Ntau yam khoom siv tshuaj tua kab mob hauv kev tsim cov nqaij qaib yog maj mam raug txwv thoob ntiaj teb vim muaj teeb meem tsis zoo nrog rau cov tshuaj tua kab mob thiab cov tshuaj tua kab mob.Tributyrin yog lwm txoj hauv kev rau tshuaj tua kab mob.Cov txiaj ntsig ntawm txoj kev tshawb fawb tam sim no tau qhia tias tributyrin tuaj yeem txhim kho kev loj hlob ntawm kev ua haujlwm ntawm cov ntshav biochemical indices thiab cecal microflora muaj pes tsawg leeg ntawm daj-feathered broilers.Rau qhov zoo tshaj plaws ntawm peb txoj kev paub, ob peb txoj kev tshawb fawb tau tshawb xyuas qhov cuam tshuam ntawm tributyrin ntawm txoj hnyuv microbiota thiab nws txoj kev sib raug zoo nrog kev loj hlob ntawm cov nqaij qaib.Qhov no yuav muab lub hauv paus kev tshawb fawb rau kev siv tributyrin hauv kev yug tsiaj hauv lub sijhawm tom qab tshuaj tua kab mob.

Butyric acid yog tsim nyob rau hauv cov tsiaj plab hnyuv lumen los ntawm cov kab mob fermentation ntawm undigested noj carbohydrates thiab endogenous proteins.90% ntawm no butyric acid yog metabolized los ntawm cecal epithelial hlwb los yog colonocytes los muab ntau yam txiaj ntsig zoo rau lub plab noj qab haus huv.

Txawm li cas los xij, dawb butyric acid muaj cov ntxhiab tsw phem thiab nyuaj rau kev coj ua.Tsis tas li ntawd, cov dawb butyric acids tau pom tias muaj ntau absorbed nyob rau hauv lub plab hnyuv sab sauv, uas ua rau feem ntau tsis mus txog rau txoj hnyuv loj, qhov twg butyric acid yuav ua rau nws txoj haujlwm tseem ceeb.

Yog li ntawd, kev lag luam sodium ntsev butyrate tau tsim los kom yooj yim rau kev tuav thiab tiv thaiv kev tso tawm ntawm butyric acid nyob rau hauv lub plab hnyuv sab sauv.

Tab sis tributyrin muaj butyric acid thiab mono-butyrin thiab nyob rau hauv lub plab hnyuv sab sauv, tributyrin yog hydrolzed rau hauv butyric acid thiab α-mono-butyrin tab sis nyob rau hauv lub hindgut, lub loj molecule yuav α-monobutyrin uas muab ntau zog, rau txhawb kev loj hlob ntawm cov leeg nqaij thiab txhawb txoj kev loj hlob ntawm capillary rau kev thauj mus los zoo.

Muaj ntau yam kev tsis sib haum xeeb nrog rau lub plab noj qab haus huv ntawm qaib xws li:

• raws plab
• malabsorption syndrome
• coccidiosis
• necrotic enteritis

Qhov sib ntxiv ntawm tributyrin tau siv dav los tawm tsam plab hnyuv, thiab thaum kawg txhim kho nqaij qaib plab noj qab haus huv.

Nyob rau hauv txheej qaib hens, nws muaj peev xwm txhim kho calcium nqus nyob rau hauv tshwj xeeb tshaj yog nyob rau hauv cov laus nteg hens thiab txhim kho qe zoo.

Hauv piglets qhov kev hloov pauv hloov pauv yog lub sijhawm tseem ceeb vim muaj kev ntxhov siab hnyav los ntawm kev hloov ntawm cov kua rau cov khoom noj, hloov hauv ib puag ncig, thiab sib xyaw nrog cov cwj mem tshiab.

Hauv kev sim npua tsis ntev los no peb tau ua hauv Rivalea, nws tau qhia meej tias ntxiv 2.5 kg Tributyrin / MT tom qab noj zaub mov noj rau 35 hnub txhim kho lub cev hnyav nce los ntawm 5% thiab pub hloov pauv hloov pauv los ntawm 3 cov ntsiab lus.

Tributyrin kuj tseem siv tau rau hauv cov mis nyuj los hloov cov mis nyuj tag nrho thiab ua rau qee qhov cuam tshuam tsis zoo uas cov mis hloov mis muaj rau rumen txoj kev loj hlob.