A na-eme ozuzu na nkwalite nke ezì nke oge a dịka mkpa mmadụ si dị.Ebumnuche bụ ime ka ezì na-eri obere nri, na-eto ngwa ngwa, na-emepụta ihe ma nwee anụ ahụ dị elu.O siri ike maka gburugburu ebe obibi imezu ihe ndị a chọrọ, ya mere ọ dị mkpa iji rụọ ọrụ nke ọma na gburugburu ebe obibi artificial!

The jụrụ na okpomọkụ ichekwa, akọrọ iru mmiri akara, nsị usoro, ikuku àgwà n'ime anụ ụlọ, lọjistik usoro, nri usoro, ngwá àgwà, mmepụta management, nri na oriri na ọṅụṅụ, ozuzu technology na ihe niile na-emetụta mmepụta arụmọrụ na ahụ ike ọnọdụ nke. ezi.

Ọnọdụ ugbu a anyị na-eche ihu bụ na a na-enwewanye ọrịa ezì, ọtụtụ ọgwụ mgbochi na ọgwụ anụmanụ, na ọ na-esiwanye ike ịzụlite ezì.Ọtụtụ ugbo ezì ka enweghị uru ma ọ bụ ọbụna mfu mgbe ahịa ezì erutela ihe ndekọ dị elu ma dị ogologo oge.

Mgbe ahụ, anyị enweghị ike inye aka ma tụgharịa uche na ma usoro ugbu a iji lụso ọrịa ezì ọgụ ọ̀ ziri ezi ma ọ bụ na ntụziaka ahụ adịghị mma.Anyị kwesịrị ịtụgharị uche na isi ihe kpatara ọrịa ahụ na ụlọ ọrụ ezì.Ọ bụ n'ihi na nje na nje bacteria siri ike ma ọ bụ iwu nke ezi adịghị ike?

Ya mere ugbu a, ụlọ ọrụ na-akwụ ụgwọ na-elebara anya na ọrụ mgbochi na-abụghị nke ezì!

Ihe ndị na-emetụta ọrụ mgbochi ezì na-enweghị isi:

1. Nri

N'ime usoro nke ọrịa pathogenic, a na-eme ka usoro ahụ ji alụso ọrịa ọgụ na-arụ ọrụ nke anụmanụ, ahụ na-emepụta ọnụ ọgụgụ dị ukwuu nke cytokines, ihe ndị na-emepụta kemịkalụ, protein na-egbuke egbuke, nje ndị na-alụso ọrịa ọgụ, wdg. okpomọkụ ahụ na-abawanye, nke na-achọ ọtụtụ nri.

Nke mbụ, a chọrọ ọnụ ọgụgụ buru ibu nke amino asịd iji synthesize protein, ọgwụ nje na ihe ndị ọzọ na-arụ ọrụ n'ime nnukwu oge, na-ebute mmụba protein anụ ahụ na nsị nitrogen.N'ime usoro nke ọrịa na-efe efe, ntinye nke amino acid na-esite na mmebi nke protein anụ ahụ n'ihi na agụụ na nri nke anụmanụ na-ebelata nke ukwuu ma ọ bụ ọbụna na-ebu ọnụ.Metabolism nke ọma ga-eme ka ọ dịkwuo mkpa maka vitamin na ihe ndị na-achọpụta ihe.

N'aka nke ọzọ, ihe ịma aka nke ọrịa na-efe efe na-eduga ná nrụgide oxidative na ụmụ anụmanụ, na-emepụta ọnụ ọgụgụ dị ukwuu nke free radicals na ịbawanye oriri nke antioxidants (VE, VC, Se, wdg).

