana i nā kuhikuhi o nā hua manu a me nā serum parameter 1024 ROM ua māhele ʻia i ʻehā mau pūʻulu i loaʻa i ʻehā mau replika o 64 Hens kēlā me kēia, Ua loaʻa i nā hui lapaʻau ka meaʻai basal like i hoʻohui ʻia me 0, 100, 150, 200 mg/kg diludine no 80 d.Penei ka hopena.ʻO ka hoʻohui ʻana i ka diludine i ka meaʻai i hoʻomaikaʻi i ka hana hoʻomoe ʻana o nā moa, ʻo ia ka 150 mg/kg lapaʻau maikaʻi loa;Ua hoʻonui ʻia ka nui o ka waiho ʻana e 11.8% (p<0.01), ua hoʻemi ʻia ka huli ʻana o ka hua manu e 10.36% (p<0 01).Ua hoʻonui ʻia ka paona hua me ka hoʻonui ʻia o ka diludine.Ua hoʻemi nui ka Diludine i ka nui o ka serum o ka uric acid (p<0.01);ʻO ka hoʻohui ʻana i ka diludine i hōʻemi nui i ka serum Ca2+a me ka maʻiʻo phosphate inorganic, a me ka hoʻonui ʻana i ka hana o ka alkine phosphatase (ALP) o ka serum (p<0.05), no laila ua loaʻa nā hopena koʻikoʻi i ka hōʻemi ʻana i ka haki ʻana o ka hua manu (p<0.05) a me ka abnormality (p <0.05);Ua hoʻonui nui ka diludine i ke kiʻekiʻe albumen.ʻO ka waiwai Haugh (p <0.01), ka mānoanoa o ka pūpū a me ke kaumaha o ka pūpū (p<0.05), 150 a me 200mg/kg diludine i hoʻemi pū i ka nui o ka cholesterol ma ka hua hua manu (p<0 05), akā ua hoʻonui ʻia ke kaumaha o ka hua manu (p <0.05).Eia kekahi, hiki i ka diludine ke hoʻonui i ka hana o ka lipase (p <0.01), a hoʻemi i ka ʻike o ka triglyceride (TG3) (p<0.01) a me ka cholesterol (CHL) (p<0 01) i loko o ka serum, ua hoʻemi ia i ka pakeneka o ka momona o ka ʻōpū. (p<0.01) a me ka momona o ka ate (p<0.01), hiki ke pale aku i ka moa mai ka momona o ka ate.Ua hoʻonui nui ka Diludine i ka hana o SOD i ka serum (p<0 01) i ka wā i hoʻohui ʻia ai i ka meaʻai no ka ʻoi aku o 30d.Akā naʻe, ʻaʻohe ʻokoʻa koʻikoʻi i ʻike ʻia i nā hana o GPT a me GOT o ka serum ma waena o ka mana a me ka hui mālama ʻia.Ua manaʻo ʻia he hiki i ka diludine ke pale i ka membrane o nā cell mai ka oxidation
ʻōlelo nuiDiludine;moa;SOD;cholesterol;triglyceride, lipase
ʻO ka diludine ka mea hou non-nutritive anti-oxidation vitamin additive a loaʻa nā hopena[1-3]no ka hoʻopaʻa ʻana i ka oxidation o ka membrane biological a me ka hoʻopaʻa ʻana i ke kino o nā cell biological, etc.[4]no ka paipai ʻana i ka ulu ʻana o ka moa a me ke kūʻē ʻana i ka hau a me ka ʻelemakule no kekahi mau mea kanu.Ua hōʻike ʻia ʻaʻole hiki i ka diludine ke hoʻoikaika i ka ulu ʻana o ka holoholona, akā e hoʻomaikaʻi i ka hana hānau ʻana o nā holoholona me ka maopopo a hoʻomaikaʻi i ka nui o ka hāpai ʻana, ka hoʻopuka ʻana o ka waiū, ka hua manu a me ka helu hatching o ka holoholona wahine.[1, 2, 5-7].Ua hoʻomaka ʻia ke aʻo ʻana o ka diludine ma Kina mai ka makahiki 1980, a ʻo ka hapa nui o nā noiʻi e pili ana i ka diludine ma Kina ua paʻa i ka hoʻohana ʻana i ka hopena a hiki i kēia manawa, a ua hōʻike ʻia nā hoʻāʻo liʻiliʻi no ka hoʻomoe ʻana i nā moa.Ua hōʻike ʻo Chen Jufang (1993) e hiki i ka diludine ke hoʻomaikaʻi i ka puka o ka hua manu a me ke kaumaha o ka hua manu, akā ʻaʻole i hohonu.[5]ke aʻo ʻana i ke ʻano hana o ia mea.No laila, ua hoʻokō mākou i ke aʻo ʻōnaehana o ka hopena a me ka hana o ia mea ma ka hānai ʻana i nā moa hoʻomoe me ka meaʻai doped me ka diludine, a ua hōʻike ʻia kekahi hapa o ka hopena i kēia manawa:
Papa 1 Ka hoʻohui ʻana a me nā mea momona o ka ʻai hoʻokolohua
%
------------------------------------------------- -------------------------------------------
Ka hoʻohui ʻana o ka meaʻai Mea ʻai meaʻai
------------------------------------------------- -------------------------------------------
Kāna 62 ME③ 11.97
ʻO ka pīni pulu 20 CP 17.8
ʻAi iʻa 3 Ca 3.42
ʻAi rapeseed 5 P 0.75
ʻAi iwi 2 M a me 0.43
ʻAi pōhaku 7.5 M a me Cys 0.75
Methionine 0.1
Paakai 0.3
Multivitamin① 10
Nā mea ʻimi ② 0.1
------------------------------------------------- ---------------------------------------
① Multivitamin: 11mg o riboflavin, 26mg o ka folic acid, 44mg o ka oryzanin, 66mg o ka niacin, 0.22mg o biotin, 66mg o B6, 17.6ug o B12, 880mg o choline, 30mg o VK, V 66IU oE, 6600ICU o VDa me 20000ICU o VA, hoʻohui ʻia i kēlā me kēia kilokani o ka meaʻai;a hoʻohui ʻia ka 10g multivitamin i kēlā me kēia 50kg o ka meaʻai.
② Nā mea hoʻoheheʻe (mg/kg): 60 mg o Mn, 60mg o Zn, 80mg o Fe, 10mg o Cu, 0.35mg o I a me 0.3mg o Se i hoʻohui ʻia i kēlā me kēia kilokani o ka meaʻai.
③ ʻO ka ʻāpana o ka ikehu metabolizable e pili ana iā MJ/kg.
1. Nā mea hana a me ke ʻano
1.1 Mea ho'āʻo
ʻO Beijing Sunpu Biochem.& ʻenehana.Pono ʻo Co., Ltd. e hāʻawi i ka diludine;a e pili ana ka holoholona hoao i na moa hoomoe kalepa Roma he 300 la.
ʻAi hoʻāʻo: pono e hoʻomākaukau ʻia ka meaʻai hoʻokolohua e like me ke kūlana maoli i ka wā o ka hana ʻana ma ke kumu o ka maʻamau NRC, e like me ka hōʻike ʻana ma ka Papa 1.
1.2 Hana ho'āʻo
1.2.1 Hoʻokolohua hānai: pono e hoʻokō ʻia ka hoʻokolohua hānai ma ka mahiʻai o Hongji Company ma Jiande City;1024 Pono e koho ʻia nā moa hoʻomoe Roma a māhele ʻia i ʻehā mau pūʻulu ma ke ʻano he 256 mau ʻāpana (pono e hana hou ʻia kēlā me kēia hui no ʻehā manawa, a ʻo kēlā me kēia moa he 64 manawa);pono e hānaiʻia nā moa me nā meaʻaiʻehā me nā mea likeʻole o ka diludine, a me 0, 100, 150, 200mg / kg o nā meaʻai e hoʻohuiʻia no kēlā me kēia hui.Ua hoʻomaka ka hoʻokolohua ma ʻApelila 10, 1997;a hiki i na moa ke loaa ka ai a lawe wale i ka wai.Pono e hoʻopaʻa ʻia ka meaʻai i lawe ʻia e kēlā me kēia pūʻulu, ka helu hoʻomoe, ka hoʻopuka ʻana o ka hua manu, ka hua haʻi a me ka helu o nā hua manu ʻino.Eia kekahi, ua pau ka hoʻāʻo ʻana ma Iune 30, 1997.
1.2.2 Ana o ka maikaʻi o ka hua: 20 mau hua e lawe ʻole ʻia i ka wā i hoʻokō ʻia ai ka hoʻāʻo ʻana i ʻehā mau lā 40 i mea e ana ai i nā hōʻailona e pili ana i ka maikaʻi o ka hua, e like me ka huaʻōlelo hua manu, ʻāpana haugh, ke kaumaha pili o ka pūpū, ka ʻO ka mānoanoa o ka pūpū, ka helu yolk, ke kaumaha pili o ka yolk, a me nā mea ʻē aʻe, pono e ana ʻia ka ʻike o ka cholesterol ma ka hoʻohana ʻana i ke ʻano COD-PAP i mua o ka Cicheng reagent i hana ʻia e Ningbo Cixi Biochemical Test Plant.
