Kuweta ndi kukonza nkhumba zamakono kumachitika malinga ndi zosowa za anthu.Cholinga chake ndi kupanga nkhumba kudya pang'ono, kukula mofulumira, kutulutsa zambiri komanso kukhala ndi nyama yowonda kwambiri.Zimakhala zovuta kuti chilengedwe chikwaniritse zofunikirazi, choncho m'pofunika kuchita bwino m'malo opangira!

The kuzirala ndi kuteteza kutentha, youma kulamulira chinyezi, dongosolo zimbudzi, khalidwe mpweya mu nyumba ziweto, dongosolo mayendedwe, dongosolo chakudya, zida khalidwe, kasamalidwe kupanga, chakudya ndi zakudya, luso kuswana ndi zina zotero zimakhudza kupanga ntchito ndi chikhalidwe cha thanzi la nkhumba.

Zomwe tikukumana nazo pano ndikuti miliri ya nkhumba ikuchulukirachulukira, katemera wochulukirachulukira komanso mankhwala ochizira ziweto, ndipo ndizovuta kwambiri kuweta nkhumba.Mafamu ambiri a nkhumba akadalibe phindu kapena ngakhale kutayika pamene msika wa nkhumba wafika pamtunda wapamwamba ndipo unakhala motalika kwambiri.

Ndiye sitingachitire mwina koma kuganizira ngati njira yomwe ilipo panopa yothana ndi matenda a mliri wa nkhumba ndi yolondola kapena ngati njirayo ndi yolakwika.Tiyenera kuganizira zomwe zimayambitsa matendawa m'makampani a nkhumba.Kodi ndichifukwa chakuti kachilomboka ndi mabakiteriya ndi amphamvu kwambiri kapena kuti nkhumba ndi yofooka kwambiri?

Kotero tsopano makampani akuyang'anitsitsa kwambiri chitetezo chamthupi chomwe sichinali chenicheni cha nkhumba!

Zinthu zomwe zimakhudza chitetezo chamthupi mwa nkhumba:

1. Chakudya

M'kati mwa matenda opatsirana, chitetezo chamthupi cha nyama chimayatsidwa, thupi limapanga ma cytokines ambiri, zinthu zamagetsi, mapuloteni owopsa, ma antibodies a chitetezo chamthupi, etc. kutentha kwa thupi kumawonjezeka, zomwe zimafuna zakudya zambiri.

Choyamba, ma amino acid ambiri amafunikira kuti apange mapuloteni, ma antibodies ndi zinthu zina zogwira ntchito pachimake, zomwe zimapangitsa kuti thupi liwonongeke komanso kutulutsa nayitrogeni.M'kati mwa matenda opatsirana, kuperekedwa kwa amino acid makamaka kumachokera ku kuwonongeka kwa mapuloteni a thupi chifukwa chilakolako ndi kudya kwa nyama kumachepetsedwa kwambiri kapena kusala kudya.Kupititsa patsogolo kagayidwe kazakudya kudzawonjezera kufunikira kwa mavitamini ndi kufufuza zinthu.

Kumbali inayi, vuto la matenda a miliri limabweretsa kupsinjika kwa okosijeni mu nyama, kupanga kuchuluka kwa ma radicals aulere ndikuwonjezera kumwa kwa antioxidants (VE, VC, Se, etc.).

Pazovuta za matenda a mliri, kagayidwe ka nyama kakula, kufunika kwa zakudya kumawonjezeka, ndipo kagawidwe kazakudya ka nyama kumasinthidwa kuchoka pakukula kukhala chitetezo.Kagayidwe kachakudya kanyama kameneka kamakhala kolimbana ndi matenda a miliri ndikupulumuka momwe ndingathere, zomwe zimachitika chifukwa cha kusinthika kwanthawi yayitali kapena kusankhidwa kwachilengedwe.Komabe, posankhidwa mwachisawawa, kagayidwe kazakudya ka nkhumba pazovuta za matenda a mliri amapatuka panjira yosankha mwachilengedwe.

