Kev yug me nyuam thiab kev txhim kho ntawm cov npua niaj hnub yog ua raws li tib neeg kev xav tau.Lub hom phiaj yog ua kom npua noj tsawg, loj hlob sai, tsim tau ntau thiab muaj cov nqaij ntshiv siab.Nws yog ib qho nyuaj rau ib puag ncig ntuj kom ua tau raws li cov kev cai no, yog li nws yog ib qho tsim nyog yuav tsum ua kom zoo hauv qhov chaw tsim khoom!

Kev khaws cia txias thiab cua sov, tswj cov av qhuav, dej phwj tuaj, huab cua zoo hauv tsev tsiaj nyeg, logistics system, pub khoom noj, khoom siv zoo, kev tswj ntau lawm, pub thiab khoom noj khoom haus, kev yug me nyuam technology thiab lwm yam cuam tshuam rau kev tsim khoom thiab kev noj qab haus huv ntawm cov khoom. npua.

Qhov xwm txheej tam sim no peb tab tom ntsib yog tias muaj kab mob npua ntau dua, ntau thiab ntau cov tshuaj tiv thaiv thiab tshuaj kho tsiaj, thiab nws nyuaj rau kev yug npua.Ntau tus npua teb tseem tsis tau txais txiaj ntsig lossis txawm tias poob thaum lub khw npua tau mus txog cov ntaub ntawv siab thiab kav ntev tshaj plaws.

Tom qab ntawd peb tsis tuaj yeem pab tab sis xav txog seb txoj hauv kev tam sim no los daws tus kab mob npua yog qhov tseeb lossis qhov kev taw qhia tsis raug.Peb yuav tsum xav txog cov hauv paus ntsiab lus ntawm tus kab mob hauv kev lag luam npua.Puas yog vim tus kab mob thiab cov kab mob muaj zog heev lossis kev cai lij choj ntawm npua tsis muaj zog?

Yog li tam sim no kev lag luam tau them nyiaj ntau dua thiab ntau dua rau qhov tsis muaj kev tiv thaiv kab mob ntawm npua!

Yam tseem ceeb cuam tshuam rau nonspecific tiv thaiv kev ua haujlwm ntawm npua:

1. Khoom noj khoom haus

Nyob rau hauv tus txheej txheem ntawm cov kab mob pathogenic, lub cev tiv thaiv kab mob ntawm cov tsiaj yog qhib, lub cev synthesizes ib tug loj tus naj npawb ntawm cytokines, tshuaj yam tseem ceeb, mob theem proteins, tiv thaiv kab mob, thiab lwm yam, lub metabolic tus nqi yog ho txhim khu kev qha, lub tshav kub ntau lawm thiab. lub cev kub yog nce, uas yuav tsum tau ntau cov as-ham.

Ua ntej, ntau cov amino acids xav tau los ua ke cov proteins, cov tshuaj tiv thaiv kab mob thiab lwm yam tshuaj nquag nyob rau theem mob, ua rau lub cev muaj protein ntau ntxiv thiab tso tawm nitrogen.Nyob rau hauv tus txheej txheem ntawm cov kab mob pathogenic, cov khoom ntawm cov amino acids feem ntau yog los ntawm degradation ntawm lub cev protein vim hais tias lub qab los noj mov thiab zaub mov noj ntawm cov tsiaj yog heev txo los yog txawm fasted.Txhim kho cov metabolism hauv inevitably nce qhov kev thov rau cov vitamins thiab kab kawm.

Ntawm qhov tod tes, qhov kev sib tw ntawm cov kab mob sib kis ua rau muaj kev ntxhov siab oxidative hauv cov tsiaj, ua rau ntau cov dawb radicals thiab nce kev noj cov tshuaj antioxidants (VE, VC, Se, thiab lwm yam).

Hauv kev sib tw ntawm cov kab mob sib kis, tsiaj txhu metabolism yog txhim kho, kev xav tau ntawm cov as-ham yog nce, thiab cov khoom noj khoom haus ntawm cov tsiaj hloov pauv los ntawm kev loj hlob mus rau kev tiv thaiv kab mob.Cov kev cuam tshuam metabolic ntawm cov tsiaj no yog tiv thaiv cov kab mob sib kis thiab muaj sia nyob ntau li ntau tau, uas yog qhov tshwm sim ntawm kev hloov mus sij hawm ntev lossis kev xaiv ntuj.Txawm li cas los xij, raws li kev xaiv khoom tsim, cov qauv metabolic ntawm npua hauv kev sib tw ntawm cov kab mob sib kis sib txawv los ntawm kev taug qab ntawm kev xaiv ntuj.