1.2.3 Ana o ka serum biochemical index: 16 mau moa hoao mai kela hui keia manawa i ka hoao ana no 30 la a i ka pau ana o ka hoao ana e hoomakaukau i ka serum ma hope o ka laʻana o ke koko mai ka vein ma ka eheu.Pono e mālama ʻia ka serum ma kahi haʻahaʻa haʻahaʻa (-20 ℃) no ke ana ʻana i nā kuhikuhi biochemical pili.Pono e ana ʻia ka pākēneka o ka momona o ka ʻōpū a me ka lipid ate ma hope o ka pepehi ʻana a me ka lawe ʻana i ka momona o ka ʻōpū a me ke ake i ka pau ʻana o ke koko.
Pono e ana ʻia ka superoxide dismutase (SOD) me ka hoʻohana ʻana i ke ʻano saturation i mua o ka pahu reagent i hana ʻia e ka Beijing Huaqing Biochem.& ʻenehana.Keʻena noiʻi.Pono e ana ʻia ka ʻakika uric (UN) i loko o ka serum me ka hoʻohana ʻana i ke ʻano U ricase-PAP i mua o ke kit reagent Cicheng;pono e ana i ka triglyceride (TG3) me ka hoʻohana ʻana i ke ʻano GPO-PAP hoʻokahi ʻanuʻu i mua o ka pahu Cicheng reagent;pono e ana i ka lipase ma ka hoohana ana i ka nephelometry ma ke alo o ka Cicheng reagent kit;Pono e ana i ka serum total cholesterol (CHL) me ka hoʻohana ʻana i ke ʻano COD-PAP i mua o ka pahu Cicheng reagent;pono e ana i ka glutamic-pyruvic transaminase (GPT) me ka hoohana ana i ka colorimetry ma ke alo o ka Cicheng reagent kit;pono e ana i ka glutamic-oxalacetic transaminase (GOT) me ka hoʻohana ʻana i ka colorimetry i mua o ka pahu Cicheng reagent;pono ke ana 'ia ka alkaline phosphatase (ALP) me ka hoohana ana i ke kaina helu ma ke alo o ka pahu reagent Cicheng;ka ion calcium (Ca2+) i loko o ka serum e pono ke ana ma ka hoʻohana ʻana i ka methylthymol blue complexone me ke ʻano o ke ʻano o ka Cicheng reagent kit;pono e ana i ka phosphorus inorganic (P) me ka hoohana ana i ke ano polu molybdate ma ke alo o ka pahu hoohuoi Cicheng.
2 Ka hopena ho'āʻo
2.1 Ka hopena i ka hana ʻana
Hōʻike ʻia nā hana hoʻomoe o nā hui like ʻole me ka hoʻohana ʻana i ka diludine ma ka Papa 2.
Papa 2 Hana ʻia nā moa i hānai ʻia me ka ʻai kumu i hoʻohui ʻia me nā pae ʻehā o ka diludine
| Ka nui o ka diludine e hoʻohui ʻia (mg/kg) | ||||
| 0 | 100 | 150 | 200 | |
| ʻai ʻai (g) |  | |||
| Ka helu kau ʻana (%) | ||||
| ʻAwelika kaumaha o ka hua (g) | ||||
| Lakiō o ka mea me ka hua | ||||
| Ka helu o ka hua manu nahaha (%) | ||||
| Ka helu o ka hua manu ʻokoʻa (%) | ||||