M'zaka zaposachedwa, kupita patsogolo koweta nkhumba kwathandizira kwambiri kukula kwa nkhumba komanso kukula kwa nyama yowonda.Nkhumba zotere zikagwidwa ndi kachilombo, kagawidwe ka zakudya zomwe zilipo zimasintha pang'onopang'ono: zakudya zomwe zimaperekedwa ku chitetezo cha mthupi zimachepa ndipo zakudya zomwe zimaperekedwa kuti zikule zimawonjezeka.

Pansi pa thanzi labwino, izi ndizopindulitsa mwachibadwa kupititsa patsogolo ntchito zopanga (kuweta nkhumba kumachitika pansi pa thanzi labwino), koma zikatsutsidwa ndi matenda a miliri, nkhumba zoterezi zimakhala ndi chitetezo chochepa komanso zimafa kwambiri kusiyana ndi mitundu yakale (nkhumba zam'deralo ku China zimakula pang'onopang'ono; koma kukana kwawo matenda ndikokwera kwambiri kuposa nkhumba zamakono zakunja).

Kukhazikika kosalekeza pakusankha kopititsa patsogolo kakulidwe kakukula kwasintha mwachibadwa kagawidwe kazakudya, zomwe zimayenera kupereka ntchito zina osati kukula.Chifukwa chake, kulera nkhumba zowonda ndi kuthekera kwakukulu kopanga kuyenera kupereka zakudya zopatsa thanzi, makamaka pazovuta za matenda a miliri, kuti zitsimikizire kupezeka kwa zakudya, kuti mukhale ndi zakudya zokwanira zoteteza katemera, komanso nkhumba zimatha kuthana ndi matenda a mliri.

Pakakhala kuchepa kwa mafunde a nkhumba kapena mavuto azachuma m'mafamu a nkhumba, chepetsani chakudya cha nkhumba.Mliriwu ukangoyamba, zotsatira zake zimakhala zoopsa kwambiri.

2. Kupsinjika maganizo

Kupsinjika maganizo kumawononga minyewa ya nkhumba ndikuwonjezera chiopsezo cha matenda a nkhumba.

Kupsinjika maganizokumabweretsa kuwonjezeka kwa oxygen free radicals ndikuwononga permeability ya cell membrane.Kuthekera kwa nembanemba yama cell kunakula, zomwe zidapangitsa kuti mabakiteriya alowe m'maselo;Kupanikizika kumabweretsa chisangalalo cha chifundo cha adrenal medullary system, kupindika kosalekeza kwa ziwiya za visceral, mucosal ischemia, kuvulala kwa hypoxic, kukokoloka kwa zilonda;Kupsinjika maganizo kumabweretsa kusokonezeka kwa kagayidwe kachakudya, kuwonjezeka kwa zinthu za acidic komanso kuwonongeka kwa mucosal chifukwa cha ma cell acidosis;Kupanikizika kumabweretsa kuchuluka kwa glucocorticoid ndipo glucocorticoid imalepheretsa kusinthika kwa maselo a mucosal.

Kupsyinjika kumawonjezera chiopsezo cha detoxification mu nkhumba.

Zinthu zosiyanasiyana zodetsa nkhawa zimapangitsa kuti thupi lipange ma radicals ambiri opanda okosijeni, omwe amawononga ma cell endothelial cell, kupangitsa kuti intravascular granulocyte aggregation, kufulumizitsa mapangidwe a microthrombosis ndi endothelial cell kuwonongeka, kumathandizira kufalikira kwa kachilomboka, ndikuwonjezera chiopsezo cha detoxification.

Kupanikizika kumachepetsa kukana kwa thupi komanso kumawonjezera chiopsezo cha kusakhazikika kwa nkhumba.

