AbstractChiyedzo ichi chakaitwa kuti chiongorore mhedzisiro yediludine pakukandira uye kunaka kwezai muhuku uye nzira yemaitiro emhedzisiro nekuona indexes dzezai uye serum parameters huku imwe neimwe, Mapoka ekurapa akagamuchira imwechete basal kudya yakawedzerwa ne0, 100, 150, 200 mg/kg diludine zvakateerana kwe80 d.Migumisiro yacho yakanga iri inotevera.Kuwedzerwa kwe diludine kune kudya kwakavandudza hens kuisa kushanda, iyo 150 mg / kg kurapwa kwakanakisisa;chiyero chayo chekuisa chakawedzerwa ne 11.8% (p <0.01), kutendeuka kwemazai kwakaderedzwa ne 10.36% (p <0 01).Uremu hwezai hwakawedzerwa nekuwedzera kwe diludine yakawedzerwa.Diludine yakaderera zvakanyanya serum concentration yeuric acid (p <0.01);kuwedzera diludine kwakadzikira zvakanyanya serum Ca2+uye inorganic phosphate content, uye yakawedzera basa re alkine phosphatase (ALP) ye serum (p <0.05), saka yakave nemigumisiro inokosha pakuderedza kuparara kwezai (p <0.05) uye kusagadzikana (p <0.05);diludine yakanyanya kuwedzera iyo albumen kureba.Haugh value (p <0.01), goko gobvu uye huremu hwegoko (p< 0.05), 150 uye 200mg/kg diludine zvakare yakaderedza huwandu hwecholeasterol muzai yolk (p<0 05), asi yakawedzera zai yolk huremu (p <0.05).Mukuwedzera, diludine inogona kuwedzera basa re lipase (p <0.01), uye kuderedza zvinyorwa zve triglyceride (TG3) (p <0.01) uye cholesterol (CHL) (p <0 01) mu serum, yakaderedza chikamu chemafuta emudumbu. (p<0.01) uye mafuta echiropa (p<0.01), aive nekwanisi yekudzivirira huku kubva pachiropa chine mafuta.Diludine yakawedzera zvakanyanya basa reSOD mu serum (p <0 01) payakawedzerwa kune kudya kweanopfuura 30d.Nekudaro, hapana mutsauko wakakosha wakawanikwa muzviitiko zveGPT uye GOT yeserum pakati peboka rekutonga uye rakarapwa.Izvo zvakafungidzirwa kuti diludine inogona kudzivirira membrane yemasero kubva kune oxidation
Mazwi akakoshaDiludine;hen;SOD;cholesterol;triglycerides, lipase
Iyo diludine ndiyo inova isina-nutritive anti-oxidation vhitamini yekuwedzera uye ine mhedzisiro.[1-3]yekudzivirira oxidation yebiological membrane uye kudzikamisa tishu dzemasero ehupenyu, zvichingodaro. Muma1970, nyanzvi yezvekurima yekuLatvia yaimbova Soviet Union yakaona kuti diludine ine mhedzisiro yacho.[4]yekusimudzira kukura kwehuku uye kudzivirira kutonhora nekuchembera kwezvimwe zvirimwa.Zvakataurwa kuti diludine haingogone kukurudzira kukura kwemhuka, asi kuvandudza kubereka kwemhuka zviri pachena uye kuvandudza chiyero chemimba, kubuda kwemukaka, kubuda kwezai uye kuchechenya kwechikadzi mhuka.[1, 2, 5-7].Chidzidzo che diludine muChina chakatangwa kubva kuma1980, uye ruzhinji rwezvidzidzo nezve diludine muChina zvinongoshandiswa pakushandisa kusvika pari zvino, uye miyedzo mishoma yekukandira shiri yakataurwa.Chen Jufang (1993) vakashuma kuti diludine inogona kuvandudza kubuda kwezai uye huremu hwezai rehuku, asi haina kudzika.[5]chidzidzo chemaitiro ekuita kwayo.Nokudaro, takashandisa kuongorora kwakarongeka kwemaitiro uye maitiro ayo nekudyisa shiri dzinokandira nekudya kwakakonzerwa ne diludine, uye chimwe chikamu chemugumisiro ikozvino chinoshumwa sezvinotevera:
Tafura 1 Kuumbwa uye zvinovaka muviri zvikamu zvekuedza kudya
%
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Kuumbwa kwekudya Nutrient components
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Chibage 62 ME③ 11.97
Bhinzi pulp 20 CP 17.8
Kudya hove 3 Ca 3.42
Chibharo chekudya 5 P 0.75
Bone kudya 2 M et 0.43
Kudya kwematombo 7.5 M et Cys 0.75
Methionine 0.1
Munyu 0.3
Multivitamin① 10
Kuteedzera zvinhu② 0.1
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① Multivitamin: 11mg ye riboflavin, 26mg ye folic acid, 44mg ye oryzanin, 66mg ye niacin, 0.22mg ye biotin, 66mg ye B6, 17.6ug ye B12, 880mg ye choline, 30mg ye VK, 66IUE, 6600ICU yeVDuye 20000ICU yeVA, inowedzerwa kune kirogiramu imwe neimwe yezvokudya;uye 10g multivitamin inowedzerwa kune imwe neimwe 50kg yezvokudya.
② Trace elements (mg/kg): 60 mg yeMn, 60mg yeZn, 80mg yeFe, 10mg yeCu, 0.35mg yeI uye 0.3mg yeSe inowedzerwa kune imwe kirogiramu yezvokudya.
③ Iyo unit yesimba rinoshandiswa rinoshandiswa rinoreva MJ/kg.
1. Zvishandiso uye nzira
1.1 Test zvinhu
Beijing Sunpu Biochem.& Tech.Co., Ltd. inofanira kupa iyo diludine;uye mhuka yakaedzwa ichareva huku dzeRoma dzekutengesa dzinenge dzave nemazuva mazana matatu.
Kuedza kudya: iyo bvunzo yekuyedza yekudya inofanirwa kugadzirirwa zvinoenderana nemamiriro chaiwo panguva yekugadzirwa pahwaro hweNRC chiyero, sezvakaratidzwa muTafura 1.
1.2 Nzira yekuedza
1.2.1 Kudyisa kuedza: kuedza kwekudya kunofanira kuitwa mupurazi reHongji Company muJiande City;1024 huku dzeRoma dzinokandira dzinofanira kusarudzwa dzopatsanurwa kuita mapoka mana zvisina tsarukano uye rimwe nerimwe pazvikamu mazana maviri nemakumi mashanu nenhanhatu (boka rimwe nerimwe rinofanira kudzokororwa kanokwana kana, uye huku imwe neimwe inofanira kudzokororwa ka64);huku dzinofanira kudyiswa nezvokudya zvina zvine zvakasiyana-siyana zvediludine, uye 0, 100, 150, 200mg/kg yezvokudya zvinofanira kuwedzerwa kuboka rega rega.Muedzo wakatangwa pana April 10, 1997;uye huku dzaigona kuwana zvokudya nokunwa mvura pachena.Chikafu chinotorwa neboka rega rega, chiyero chekukandira, kubuda kwezai, zai rakatyoka uye nhamba yezai risina kujairika zvinofanira kunyorwa.Uyezve, bvunzo yacho yakapera pana June 30, 1997.
1.2.2 Kuyera kwemhando yezai: Mazai makumi maviri anofanirwa kutorwa zvisina tsarukano pakaitwa bvunzo mazuva mana makumi mana kuitira kuyera zviratidzo zvine chekuita nemhando yezai, senge egg shape index, haugh unit, huremu hwegoko, goko gobvu, iyo yolk index, huremu hwehuremu hwejoka, nezvimwewo, zvakare, zviri mucholesterol muyori zvinofanirwa kuyerwa nekushandisa nzira yeCOD-PAP pamberi peCicheng reagent inogadzirwa neNingbo Cixi Biochemical Test Plant.