Mai ka Papa 2, ua hoʻomaikaʻi maikaʻi ʻia nā helu kau ʻana o nā hui āpau i hoʻohana ʻia me ka hoʻohana ʻana i ka diludine, kahi i hoʻomaikaʻi ʻia ai ka hopena i ka wā e hoʻohana ʻia ai me ka hoʻohana ʻana i ka 150mg/kg (a hiki i 83.36%), a ʻoi aku ka maikaʻi o ka 11.03% (p<0.01). me ka hui kuhikuhi;no laila ka diludine ka hopena o ka hoʻomaikaʻi ʻana i ka helu kau.ʻIke ʻia mai ka awelika kaumaha o ka hua, ke piʻi nei ke kaumaha o ka hua (p>0.05) me ka hoʻonui ʻana i ka diludine i ka ʻai i kēlā me kēia lā.Ke hoʻohālikelikeʻia me ka hui kuhikuhi,ʻaʻole maopopo kaʻokoʻa ma waena o nā'āpana hana a pau o nā hui i hoʻohanaʻia ma ka hoʻohanaʻana i ka 200mg / kg o ka diludine i ka manawa e hoʻonuiʻia ai ka 1.79g o ka meaʻai hānai;akā naʻe, ʻike mālie ʻia ka ʻokoʻa me ka piʻi ʻana o ka diludine, a ʻo ka ʻokoʻa o ka ratio o ka mea me ka hua manu ma waena o nā ʻāpana i hana ʻia e ʻike ʻia (p<0.05), a ʻoi aku ka maikaʻi o ka hopena ke 150mg/kg o ka diludine a ʻo ia. 1.25:1 i hoemiia no 10.36% (p<0.01) ke hoohalikeia me ka hui kuhikuhi.ʻIke ʻia mai ka helu haʻihaʻi o nā ʻāpana a pau i hana ʻia, hiki ke hoʻemi ʻia ka helu haʻihaʻi (p<0.05) ke hoʻohui ʻia ka diludine i ka ʻai i kēlā me kēia lā;a ua ho'emi 'ia ka pakeneka o nā hua ma'amau (p<0.05) me ka ho'onui 'ana i ka diludine.
2.2 Ka hopena i ka maikaʻi o ka hua
ʻIke ʻia ma ka Papa 3, ʻaʻole pili ka ʻano huamoa a me ka ʻumekaumaha kikoʻī o ka hua (p>0.05) ke hoʻohui ʻia ka diludine i ka ʻai i kēlā me kēia lā, a hoʻonui ʻia ke kaumaha o ka pūpū me ka hoʻonui ʻana i ka diludine i hoʻohui ʻia i kēlā me kēia lā. kahi e hoʻonui ʻia ai nā paona o nā pūpū no 10.58% a me 10.85% (p<0.05) i hoʻohālikelike ʻia me nā hui kuhikuhi ke hoʻohui ʻia ka 150 a me 200mg/kg o diludine;hoʻonui ʻia ka mānoanoa o ka pūpū hua ma ka hoʻonui ʻana i ka diludine i ka ʻai i kēlā me kēia lā, kahi e hoʻonui ʻia ai ka mānoanoa o ka pūpū hua no 13.89% (p<0.05) ke hoʻohui ʻia ka 100mg/kg o ka diludine e hoʻohālikelike ʻia me nā hui kuhikuhi, a me nā mānoanoa. hoʻonui ʻia nā pūpū hua no 19.44% (p<0.01) a me 27.7% (p<0.01) i ka wā e hoʻohui ʻia ai ka 150 a me 200mg/kg.Hoʻomaikaʻi ʻia ka ʻāpana Haugh (p<0.01) i ka wā e hoʻohui ʻia ai ka diludine, e hōʻike ana he hopena ko ka diludine e hāpai i ka hoʻohui ʻana o ka albumen mānoanoa o ka hua keʻokeʻo.ʻO ka diludine ka hana o ka hoʻomaikaʻi ʻana i ka index of yolk, akā ʻaʻole maopopo ka ʻokoʻa (p<0.05).He ʻokoʻa nā mea i loko o ka cholesterol o ka hua manu o nā hui āpau a hiki ke hoʻemi ʻia (p<0.05) ma hope o ka hoʻohui ʻana i 150 a me 200mg/kg o diludine.ʻOkoʻa nā paona pili o ka hua manu i kekahi i kekahi ma muli o ka nui o ka diludine i hoʻohui ʻia, kahi e hoʻomaikaʻi ʻia ai nā paona pili o ka yolk no 18.01% a me 14.92% (p<0.05) ke hoʻohālikelike ʻia ka 150mg/kg a me 200mg/kg. me ka hui kuhikuhi;No laila, ʻo ka diludine kūpono ka hopena o ka hoʻoikaika ʻana i ka synthesis o ka hua manu.