Kumbali imodzi, malamulo a endocrine panthawi yachisokonezo adzalepheretsa chitetezo cha mthupi, monga glucocorticoid ili ndi zotsatira zolepheretsa chitetezo cha mthupi;Kumbali ina, kuwonjezeka kwa okosijeni opanda ma radicals ndi zinthu zoyambitsa kutupa zomwe zimayambitsidwa ndi kupsinjika maganizo zidzawononga mwachindunji maselo a chitetezo cha mthupi, zomwe zimapangitsa kuchepa kwa maselo a chitetezo cha mthupi komanso kuchepa kwa interferon, zomwe zimapangitsa kuti chitetezo cha mthupi chitetezeke.

Mawonetseredwe enieni a kuchepa kwa chitetezo cha mthupi mosadziwika bwino:

● ndowe m’maso, madontho ong’ambika, kutuluka magazi m’mbuyo ndi mavuto ena atatu akuda

Back magazi, akale khungu ndi mavuto ena zimasonyeza kuti thupi loyamba chitetezo cha m`thupi, thupi pamwamba ndi mucosal chotchinga zawonongeka, chifukwa mosavuta kulowa tizilombo toyambitsa matenda m`thupi.

Chofunikira cha cholembera cha lacrimal ndikuti chotupa cha m'mphuno chimatulutsa misozi mosalekeza kuti tipewe kutenga tizilombo toyambitsa matenda kudzera mu lysozyme.Lacrimal zolengeza limasonyeza kuti ntchito m`deralo mucosal chitetezo chotchinga pa ocular padziko yafupika, ndipo tizilombotoyo sanachotsedwe kwathunthu.Zinawonetsanso kuti imodzi kapena ziwiri za SIgA ndi mapuloteni owonjezera mu mucosa wamaso anali osakwanira.

● kubzala kuwonongeka kwa ntchito

Mlingo wa kutha kwa nkhumba zosungirako ndizokwera kwambiri, nkhumba zoyembekezera zimachotsa mimba, zimabereka ana akufa, ma mummies, ana a nkhumba ofooka, ndi zina zotero;

Kutalika kwa estrous ndi kubwerera ku estrus pambuyo pa kuyamwa;Mkaka wa nkhumba zoyamwitsa unachepa, chitetezo cha ana obadwa kumene chinali chochepa, kubereka kunali kochepa, ndipo kutsekula m'mimba kunali kwakukulu.

Pali mucosal dongosolo lonse mucosal mbali zoweta, kuphatikizapo m`mawere, m`mimba thirakiti, chiberekero, ubereki thirakiti, aimpso tubules, tiziwalo timene timatulutsa khungu ndi submucosa zina, amene ali Mipikisano mlingo chitetezo chotchinga ntchito kupewa tizilombo toyambitsa matenda.

Tengani diso mwachitsanzo:

① Maselo a epithelial cell membrane ndi zigawo zake zobisika za lipid ndi madzi zimapanga chotchinga chakuthupi ku tizilombo toyambitsa matenda.

②Antibacterialzigawo zikuluzikulu zotulutsidwa ndi tiziwalo timene timatulutsa mu ocular mucosal epithelium, monga misozi yotulutsidwa ndi tiziwalo timene timatulutsa mphuno, imakhala ndi lysozyme yambiri, yomwe imatha kupha mabakiteriya ndikuletsa kuberekana kwa bakiteriya, ndikupanga chotchinga mankhwala ku tizilombo toyambitsa matenda.

③ Macrophages ndi NK masoka wakupha maselo anagawira mu minofu madzimadzi a mucosal epithelial maselo akhoza phagocytize tizilombo toyambitsa matenda ndi kuchotsa maselo amene ali ndi tizilombo toyambitsa matenda, kupanga chitetezo selo chotchinga.

④ Chitetezo cham'deralo cha mucosal chimapangidwa ndi immunoglobulin SIgA yotulutsidwa ndi maselo a plasma omwe amagawidwa mu minofu ya subpithelial ya ocular mucosa ndi mapuloteni ogwirizana ndi kuchuluka kwake.