1.2.3 Kuyerwa kweserum biochemical index: 16 test hen dzinofanira kutorwa kubva muboka rega rega apo bvunzo yakaitwa kwemazuva makumi matatu uye kana test yapera kugadzirira serum mushure mekuenzanisa ropa kubva mutsinga iri pabapiro.Iyo serum inofanirwa kuchengetwa pane yakaderera tembiricha (-20 ℃) kuitira kuyera yakakodzera biochemical indexes.Huwandu hwemafuta emudumbu uye huwandu hwemafuta echiropa hunofanirwa kuyerwa mushure mekuuraya uye kubvisa mafuta emudumbu nechiropa pakupedza kutorwa kweropa.
Iyo superoxide dismutase (SOD) inofanirwa kuyerwa nekushandisa saturation nzira pamberi peiyo reagent kit inogadzirwa neBeijing Huaqing Biochem.& Tech.Research Institute.Uric acid (UN) muserum inofanira kuyerwa nekushandisa nzira yeU ricase-PAP pamberi peCicheng reagent kit;iyo triglyceride (TG3) inofanira kuyerwa nekushandisa GPO-PAP imwe-nhanho nzira pamberi peCicheng reagent kit;iyo lipase inofanira kuyerwa nekushandisa nephelometry pamberi peCicheng reagent kit;iyo serum yakazara cholesterol (CHL) inofanira kuyerwa nekushandisa COD-PAP nzira pamberi peCicheng reagent kit;iyo glutamic-pyruvic transaminase (GPT) inofanira kuyerwa nekushandisa colorimetry pamberi peCicheng reagent kit;iyo glutamic-oxalacetic transaminase (GOT) inofanira kuyerwa nekushandisa colorimetry pamberi peCicheng reagent kit;iyo alkaline phosphatase (ALP) inofanira kuyerwa nekushandisa chiyero nzira pamberi peCicheng reagent kit;iyo calcium ion (Ca2+) mu serum inofanira kuyerwa nekushandisa methylthymol blue complexone nzira pamberi peCicheng reagent kit;iyo inorganic phosphorus (P) inofanirwa kuyerwa nekushandisa molybdate bhuruu nzira pamberi peCicheng reagent kit.
2 Test mhinduro
2.1 Mhedzisiro yekuisa mashandiro
Kuisa mitambo yemapoka akasiyana anogadziriswa nekushandisa diludine anoratidzwa muTafura 2.
Tafura 2 Kuita kwehuku dzakadyiswa nebasal diet yakawedzerwa nezvikamu zvina zve diludine
| Nhamba ye diludine inofanira kuwedzerwa (mg/kg) | ||||
| 0 | 100 | 150 | 200 | |
| Kudya kwekudya (g) |  | |||
| Kuisa mwero (%) | ||||
| Avhareji yehuremu hwezai (g) | ||||
| Ratio yezvinhu kune zai | ||||
| Zai rakatyoka (%) | ||||
| Mwero wezai risina kujairika (%) | ||||
Kubva paTable 2, mazinga ekuisa mapoka emapoka ose anogadziriswa nekushandisa diludine anovandudzwa zviri pachena, umo mugumisiro kana uchishandiswa nekushandisa 150mg / kg yakakwana (kusvika ku83.36%), uye 11.03% (p <0.01) inovandudzwa kana ichienzaniswa neboka rereferensi;saka iyo diludine ine mhedzisiro yekuvandudza chiyero chekuisa.Kuonekwa kubva paavhareji uremu hwezai, huremu hwezai huri kuwedzera (p> 0.05) pamwe chete nekuwedzera diludine mukudya kwezuva nezuva.Kuenzaniswa neboka rekutsvaga, mutsauko pakati pezvikamu zvose zvakagadziriswa zvemapoka akashandiswa nekushandisa 200mg / kg ye diludine haisi pachena apo 1.79g yekudya kwekudya inowedzerwa;zvisinei, mutsauko unowedzera kujeka zvishoma nezvishoma pamwe chete nekuwedzera kwe diludine, uye mutsauko wehuwandu hwezvinhu kune zai pakati pezvikamu zvakagadziriswa zviri pachena (p <0.05), uye mhedzisiro yacho yakanaka kana 150mg / kg ye diludine uye iri. 1.25: 1 iyo yakaderedzwa nokuda kwe10.36% (p <0.01) kana ichienzaniswa neboka rekutsvaga.Kuonekwa kubva kune yakaputsika yezai yezvikamu zvose zvakagadziriswa, iyo yakaputsika yai (p <0.05) inogona kuderedzwa apo diludine inowedzerwa kuzvokudya zvezuva nezuva;uye chikamu chemazai asina kujairika chakaderedzwa (p <0.05) pamwe chete nekuwedzera diludine.