Papa 3 Nā hopena o ka diludine i ka maikaʻi o ka hua
| Ka nui o ka diludine e hoʻohui ʻia (mg/kg) | ||||
| ʻAno hua | 0 | 100 | 150 | 200 |
| Helu hua manu (%) |  | |||
| Kaumaha kiko hua (g/cm3) | ||||
| Kaumaha pili o ka iwi hua manu (%) | ||||
| ʻO ka mānoanoa o ka ʻili hua manu (mm) | ||||
| ʻĀpana Haugh (U) | ||||
| Hua'ōlelo huaʻala hua (%) | ||||
| Cholesterol o ka hua manu (%) | ||||
| Kaumaha pili o ka hua manu (%) | ||||
2.3 Nā hopena i ka pākēneka momona o ka ʻōpū a me ka momona o ke ake o nā moa hoomoe.
E nānā i ka Kiʻi 1 a me ka Kiʻi 2 no nā hopena o ka diludine i ka pākēneka momona o ka ʻōpū a me ka maʻi o ka momona o ke ake o nā moa hoʻomoe.
Helu 1 Ka hopena o ka diludine ma ka pakeneka o ka momona o ka opu (PAF) o na moa hoomoe.
| Pākēneka o ka momona o ka ʻōpū | |
| Ka nui o ka diludine e hoʻohui ʻia |
Kiʻi 2 Ka hopena o ka diludine i ka momona o ke akepaʻa (LF) o nā moa hoʻomoe
| ʻO ka momona o ka ate | |
| Ka nui o ka diludine e hoʻohui ʻia |
ʻIke ʻia mai ka Figure 1, ua hoʻemi ʻia nā pākēneka o ka momona o ka ʻōpū o ka hui hoʻāʻo no 8.3% a me 12.11% (p<0.05) i kēlā me kēia ke hoʻohālikelike ʻia ka 100 a me 150mg/kg o ka diludine me ka hui kuhikuhi, a hoʻemi ʻia ka pākēneka o ka momona o ka ʻōpū. no 33.49% (p<0.01) ke hoʻohui ʻia ka 200mg/kg o diludine.ʻIke ʻia mai ka Figure 2, ua hoʻemi ʻia nā mea momona o ke akepaʻa (maloʻo loa) i hana ʻia e 100, 150, 200mg/kg o diludine no 15.00% (p<0.05), 15.62% (p<0.05) a me 27.7% (p<0.05) 0.01) i hoʻohālikelike ʻia me ka hui kuhikuhi;No laila, ʻo ka diludine ka hopena o ka hoʻohaʻahaʻa ʻana i ka pākēneka o ka momona o ka ʻōpū a me ka momona o ke akepaʻa o ka waiho ʻana i ʻike maopopo ʻia, kahi maikaʻi loa ka hopena ke hoʻohui ʻia ka 200mg / kg o diludine.
2.4 Ka hopena i ka helu helu biochemical serum
ʻIke ʻia mai ka Papa 4, ʻaʻole maopopo ka ʻokoʻa ma waena o nā ʻāpana i hana ʻia i ka Phase I (30d) o ka hoʻāʻo SOD, a ʻoi aku ka kiʻekiʻe o nā helu helu biochemical serum o nā hui āpau kahi i hoʻohui ʻia ai ka diludine i ka Phase II (80d) o ka hoʻāʻo. ma mua o ka hui kuhikuhi (p<0.05).Hiki ke hoʻemi ʻia ka uric acid (p<0.05) i ka serum ke hoʻohui ʻia ka 150mg/kg a me 200mg/kg o diludine;ʻoiai ka hopena (p<0.05) i loaʻa i ka wā e hoʻohui ʻia ai ka 100mg / kg o diludine i ka Phase I. Hiki i ka diludine ke hoʻemi i ka triglyceride i loko o ka serum, kahi maikaʻi loa ka hopena (p<0.01) i ka hui i ka wā 150mg/kg o Hoʻohui ʻia ka diludine i ka Phase I, a ʻoi aku ka maikaʻi i ka hui ke hoʻohui ʻia ka 200mg/kg o diludine i ka Phase II.Hoʻemi ʻia ka nui o ka cholesterol i loko o ka serum me ka hoʻonui ʻana i ka diludine i hoʻohui ʻia i ka meaʻai i kēlā me kēia lā, ʻoi aku ka nui o ka nui o ka cholesterol i loko o ka serum e hoʻemi ʻia no 36.36% (p<0.01) a me 40.74% (p<0.01) i ka wā 150mg/kg. a me 200mg/kg o diludine i hoʻohui ʻia i ka Phase I i hoʻohālikelike ʻia me ka hui kuhikuhi, a hoʻemi ʻia no 26.60% (p<0.01), 37.40% (p<0.01) a me 46.66% (p<0.01) i ka wā 100mg/kg, 150mg. / kg a me 200mg/kg o diludine i hoʻohui ʻia i ka Phase II i hoʻohālikelike ʻia me ka hui kuhikuhi.Eia kekahi, hoʻonui ʻia ka ALP me ka hoʻonui ʻana i ka diludine i hoʻohui ʻia i ka meaʻai i kēlā me kēia lā, ʻoiai ʻoi aku ka kiʻekiʻe o nā waiwai o ALP i loko o ka hui i hoʻohui ʻia ʻo 150mg/kg a me 200mg/kg o ka diludine ma mua o ka hui kuhikuhi (p<0.05).