Localmucosal chitetezoamatenga gawo lofunikira muchitetezo cha mthupi, zomwe pamapeto pake zimatha kuthetsa tizilombo toyambitsa matenda, kulimbikitsa thanzi labwino komanso kupewa matenda obwerezabwereza.

Akale khungu ndi misozi mawanga a nkhumba zimasonyeza kuwonongeka wonse mucosal chitetezo chokwanira!

Mfundo: zakudya zopatsa thanzi komanso maziko olimba;Chitetezo cha chiwindi ndi detoxification kuti ukhale wathanzi;Kuchepetsa kupsinjika ndi kukhazikika kwamkati mkati;Wololera katemera kuteteza tizilombo matenda.

Chifukwa chiyani timayika kufunikira kwa chitetezo cha chiwindi ndikuchotsa poizoni m'thupi pakuwongolera chitetezo chokwanira chomwe sichinatchulidwe?

Chiwindi ndi chimodzi mwa ziwalo za chitetezo cha mthupi.Maselo a chitetezo chamthupi monga macrophages, NK ndi NKT maselo ndi ochuluka kwambiri m'chiwindi.Macrophages ndi ma lymphocytes m'chiwindi ndiye chinsinsi cha chitetezo cham'manja komanso chitetezo cha humoral motsatana!Ndilonso selo loyambilira la chitetezo chamthupi chosadziwika bwino!Makumi asanu ndi limodzi pa zana aliwonse a macrophages m'thupi lonse amasonkhana m'chiwindi.Pambuyo polowa m'chiwindi, ma antigen ambiri ochokera m'matumbo adzamezedwa ndikutsukidwa ndi macrophages (maselo a Kupffer) m'chiwindi, ndipo gawo laling'ono lidzayeretsedwa ndi impso;Kuonjezera apo, mavairasi ambiri, mabakiteriya a antigen antibody complexes ndi zinthu zina zovulaza kuchokera m'magazi zidzamezedwa ndi kuyeretsedwa ndi maselo a Kupffer kuti ateteze zinthu zovulazazi kuti zisawononge thupi.Zinyalala zapoizoni zomwe zimatsukidwa ndi chiwindi zimafunika kuchotsedwa mu ndulu kupita m'matumbo, ndiyeno zimachotsedwa m'thupi ndi ndowe.

Monga malo osinthira kagayidwe kazakudya, chiwindi chimagwira ntchito yosasinthika pakusintha kosalala kwazakudya!

Pansi pa kupsinjika, nkhumba zimakulitsa kagayidwe kachakudya ndikuwongolera kuthekera kolimbana ndi kupsinjika kwa nkhumba.Pochita izi, ma radicals aulere mu nkhumba adzawonjezeka kwambiri, zomwe zidzawonjezera katundu wa nkhumba ndikupangitsa kuchepa kwa chitetezo chamthupi.Kupanga kwa ma free radicals kumayenderana bwino ndi mphamvu ya kagayidwe kazakudya, ndiko kuti, mphamvu ya kagayidwe kachakudya m'thupi, m'pamenenso ma free radicals amapangidwa.Kuchuluka kwamphamvu kwa kagayidwe ka ziwalo, ndikosavuta komanso kolimba kamene kadzawukiridwa ndi ma free radicals.Mwachitsanzo, chiwindi muli zosiyanasiyana michere, amene osati nawo kagayidwe kachakudya, mapuloteni, mafuta, mavitamini ndi mahomoni, komanso ntchito ya detoxification, katulutsidwe, excretion, coagulation ndi chitetezo chokwanira.Zimapanga ma free radicals ambiri ndipo zimawononga kwambiri ma free radicals.

Chifukwa chake, kuti tithandizire chitetezo chokwanira, tiyenera kulabadira chitetezo cha chiwindi ndikuchotsa nkhumba!