2.2 Mhedzisiro kumhando yezai
Kuonekwa kubva paTable 3, iyo yai chimiro indekisi uye zai chaiyo giravhiti haina kukanganiswa (p> 0.05) apo diludine inowedzerwa mukudya kwezuva nezuva, uye uremu hwegoko hunowedzera pamwe nekuwedzera diludine yakawedzerwa pakudya kwezuva nezuva, umo uremu hwematehwe hunowedzerwa 10.58% uye 10.85% (p <0.05) zvakateerana zvichienzaniswa nemapoka ereferenzi apo 150 uye 200mg/kg ye diludine inowedzerwa;kukora kwegoko rezai kunowedzerwa pamwe nekuwedzera diludine mukudya kwezuva nezuva, umo ukobvu hwegoko rezai hunowedzera 13.89% (p<0.05) apo 100mg/kg ye diludine inowedzerwa kana ichienzaniswa nemapoka ereferenzi, uye ukobvu. emateko emazai anowedzerwa 19.44% (p <0.01) uye 27.7% (p <0.01) zvichiteerana kana 150 uye 200mg/kg zvawedzerwa.Iyo Haugh unit (p <0.01) inovandudzwa zviri pachena kana diludine yawedzerwa, izvo zvinoratidza kuti diludine ine mhedzisiro yekusimudzira synthesis yealbumen yakakora yezai jena.Iyo diludine ine basa rekuvandudza index ye yolk, asi mutsauko hausi pachena (p <0.05).Zviri mukati cholesterol yezai yolk yemapoka ese akasiyana uye anogona kuderedzwa zviri pachena (p <0.05) mushure mekuwedzera 150 uye 200mg/kg ye diludine.Huremu hwehuremu hwezai rezai hwakasiyana kubva kune umwe neumwe nekuda kwehuwandu hwakasiyana hwediludine yakawedzerwa, umo huremu hwezai rezai hunovandudzwa kwe18.01% uye 14.92% (p <0.05) apo 150mg/kg uye 200mg/kg zvichienzaniswa. neboka rereferensi;saka, diludine yakakodzera ine mhedzisiro yekusimudzira synthesis yezai yolk.
Tafura 3 Migumisiro ye diludine pahutano hwezai
| Nhamba ye diludine inofanira kuwedzerwa (mg/kg) | ||||
| Egg quality | 0 | 100 | 150 | 200 |
| Chimiro chezai index (%) |  | |||
| Zai chairo regiravhiti (g/cm3) | ||||
| Huremu huremu hwegoko rezai (%) | ||||
| Kukora kwegoko rezai (mm) | ||||
| Haugh unit (U) | ||||
| Egg yolk index (%) | ||||
| Cholesterol yezai yolk (%) | ||||
| Huremu huremu hwezai yolk (%) | ||||
2.3 Mhedzisiro kuhuwandu hwemafuta emudumbu uye zviri mukati memafuta echiropa ehuku dzinokandira
Ona Mufananidzo 1 neMufananidzo 2 wezvinokonzeresa diludine kusvika pachikamu chemafuta emudumbu uye zviri mumafuta echiropa ehuku dzinokandira.