Papa 4 Nā hopena o ka diludine ma nā ʻāpana serum
| Ka nui o ka diludine e hoʻohui ʻia (mg/kg) ma ka Māhele I (30d) o ka hoʻāʻo | ||||
| 'ikamu | 0 | 100 | 150 | 200 |
| Superoxide dismutase (mg/mL) |  | |||
| ʻakika uric | ||||
| Triglyceride (mmol/L) | ||||
| Lipase (U/L) | ||||
| Kolekele (mg/dL) | ||||
| Glutamic-pyruvic transaminase (U/L) | ||||
| Glutamic-oxalacetic transaminase (U/L) | ||||
| Alkaline phosphatase (mmol/L) | ||||
| ʻO ka iona calcium (mmol/L) | ||||
| phosphorus anoano (mg/dL) | ||||
| Ka nui o ka diludine e hoʻohui ʻia (mg/kg) i ka Phase II (80d) o ka hoʻāʻo | ||||
| 'ikamu | 0 | 100 | 150 | 200 |
| Superoxide dismutase (mg/mL) |  | |||
| ʻakika uric | ||||
| Triglyceride (mmol/L) | ||||
| Lipase (U/L) | ||||
| Kolekele (mg/dL) | ||||
| Glutamic-pyruvic transaminase (U/L) | ||||
| Glutamic-oxalacetic transaminase (U/L) | ||||
| Alkaline phosphatase (mmol/L) | ||||
| ʻO ka iona calcium (mmol/L) | ||||
| phosphorus anoano (mg/dL) | ||||
3 Ka nānā 'ana a me ke kūkākūkā
3.1 Ua hoʻomaikaʻi ka diludine i ka hoʻāʻo ʻana i ka nui o ka waiho ʻana, ke kaumaha o ka hua manu, ka ʻāpana Haugh a me ke kaumaha pili o ka yolk hua, i hōʻike ʻia he hopena ka diludine i ka hoʻoulu ʻana i ka assimilation o ka protein a me ka hoʻomaikaʻi ʻana i ka nui o ka synthesis o ka mānoanoa. albumen o ka hua keokeo a me ka protein o ka hua manu.Eia hou, ua hoʻemi ʻia ka ʻike o ka uric acid i loko o ka serum;a ua ʻae ʻia ʻo ka hoʻemi ʻana o ka ʻike o ka nitrogen non-protein i loko o ka serum ua hoʻemi ʻia ka wikiwiki catabolism o ka protein, a ua hoʻopaneʻe ʻia ka manawa paʻa o ka nitrogen.Hāʻawi kēia hopena i ke kumu o ka hoʻonui ʻana i ka paʻa ʻana o ka protein, ka hāpai ʻana i ka hoʻomoe ʻana i nā hua a me ka hoʻomaikaʻi ʻana i ke kaumaha o ka hua o nā moa hoʻomoe.Ua hōʻike ʻia ka hopena o ka hoʻāʻo e ʻoi aku ka maikaʻi o ka waiho ʻana i ka wā i hoʻohui ʻia ai ka 150mg/kg o diludine, ʻo ia ka mea i kūlike me ka hopena.[6,7]ʻO Bao Erqing a me Qin Shangzhi a loaʻa ma ka hoʻohui ʻana i ka diludine i ka wā hope o ka hoʻomoe ʻana i nā moa.Ua hoʻemi ʻia ka hopena inā ʻoi aku ka nui o ka diludine ma mua o 150mg/kg, ʻo ia paha no ka hoʻololi ʻana o ka protein.[8]Ua hoʻopilikia ʻia ma muli o ka nui o ka dosage a me ka haʻahaʻa nui o ka metabolism o ke kino i ka diludine.