N'ihe ịma aka nke ọrịa na-efe efe, a na-emeziwanye metabolism nke anụmanụ, na-abawanye mkpa maka nri na-edozi ahụ, na-agbanwe nkesa nri nke anụmanụ site na uto gaa na mgbochi.Mmeghachi omume metabolic ndị a nke anụmanụ bụ iguzogide ọrịa na-efe efe ma dị ndụ dị ka o kwere mee, nke sitere na evolushọn ogologo oge ma ọ bụ nhọrọ eke.Otú ọ dị, n'okpuru keakamere nhọrọ, na metabolic ụkpụrụ nke pigs na ihe ịma aka nke ọrịa na-efe efe deviates si track nke eke nhọrọ.

N'ime afọ ndị na-adịbeghị anya, ọganihu nke ịzụ anụ ezi emeela ka ọganihu nke ezì na-eto eto na mmụba nke anụ na-esighị ike.Ozugbo ezì ndị dị otú ahụ na-ebute ọrịa, usoro nkesa nke nri ndị dịnụ na-agbanwe ruo n'ókè ụfọdụ: ihe oriri ndị a na-ekenye maka usoro ahụ ji alụso ọrịa ọgụ na-ebelata na nri ndị e kenyere na-eto eto.

N'okpuru ọnọdụ ahụike, nke a bara uru n'ụzọ nkịtị iji melite arụmọrụ mmepụta (a na-eme ịzụ anụ ezi n'okpuru ọnọdụ ahụike siri ike), ma mgbe ọrịa na-efe efe na-ama ya aka, ezì dị otú ahụ nwere obere mgbochi na ọnwụ dị elu karịa ụdị ochie (ezi ndị dị na China na-eto nwayọọ nwayọọ, ma nguzogide ọrịa ha dị elu karịa ezì ndị mba ọzọ nke oge a).

Na-aga n'ihu na-elekwasị anya na nhọrọ nke imeziwanye arụmọrụ uto agbanweela nkesa nke ihe oriri na-edozi ahụ, nke ga-achụrịrị ọrụ ndị ọzọ karịa uto.Ya mere, ịzụ anụ ezi na-emepụta ihe dị elu ga-enye ọkwa nri dị elu, karịsịa na ihe ịma aka nke ọrịa ọrịa na-efe efe, iji hụ na ọkọnọ nke ihe oriri na-edozi ahụ, ka enwee nri zuru ezu maka ịgba ọgwụ mgbochi ọrịa, na ezì nwere ike imeri ọrịa na-efe efe.

N'ihe banyere obere tide nke ịzụ ezì ma ọ bụ ihe isi ike akụ na ụba na ugbo ezi, belata nri ezì.Ozugbo ọrịa ahụ malitere, ihe ga-esi na ya pụta nwere ike ịkpata ọdachi.

2. Nchegbu

Nchegbu na-ebibi usoro mucosal nke ezì ma na-abawanye ohere nke ibute ezì.

Nchegbuna-eduga na mmụba nke oxygen free radicals na-ebibi permeability nke cell membrane.Mwepu nke akpụkpọ ahụ cell mụbara, bụ nke na-eme ka nje bacteria banye n'ime sel;Nchegbu na-eduga ná mkpali nke sistemu medullary adrenal nke ọmịiko, mkpụkọ na-aga n'ihu nke arịa visceral, ischemia mucosal, mmerụ ahụ hypoxic, ọnya ọnya;Nchegbu na-eduga ná nsogbu metabolic, mmụba nke ihe intracellular acidic na mmebi mucosal nke cellular acidosis kpatara;Nchegbu na-eduga n'ịba ụba nke glucocorticoid secretion na glucocorticoid na-egbochi mmụgharị cell mucosal.

Nchegbu na-abawanye ohere nke detoxification na ezì.

Ihe dị iche iche na-akpata nchekasị na-eme ka ahụ nwee ike ịmepụta ọnụ ọgụgụ dị ukwuu nke oxygen free radicals, nke na-emebi sel endothelial vaskụla, na-ebute nchịkọta granulocyte intravascular, na-eme ka mmepụta microthrombosis na mmebi sel endothelial dịkwuo elu, na-eme ka mgbasa nke nje na-agbasa, na-abawanye ohere nke detoxification.