Mufananidzo 1 Mhedzisiro yediludine pachikamu chemafuta emubodominal (PAF) ehuku dzinokandira
| Percentage yeabodominal mafuta | |
| Nhamba ye diludine inofanira kuwedzerwa |
Mufananidzo 2 Mhedzisiro yediludine pamafuta echiropa (LF) ehuku dzinokandira
| Mafuta echiropa | |
| Nhamba ye diludine inofanira kuwedzerwa |
Kuonekwa kubva kuMufananidzo 1, zvikamu zvemafuta emudumbu eboka rekuedza zvakaderedzwa kusvika 8.3% uye 12.11% (p <0.05) zvakateerana apo 100 uye 150mg / kg ye diludine ichienzaniswa neboka rekutsvaga, uye chikamu chemafuta emudumbu chinoderedzwa. ye 33.49% (p <0.01) apo 200mg / kg ye diludine inowedzerwa.Kuonekwa kubva kuMufananidzo 2, mafuta echiropa (akanyatsooma) akagadziriswa ne 100, 150, 200mg/kg ye diludine maererano anoderedzwa nokuda kwe15.00% (p <0.05), 15.62% (p <0.05) uye 27.7% (p< 0.01) zvakateerana zvichienzaniswa neboka rezita;saka, iyo diludine ine mhedzisiro yekudzikisa muzana yeabodominal mafuta uye chiropa chemafuta emukati mekuisa zviri pachena, umo mhedzisiro yacho yakanaka kana 200mg/kg ye diludine yakawedzerwa.
2.4 Mhedzisiro kune serum biochemical index
Kuonekwa kubva paTafura 4, musiyano pakati pezvikamu zvakagadziriswa panguva yeChikamu I (30d) yeSOD bvunzo haisi pachena, uye serum biochemical indexes yemapoka ese ayo diludine inowedzerwa muChikamu II (80d) yebvunzo yakakwira. kupfuura boka rezita (p <0.05).Uric acid (p <0.05) muserum inogona kuderedzwa kana 150mg/kg uye 200mg/kg ye diludine yakawedzerwa;nepo mhedzisiro (p <0.05) inowanikwa apo 100mg / kg ye diludine inowedzerwa muChikamu I. Iyo diludine inogona kuderedza triglyceride mu serum, umo mugumisiro wacho unobatsira (p <0.01) muboka apo 150mg / kg ye diludine inowedzerwa muChikamu I, uye yakakwana muboka apo 200mg/kg ye diludine inowedzerwa muChikamu II.Cholesterol yose iri muserum inoderedzwa pamwe chete nekuwedzera diludine yakawedzerwa kuzvokudya zvezuva nezuva, kunyanya zviri mukati mecholesterol yose mu serum inoderedzwa nokuda kwe36.36% (p <0.01) uye 40.74% (p <0.01) zvichienderana apo 150mg / kg uye 200mg/kg ye diludine inowedzerwa muChikamu I ichienzaniswa neboka rezita, uye yakaderedzwa nokuda kwe26.60% (p <0.01), 37.40% (p <0.01) uye 46.66% (p <0.01) maererano apo 100mg / kg, 150mg / kg uye 200mg/kg ye diludine inowedzerwa muChikamu II kana ichienzaniswa neboka rezita.Uyezve, iyo ALP inowedzerwa pamwe nekuwedzera diludine yakawedzerwa kune kudya kwezuva nezuva, nepo tsika dzeALP muboka iro 150mg/kg uye 200mg/kg ye diludine yakawedzerwa yakakwirira kudarika boka rezita (p<0.05) zviri pachena.