3.2 ʻO ke kuʻina o Ca2+i ka serum o ka waiho huamoa ua hoemiia, ka P i ka serum ua hoemiia i ka hoomaka ana a me ka ALP hana i hoonui maopopo i mua o ka diludine, i hoike ia diludine pili i ka metabolism o Ca a me P maopopo.Ua hōʻike ʻo Yue Wenbin e hiki i ka diludine ke hāpai i ka absorption[9] nā mea mineral Fe a me Zn;Aia ka ALP i loko o nā ʻiʻo, e like me ke ake, ka iwi, ka ʻōpū ʻōpū, ka puʻupaʻa, a pēlā aku;ʻO ka ALP i loko o ka serum mai ke ake a me ka iwi ka nui;ALP i loko o ka iwi i loko o ka osteoblast ka nui a hiki ke hoʻohui i ka phosphate ion me ka Ca2 mai ka serum ma hope o ka hoʻololi ʻana ma o ka paipai ʻana i ka decomposition o ka phosphate a me ka hoʻonui ʻana i ka ʻike o ka phosphate ion, a waiho ʻia ma ka iwi ma ke ʻano o ka hydroxyapatite, etc. .Eia kekahi, ua hōʻemi ʻia ka hapa o ka hua manu i haʻihaʻi ʻia a me ka pākēneka o ka hua manu ma ke ʻano o ka hoʻomoe ʻana, ʻo ia hoʻi ka wehewehe ʻana i kēia wahi.
3.3 Ua hoʻemi ʻia ka momona o ka ʻōpū a me ka momona o ke akepaʻa o nā moa hoʻomoe ma ka hoʻohui ʻana i ka diludine i ka meaʻai, ʻo ia ka mea i hōʻike ʻia i ka diludine ka hopena o ke kāohi ʻana i ka synthesis o ka momona i ke kino.Eia hou, hiki i ka diludine ke hoʻomaikaʻi i ka hana o ka lipase i ka serum i ka wā mua;Ua hoʻonui ʻia ka hana o ka lipase i loko o ka hui kahi i hoʻohui ʻia ai ka 100mg/kg o ka diludine, a ua hoʻemi ʻia nā mea o ka triglyceride a me ka cholesterol i loko o ka serum (p<0.01), kahi i hōʻike ʻia e hiki i ka diludine ke hoʻoikaika i ka decomposition o triglyceride. a hoʻopaʻa i ka synthesis o ka cholesterol.Hiki ke kāohi ʻia ka waiho ʻana o ka momona ma muli o ka enzyme o ka lipid metabolism i loko o ke ake[10,11], a me ka hoemi ana o ka cholesterol ma ka hua huamoa ua wehewehe pu i keia wahi [13].Ua hōʻike ʻo Chen Jufang e hiki i ka diludine ke kāohi i ka hana ʻana o ka momona i loko o ka holoholona a hoʻomaikaʻi i ka pākēneka ʻiʻo wīwī o nā broilers a me ka puaʻa, a loaʻa iā ia ka hopena o ka mālama ʻana i ka momona momona.Ua akaka ka hopena o ka ho'āʻo ʻana i kēia ʻano hana, a ʻo ka ʻoki ʻana a me ka nānā ʻana o nā moa hoʻāʻo i hōʻike pū ʻia e hiki i ka diludine ke hoʻemi i ka nui o ka ulu ʻana o ka momona o nā moa hoʻomoe.
3.4 ʻO GPT a me GOT nā hōʻailona koʻikoʻi ʻelua e hōʻike ana i nā hana o ke ake a me ka puʻuwai, a hiki ke pohō ke ake a me ka puʻuwai inā kiʻekiʻe nā hana o ia mea.ʻAʻole i hoʻololi ʻia nā hana o GPT a me GOT i ka serum i ka wā i hoʻohui ʻia ai ka diludine i ka hoʻāʻo, i hōʻike ʻia ʻaʻole i hōʻeha ʻia ke ake a me ka puʻuwai;Eia hou, ua hōʻike ʻia ka hopena ana o SOD e hiki ke hoʻomaikaʻi ʻia ka hana o SOD i loko o ka serum i ka wā i hoʻohana ʻia ai ka diludine no kekahi manawa.SOD e pili ana i ka scavenger nui o ka superoxide free radical i loko o ke kino;He mea koʻikoʻi ia no ka mālama pono ʻana o ka membrane biological, hoʻomaikaʻi i ka hiki ke pale i ke kino a mālama i ke olakino o ka holoholona ke hoʻonui ʻia ka ʻike o ka SOD i ke kino.Ua hōʻike ʻo Quh Hai, a pēlā aku, hiki i ka diludine ke hoʻomaikaʻi i ka hana o 6-glucose phosphate dehydrogenase i loko o ka membrane biological a hoʻopaʻa i nā ʻiʻo [2] o ka cell biological.Ua kuhikuhi ʻo Sniedze i ka diludine i kāohi i ka hana [4] o NADPH cytochrome C reductase maopopo ma hope o ke aʻo ʻana i ka pilina ma waena o ka diludine a me ka enzyme pili i ka NADPH kikoʻī electron hoʻololi kaulahao i ka microsome ate ʻiole.Ua kuhikuhi pū ʻo Odydents ua pili ka diludine [4] i ka ʻōnaehana oxidase composite a me ka enzyme microsomal e pili ana me NADPH;a ʻo ke ʻano o ka hana o ka diludine ma hope o ke komo ʻana i loko o ka holoholona e pāʻani i ke ʻano o ka pale ʻana i ka oxidation a me ka pale ʻana i ka membrane biological [8] ma ke kāohi ʻana i ka hana o ka electron transfer NADPH enzyme o ka microsome a me ke kāohi ʻana i ke kaʻina peroxidation o ka pūhui lipid.Ua hōʻike ka hopena hōʻike i ka hana pale o ka diludine i ka membrane biological mai nā loli o ka hana SOD i nā loli o nā hana o GPT a me GOT a hōʻoia i nā hopena noiʻi o Sniedze a me Odydents.