Nyob rau hauv xyoo tas los no, kev nce qib ntawm kev yug me nyuam npua tau txhim kho kev loj hlob ntawm npua thiab kev loj hlob ntawm cov nqaij ntshiv.Thaum cov npua no kis tau tus kab mob no, kev faib tawm ntawm cov khoom noj muaj txiaj ntsig hloov mus rau qee yam: cov as-ham faib rau lub cev tsis muaj zog thiab cov khoom noj uas tau faib rau kev loj hlob.

Raws li kev noj qab haus huv, qhov no yog ib qho txiaj ntsig zoo los txhim kho kev ua tau zoo (kev yug me nyuam npua yog ua raws li kev noj qab haus huv), tab sis thaum muaj kev sib tw los ntawm cov kab mob sib kis, cov npua no muaj kev tiv thaiv qis thiab kev tuag ntau dua li qub ntau yam (cov npua hauv zos hauv Suav teb loj hlob qeeb, tab sis lawv cov kab mob tiv thaiv ntau dua li niaj hnub npua txawv teb chaws).

Kev tsom mus rau qhov kev xaiv ntawm kev txhim kho kev loj hlob kev ua tau zoo tau hloov pauv cov kev faib tawm ntawm cov as-ham, uas yuav tsum tau txi lub luag haujlwm uas tsis yog kev loj hlob.Yog li ntawd, kev loj hlob npua ntshiv uas muaj peev xwm tsim tau siab yuav tsum muab cov khoom noj muaj txiaj ntsig zoo, tshwj xeeb tshaj yog nyob rau hauv kev sib tw ntawm cov kab mob sib kis, thiaj li ua kom cov khoom noj muaj txiaj ntsig zoo, kom muaj cov as-ham txaus rau kev txhaj tshuaj, thiab npua tuaj yeem kov yeej cov kab mob sib kis.

Nyob rau hauv cov ntaub ntawv ntawm cov dej qis ntawm kev yug npua los yog kev lag luam nyuaj hauv npua teb, txo cov khoom noj ntawm npua.Thaum tus kab mob sib kis tau tshwm sim, qhov tshwm sim yuav muaj kev puas tsuaj loj.

2. Kev nyuaj siab

Kev ntxhov siab rhuav tshem cov qauv mucosal ntawm npua thiab ua rau muaj kev pheej hmoo ntawm kev kis kab mob hauv npua.

Kev nyuaj siabua rau nce ntawm oxygen dawb radicals thiab rhuav tshem cov permeability ntawm cell membrane.Lub permeability ntawm cell membrane nce, uas yog ntau conducive mus rau cov kab mob nkag mus rau hauv lub hlwb;Kev ntxhov siab ua rau muaj kev zoo siab ntawm kev sib haum xeeb ntawm adrenal medullary system, txuas ntxiv ntawm cov hlab ntsha ntawm lub visceral, mucosal ischemia, hypoxic raug mob, rwj yaig;Kev ntxhov siab ua rau cov kab mob metabolic, nce cov kua qaub hauv lub cev thiab cov mucosal puas los ntawm cellular acidosis;Kev ntxhov siab ua rau muaj ntau ntxiv glucocorticoid secretion thiab glucocorticoid inhibits mucosal cell regeneration.

Kev ntxhov siab ua rau muaj kev pheej hmoo ntawm detoxification hauv npua.

Ntau yam kev ntxhov siab ua rau lub cev tsim cov pa oxygen dawb radicals ntau, uas ua rau cov hlab ntsha endothelial puas tsuaj, ua rau intravascular granulocyte aggregation, ua kom cov microthrombosis thiab endothelial cell puas, pab txhawb kev kis tus kab mob, thiab ua rau muaj kev pheej hmoo ntawm detoxification.