Nchegbu na-ebelata nkwụsị ahụ ma na-abawanye ohere nke enweghị ntụkwasị obi na ezì.

N'otu aka ahụ, usoro endocrine n'oge nrụgide ga-egbochi usoro ahụ ji alụso ọrịa ọgụ, dị ka glucocorticoid nwere mmetụta na-egbochi ọrụ mgbochi;N'aka nke ọzọ, mmụba nke radicals free oxygen na ihe ndị na-akpata mkpali nke nrụgide na-akpata ga-emebi kpọmkwem mkpụrụ ndụ ndị na-alụso ọrịa ọgụ, na-ebute mbelata nke ọnụ ọgụgụ nke mkpụrụ ndụ na-alụso ọrịa ọgụ na nzuzo nke interferon ezughị ezu, na-ebute immunosuppression.

Ngosipụta a kapịrị ọnụ nke mbelata mgbochi ọrịa na-abụghị nke akọwapụtara:

● nsị anya, ntụpọ anya mmiri, ọbara ọgbụgba azụ na nsogbu atọ ndị ọzọ ruru unyi

Ọbara ọgbụgba azụ, akpụkpọ ahụ ochie na nsogbu ndị ọzọ na-egosi na usoro ahụ ji alụso ọrịa ọgụ mbụ, elu ahụ na mgbochi mucosal mebiri emebi, na-eme ka ọ dị mfe ịbanye n'ime ahụ.

Isi ihe dị na plaque lacrimal bụ na gland lacrimal na-ezobe anya mmiri na-ezobe anya mmiri ka ọ ghara ibute ọrịa ọzọ site na lysozyme.Ihe ncheta lacrimal na-egosi na ọrụ nke mgbochi mgbochi mucosal mpaghara n'elu anya na-ebelata, ma ewepụbeghị nje ahụ kpamkpam.O gosikwara na otu ma ọ bụ abụọ nke SigA na protein ndị na-akwado na mucosa anya ezughi oke.

● Ghaaranụ mbelata arụmọrụ

Ọnụego mkpochapụ nke ịgha mkpụrụ akụ dị oke elu, ime na-akụ afọ ime, mụọ nwa nwụrụ anwụ, mummies, piglets adịghị ike, wdg;

Ogologo oge estrous dị ogologo ma laghachi na estrus mgbe a kwụsịrị ara;Ọdịdị mmiri ara ehi nke ịgha mkpụrụ na-enye nwa ara belatara, ihe mgbochi nke piglets amụrụ ọhụrụ adịghị mma, mmepụta ya adịghị ngwa ngwa, ọnụ ọgụgụ afọ ọsịsa dịkwa elu.

Enwere usoro mucosal na akụkụ mucosal niile nke ịgha mkpụrụ, gụnyere ara, tract digestive, akpanwa, traktị ọmụmụ, tubules gbasara akụrụ, glands anụ ahụ na submucosa ndị ọzọ, nke nwere ọrụ mgbochi mgbochi ọtụtụ ọkwa iji gbochie ọrịa nje.

Were anya dị ka ọmụmaatụ:

① Akpụkpọ anụ epithelial nke anya na lipid ya zoro ezo na akụkụ mmiri na-eme ihe mgbochi anụ ahụ nye ọrịa.

②Antibacterialihe ndị glands zoro ezo na epithelium mucosal anya, dị ka anya mmiri nke glands lacrimal zoro ezo, nwere nnukwu lysozyme, nke nwere ike igbu nje bacteria na igbochi mmeputakwa nje, na-abụkwa ihe mgbochi kemịkalụ na ọrịa nje.

③ Macrophages na mkpụrụ ndụ NK ekesa na-ekesa n'ime mmiri anụ ahụ nke mkpụrụ ndụ epithelial mucosal nwere ike phagocytize pathogens ma wepụ mkpụrụ ndụ ndị nje butere, na-eme ihe mgbochi sel mgbochi.