Tafura 4 Migumisiro ye diludine pane serum parameters
| Huwandu hwe diludine huchawedzerwa (mg/kg) muChikamu I (30d) chebvunzo | ||||
| Item | 0 | 100 | 150 | 200 |
| Superoxide dismutase (mg/mL) |  | |||
| Uric acid | ||||
| Triglyceride (mmol/L) | ||||
| Lipase (U/L) | ||||
| Cholesterol (mg/dL) | ||||
| Glutamic-pyruvic transaminase (U/L) | ||||
| Glutamic-oxalacetic transaminase (U/L) | ||||
| Alkaline phosphatase (mmol/L) | ||||
| Calcium ion (mmol/L) | ||||
| Inorganic phosphorus (mg/dL) | ||||
| Huwandu hwe diludine huchawedzerwa (mg/kg) muChikamu II (80d) chebvunzo | ||||
| Item | 0 | 100 | 150 | 200 |
| Superoxide dismutase (mg/mL) |  | |||
| Uric acid | ||||
| Triglyceride (mmol/L) | ||||
| Lipase (U/L) | ||||
| Cholesterol (mg/dL) | ||||
| Glutamic-pyruvic transaminase (U/L) | ||||
| Glutamic-oxalacetic transaminase (U/L) | ||||
| Alkaline phosphatase (mmol/L) | ||||
| Calcium ion (mmol/L) | ||||
| Inorganic phosphorus (mg/dL) | ||||
3 Ongororo nekurukurirano
3.1 Iyo diludine muyedzo yakavandudza chiyero chekukandira, huremu hwezai, iyo Haugh unit uye huremu hwehuremu hwezai yolk, izvo zvakaratidza kuti diludine yaive nemhedzisiro yekusimudzira kubatanidzwa kweprotein uye kuvandudza huwandu hwekuumbwa kwegobvu. albumen yezai jena uye protein yezai yolk.Uyezve, zvinyorwa zveuric acid mu serum zvakaderedzwa zviri pachena;uye zvaiwanzobvumwa kuti kuderedzwa kwezvinyorwa zvisiri-protein nitrogen muserum zvaireva kuti catabolism speed yeprotein yakaderedzwa, uye nguva yekuchengetedza nitrogen yakamiswa.Ichi chigumisiro chakapa hwaro hwekuwedzera mapuroteni ekuchengetedza, kukurudzira kukandira mazai nekuvandudza huremu hwezai rehuku dzinokandira.Mhedzisiro yemuyedzo yakaratidza kuti iyo yekuisa mhedzisiro yakanaka apo 150mg/kg ye diludine yakawedzerwa, iyo yainyanya kuenderana nemhedzisiro.[6,7]yeBao Erqing neQin Shangzhi uye yakawanikwa nekuwedzera diludine panguva yekupedzisira yekukandira huku.Mhedzisiro yacho yakaderedzwa kana huwandu hwediludine hunopfuura 150mg/kg, izvo zvinogona kunge zviri nekuti mapuroteni shanduko.[8]yakakanganiswa nekuda kwekuwandisa dosage uye kuwandisa kwemetabolism yenhengo kune diludine.
3.2 Kuwanda kweCa2+mu seramu yezai rekuisa yakaderedzwa, iyo P muserum yakaderedzwa pakutanga uye basa reALP rakawedzerwa pachena muhupo hwe diludine, iyo yakaratidza kuti diludine yakakanganisa metabolism yeCa uye P zviri pachena.Yue Wenbin akataura kuti diludine inogona kukurudzira kunyura[9] ye mineral elements Fe uye Zn;ALP yainyanya kuvapo mumatishu, akadai sechiropa, bhonzo, mudumbu, itsvo, nezvimwewo;ALP muserum yaibva pachiropa nebhonzo kunyanya;ALP mubhonzo yaivepo muosteoblast kunyanya uye yaigona kusanganisa iyo phosphate ion neCa2 kubva muserum mushure mekushandurwa nekusimudzira kuparara kwephosphate uye kuwedzera kuwanda kweiyo phosphate ion, uye yakaiswa pabhonzo nenzira yehydroxyapatite, nezvimwe zvakadaro. . kuitira kutungamira mukuderedzwa kweCa uye P museramu, izvo zvinoenderana nekuwedzera kwegoko rezai ukobvu uye huremu hwegoko rezai muzviratidzo zvemhando yezai.Uyezve, iyo yakaputsika zai chiyero uye muzana yezai isina kujairika yakaderedzwa zviri pachena maererano nekuita kwekuisa, iyo yakatsanangurawo pfungwa iyi.