Kev ntxhov siab txo lub cev tsis kam thiab ua rau muaj kev pheej hmoo ntawm kev tsis ruaj khov hauv npua.

Ntawm ib sab, kev tswj hwm endocrine thaum muaj kev ntxhov siab yuav cuam tshuam lub cev tsis muaj zog, xws li glucocorticoid muaj kev cuam tshuam rau kev tiv thaiv kab mob;Ntawm qhov tod tes, qhov nce ntawm oxygen dawb radicals thiab pro-inflammatory yam tshwm sim los ntawm kev ntxhov siab yuav ua rau lub cev tsis muaj zog, ua rau txo qis ntawm cov kab mob hauv lub cev thiab tsis txaus tso tawm ntawm interferon, ua rau muaj kev tiv thaiv kab mob.

Cov tsos mob tshwj xeeb ntawm kev tiv thaiv kab mob tsis tshwj xeeb:

● Qhov muag excrement, kua muag me ntsis, rov qab los ntshav thiab lwm yam peb cov teeb meem qias neeg

Rov qab los ntshav, daim tawv nqaij laus thiab lwm yam teeb meem qhia tau hais tias lub cev thawj lub cev tiv thaiv kab mob, lub cev nto thiab mucosal barrier raug puas tsuaj, ua rau yooj yim nkag mus rau cov kab mob hauv lub cev.

Lub ntsiab lus ntawm lacrimal plaque yog tias lub caj pas lacrimal tsis tu ncua tso kua muag los tiv thaiv kev kis kab mob ntxiv los ntawm lysozyme.Lacrimal plaque qhia tau hais tias kev ua haujlwm ntawm lub cev tiv thaiv kab mob hauv zos ntawm lub qhov muag tau txo qis, thiab cov kab mob tsis tau raug tshem tawm tag nrho.Nws kuj tau pom tias ib lossis ob ntawm SIgA thiab ntxiv cov proteins hauv ocular mucosa tsis txaus.

● sow kev ua tau zoo degradation

Kev tshem tawm tus nqi khaws cia yog siab dhau lawm, cev xeeb tub sows rho menyuam, yug me nyuam, mummies, tsis muaj zog piglets, thiab lwm yam;

Lub sij hawm ntev estrous thiab rov qab mus rau estrus tom qab weaning;Cov kua mis zoo ntawm lactating sows poob qis, kev tiv thaiv ntawm cov menyuam yug tshiab piglets tsis zoo, kev tsim khoom qeeb, thiab raws plab tau siab.

Muaj cov kab mob mucosal nyob rau hauv txhua qhov mucosal ntawm cov noob, suav nrog lub mis, plab hnyuv, lub tsev menyuam, lub tsev menyuam, lub raum tubules, cov qog ntawm daim tawv nqaij thiab lwm yam submucosa, uas muaj ntau theem kev tiv thaiv kab mob tiv thaiv kab mob.

Siv lub qhov muag ua piv txwv:

① Ocular epithelial cell membrane thiab nws cov lipid secreted thiab dej Cheebtsam tsim lub cev tiv thaiv kab mob.

②Tshuaj tua kab mobCheebtsam secreted los ntawm cov qog nyob rau hauv ocular mucosal epithelium, xws li kua muag secreted los ntawm lacrimal qog, muaj ib tug loj npaum li cas ntawm lysozyme, uas yuav tua cov kab mob thiab inhibit cov kab mob kev loj hlob, thiab tsim ib tug tshuaj barrier rau pathogens.

③ Macrophages thiab NK natural killer hlwb muab faib rau hauv cov ntaub so ntswg ntawm cov mucosal epithelial hlwb tuaj yeem phagocytize cov kab mob thiab tshem tawm cov kab mob los ntawm cov kab mob, ua rau lub cev tiv thaiv kab mob.

④ Cov tshuaj tiv thaiv kab mob hauv zos yog tsim los ntawm immunoglobulin SIgA secreted los ntawm plasma hlwb faib rau hauv cov ntaub so ntswg ntawm subepithelial txheej ntawm ocular mucosa thiab ntxiv cov protein sib xws rau nws qhov ntau.

Hauv zosmucosal tiv thaiv kab mobplays lub luag haujlwm tseem ceeb hauvtiv thaiv kab mob, uas thaum kawg tuaj yeem tshem tawm cov kab mob, txhawb kev noj qab haus huv thiab tiv thaiv kab mob rov qab.