④ Mgbochi mucosal mpaghara bụ nke immunoglobulin SigA zoro ezo site na mkpụrụ ndụ plasma kesara n'ime anụ ahụ jikọtara nke subepithelial oyi akwa nke mucosa anya na protein na-akwado ya kwekọrọ na ọnụọgụ ya.

Mpagharamgbochi nke mucosalna-arụ ọrụ dị mkpa nanchebe nchebe, nke nwere ike mechaa kpochapụ ọrịa nje, na-akwalite mgbake ahụike ma gbochie ọrịa ugboro ugboro.

The ochie akpụkpọ na dọkatụrụ adọka tụrụ nke agha na-egosi mmebi nke mkpokọta mucosal mgbochi!

Ụkpụrụ: nri kwesịrị ekwesị na ntọala siri ike;Nchekwa imeju na nsị iji meziwanye ahụ ike;Belata nchekasị ma mee ka gburugburu ebe obibi guzosie ike;Ịgba ọgwụ mgbochi ọrịa nwere ezi uche iji gbochie ọrịa nje.

Kedu ihe kpatara anyị ji etinye mkpa na nchedo imeju na detoxification n'ịkwalite ihe mgbochi na-abụghị nke a kapịrị ọnụ?

Imeju bụ otu n'ime akụkụ nke sistemu mgbochi mgbochi.Mkpụrụ ndụ na-alụso ọrịa ọgụ dị ka macrophages, sel NK na NKT bụ nke kachasị na imeju.Macrophages na lymphocytes n'ime imeju bụ isi ihe na-eme ka ihe mgbochi cellular na mgbochi ihu ọchị n'otu n'otu!Ọ bụkwa sel bụ isi nke ihe mgbochi na-enweghị isi!Pasent iri isii nke macrophages na ahụ dum na-ezukọ na imeju.Mgbe ịbanye na imeju, ọtụtụ n'ime antigens sitere na eriri afọ ga-eloda ma kpochapụ site na macrophages (Cell Kupffer) n'ime imeju, a ga-ehichapụkwa obere akụkụ site na akụrụ;Na mgbakwunye, mkpụrụ ndụ Kupffer ga-eloda ma kpochapụ ọtụtụ n'ime nje virus, ogige antigen antigen na ihe ndị ọzọ na-emerụ ahụ site na mgbasa ọbara iji gbochie ihe ndị a na-emerụ ahụ imebi ahụ.Ihe mkpofu nsị nke imeju sachara kwesịrị ka e wepụ ya na bile n'ime eriri afọ, wee wepụ ya n'ahụ site na nsị.

Dị ka metabolic mgbanwe center nke nri, imeju na-arụ ọrụ a na-apụghị dochie anya na-eji ire ụtọ mgbanwe nke nri!

N'okpuru nrụgide, ezì ga-abawanye metabolism ma melite ikike mgbochi nrụgide nke ezì.Na usoro a, free radicals na pigs ga-amụba nke ukwuu, nke ga-eme ka ibu arọ nke ezì dịkwuo elu ma na-eduga ná nkwụsị nke mgbochi.A na-ejikọta mmepụta nke free radicals nke ọma na ike nke ume ike, ya bụ, ka usoro ahụ na-esiwanye ike, otú ahụ ka a ga-emepụta radicals n'efu.Ka metabolism nke akụkụ ahụ na-esiwanye ike, ka ọ dị mfe ma dị ike ka ndị free radicals ga-awakpo ha.Dịka ọmụmaatụ, imeju nwere enzymes dị iche iche, nke na-abụghị nanị na-ekere òkè na metabolism nke carbohydrates, protein, abụba, vitamin na hormones, ma na-enwekwa ọrụ nke detoxification, nzuzo, excretion, coagulation na mgbochi.Ọ na-emepụta radicals ndị ọzọ ma na-emerụ ahụ site na free radicals.

Ya mere, iji melite mgbochi na-abụghị kpọmkwem, anyị ga-aṅa ntị na nchebe imeju na detoxification nke ezì!