3.3 Kuiswa kwemafuta emudumbu uye chiropa chechiropa chehuku dzinokandira zvakaderedzwa zviri pachena nekuwedzera diludine mukudya, izvo zvakaratidza kuti diludine yakanga ine simba rekudzivirira synthesis yemafuta mumuviri.Uyezve, iyo diludine inogona kuvandudza basa re lipase mu serum mukutanga;basa re lipase rakawedzerwa zvakajeka muboka iro 100mg / kg ye diludine yakawedzerwa, uye zviri mukati me triglyceride uye cholesterol mu serum yakaderedzwa (p <0.01), iyo yakaratidza kuti diludine inogona kukurudzira kuora kwe triglyceride. uye kudzora synthesis yecholesterol.Kuiswa kwemafuta kunogona kudziviswa nekuti enzyme ye lipid metabolism muchiropa[10,11], uye kuderedzwa kwecholesterol muzai yolk yakatsanangurawo pfungwa iyi [13].Chen Jufang akashuma kuti diludine inogona kudzora kuumbwa kwemafuta mumhuka uye kuvandudza nyama yakaonda muzana yebroilers nenguruve, uye yakave nemhedzisiro yekurapa mafuta chiropa.Mhedzisiro yebvunzo yakajekesa iyi nzira yekuita, uye kuparadzaniswa uye kucherechedzwa kwemhedzisiro yehenzi yekuyedza yakaratidzawo kuti diludine inogona kuderedza kuitika kwechiropa chechiropa chehuku dzinokandira zviri pachena.
3.4 GPT neGOT zviratidzo zviviri zvakakosha zvinoratidza mashandiro echiropa nemoyo, uye chiropa nemoyo zvinogona kukuvadzwa kana mabasa acho akanyanya kukwirira.Mabasa eGPT neGOT muserum haana kuchinjwa pachena apo diludine yakawedzerwa mumuedzo, iyo yakaratidza kuti chiropa nemoyo hazvina kukuvara;mberi, chiyero chekuyera cheSOD chakaratidza kuti basa reSOD muserum rinogona kuvandudzwa zviri pachena kana diludine yakashandiswa kwenguva yakati.SOD inoreva scavenger yakakura ye superoxide yakasununguka radical mumuviri;iyo yakakosha pakuchengetedza kutendeseka kweiyo biological membrane, kuvandudza hutachiona hwehutachiona kugona uye kuchengetedza hutano hwemhuka kana zvirimo zveSOD mumuviri zvawedzerwa.Quh Hai, nezvimwewo zvakashuma kuti diludine inogona kuvandudza basa re6-glucose phosphate dehydrogenase mubhaibheri membrane uye kudzikamisa matishu [2] eiyo biological cell.Sniedze akataura kuti diludine yakadzora chiitiko [4] cheNADPH cytochrome C reductase zviri pachena mushure mekudzidza hukama pakati pe diludine uye enzyme yakakosha muNADPH chaiyo maelektronoti ekutamisa cheni mumakonzo chiropa microsome.Odydents yakaratidzawo kuti diludine yakanga yakabatana [4] kune composite oxidase system uye microsomal enzyme yakabatana neNADPH;uye maitiro ekuita kwe diludine mushure mekupinda mumhuka ndeyekuita basa rekudzivisa oxidation nekudzivirira biological membrane [8] nekudzivisa basa re electron transfer NADPH enzyme ye microsome uye kudzivisa peroxidation process ye lipid compound.Mhedzisiro yemuyedzo yakaratidza kuti basa rekudzivirira re diludine kune biological membrane kubva mukushandurwa kweSOD chiitiko kune shanduko yezviitiko zveGPT neGOT uye yakaratidza mhedzisiro yezvidzidzo zveSniedze neOdydents.
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Nguva yekutumira: Jun-07-2021