Kuhikuhi
1 Zhou Kai, Zhou Mingjie, Qin Zhongzhi, etc. E aʻo i ka diludine o ka hoʻomaikaʻi ʻana i ka hana hānau o nā hipaJ. Mauu aLivestock 1994 (2): 16-17
2 Qu Hai, Lv Ye, Wang Baosheng, ʻO ka hopena o ka diludine i hoʻohui ʻia i ka ʻai i kēlā me kēia lā i ka helu o ka hāpai ʻana a me ka maikaʻi o ka pua o ka ʻiʻo rabbit.J. Ka Nupepa Pake o ka Mahi Lapana1994(6): 6-7
3 Chen Jufang, Yin Yuejin, Liu Wanhan, a pela aku.Noi Hanai1993 (3): 2-4
4 Zheng Xiaozhong, Li Kelu, Yue Wenbin, etc. Kūkākūkā i ka hopena o ka noi a me ka hana o ka diludine ma ke ʻano he mea hoʻoulu ulu moa.Noi Hanai1995 (7): 12-13
5 Chen Jufang, Yin Yuejin, Liu Wanhan, a me nā mea ʻē aʻe.Noi Hanai1993 (3): 2-5
6 Bao Erqing, Gao Baohua, Ho'āʻo i ka diludine no ka hānai ʻana i ka ʻiole PekingNoi Hanai1992 (7): 7-8
7 Qin Shangzhi Ho'āʻo no ka hoʻomaikaʻi ʻana i ka huahana o nā moa ʻiʻo i ka wā hope o ka waiho ʻana me ka hoʻohana ʻana i ka diludineGuangxi Journal of Animal Husbandry & Veterinary Medicine1993.9(2): 26-27
8 Dibner J Jl Lvey FJ Hepatic protein a me ka amino acid metabolian ma ka moa Sci moa1990.69(7): 1188- 1194
9 Yue Wenbin, Zhang Jianhong, Zhao Peie, a me nā mea ʻē aʻe. E aʻo i ka hoʻohui ʻana i ka diludine a me ka hoʻomākaukau ʻana o Fe-Zn i ka ʻai ʻana i kēlā me kēia lā o nā moa hoʻomoe.Hanai a me na holoholona1997, 18(7): 29-30
10 Mildner A na M, Steven D Clarke Porcine fatty acid synthase cloning o kahi DNA hoʻohui, ka puʻunaue kiko o konamRNA a me ka hoʻopau ʻana i ka ʻōlelo e ka somatotropin a me ka protein meaʻai J Nutri 1991, 121 900
11 W alzon RL Smon C, M orishita T, et a I Fatty liver hemorrhagic syndrome i nā moa i hānai nui ʻia i kahi meaʻai hoʻomaʻemaʻe ʻia nā hana enzyme i koho ʻia a me ka mōʻaukala ate e pili ana i ka hanohano o ke ake a me ka hana hānau.Sci moa,1993 72(8): 1479- 1491
12 Donaldson WE Lipid metabolism ma ke akepaʻa o ka moa pane i ka hānaiSci moa.1990, 69(7) : 1183- 1187
13 Ksiazk ieu icz J. K ontecka H, H ogcw sk i L He memo no ka cholesterol koko ma ke ano he hoailona o ka momona o ke kino o na pakeke.Nūpepa o Aninal a me ka ʻepekema hānai,1992, 1(3/4): 289- 294
Ka manawa hoʻouna: Jun-07-2021