Cov tawv nqaij qub thiab kua muag me ntsis ntawm sows qhia qhov kev puas tsuaj ntawm tag nrho cov mucosal tiv thaiv!

Lub hauv paus ntsiab lus: kev noj zaub mov zoo thiab lub hauv paus ruaj khov;Kev tiv thaiv daim siab thiab detoxification los txhim kho kev noj qab haus huv;Txo kev ntxhov siab thiab ruaj khov ib puag ncig sab hauv;Kev txhaj tshuaj tsim nyog los tiv thaiv kab mob kis.

Vim li cas peb thiaj muab qhov tseem ceeb rau kev tiv thaiv daim siab thiab kev tshem tawm cov tshuaj lom hauv kev txhim kho kev tiv thaiv tsis tshwj xeeb?

Lub siab yog ib qho ntawm cov tswv cuab ntawm lub cev tiv thaiv kab mob.Innate lub cev tiv thaiv kab mob xws li macrophages, NK thiab NKT hlwb muaj ntau tshaj plaws hauv daim siab.Macrophages thiab lymphocytes nyob rau hauv daim siab yog tus yuam sij rau cellular tiv thaiv kab mob thiab humoral tiv thaiv raws li!Nws kuj yog lub hauv paus cell ntawm nonspecific tiv thaiv!Rau caum feem pua ​​​​ntawm macrophages hauv tag nrho lub cev sib sau ua ke hauv daim siab.Tom qab nkag mus rau hauv daim siab, feem ntau ntawm cov antigens ntawm txoj hnyuv yuav nqos thiab tshem tawm los ntawm macrophages (Kupffer hlwb) nyob rau hauv daim siab, thiab ib feem me me yuav raug ntxuav los ntawm lub raum;Tsis tas li ntawd, feem ntau ntawm cov kab mob, cov kab mob antigen antibody complexes thiab lwm yam teeb meem los ntawm cov ntshav ncig yuav raug nqos thiab tshem tawm los ntawm Kupffer hlwb kom tiv thaiv cov teeb meem no los ntawm kev puas tsuaj rau lub cev.Cov tshuaj lom uas ntxuav los ntawm daim siab yuav tsum tau tawm ntawm cov kua tsib mus rau txoj hnyuv, thiab tom qab ntawd tawm hauv lub cev los ntawm cov quav.

Raws li lub metabolic transformation chaw ntawm cov as-ham, daim siab plays lub luag hauj lwm irreplaceable nyob rau hauv lub smooth transformation ntawm as-ham!

Nyob rau hauv kev ntxhov siab, npua yuav ua rau kom cov metabolism thiab txhim kho lub peev xwm tiv thaiv kev ntxhov siab ntawm npua.Nyob rau hauv cov txheej txheem no, dawb radicals nyob rau hauv npua yuav nce heev, uas yuav ua rau kom lub nra ntawm npua thiab ua rau poob ntawm kev tiv thaiv.Kev tsim tawm ntawm cov dawb radicals yog qhov muaj txiaj ntsig zoo nrog kev siv zog ntawm cov metabolism hauv lub zog, uas yog, qhov muaj zog ntawm cov metabolism hauv lub cev, ntau cov dawb radicals yuav raug tsim.Qhov ntau zog ntawm cov metabolism hauv lub cev, qhov yooj yim dua thiab muaj zog dua lawv yuav raug tawm tsam los ntawm cov dawb radicals.Piv txwv li, lub siab muaj ntau yam enzymes, uas tsis tsuas yog koom rau hauv cov metabolism ntawm carbohydrates, proteins, rog, vitamins thiab cov tshuaj hormones, tab sis kuj muaj lub luag haujlwm ntawm detoxification, secretion, excretion, coagulation thiab tiv thaiv kab mob.Nws tsim cov dawb radicals ntau dua thiab muaj kev phom sij ntau dua los ntawm cov dawb radicals.

Yog li ntawd, txhawm rau txhim kho qhov tsis muaj kev tiv thaiv tshwj xeeb, peb yuav tsum ua tib zoo saib xyuas lub siab tiv thaiv thiab tshem tawm cov npua!