Abincin abinci: Tributyrin

Abun ciki: 95%, 90%

Tributyrin azaman ƙari na abinci don kawo inganta lafiyar gut a cikin kaji.

Kashe maganin rigakafi a matsayin masu haɓaka haɓaka daga girke-girke na ciyar da kaji ya ƙara sha'awar wasu dabarun abinci mai gina jiki, don haɓaka aikin kiwon kaji tare da kariya daga rikice-rikicen cututtuka.

Rage rashin jin daɗi na dysbacteriosis
Don ci gaba da dubawa a kan yanayin dysbacteriosis, abubuwan da ake amfani da su kamar su probiotics da prebiotics ana ƙara su don tasiri ga samar da SCFAs, musamman butyric acid wanda ke taka muhimmiyar rawa wajen kare mutuncin hanji.Butyric acid shine SCFA da ke faruwa a zahiri wanda ke da fa'idodi masu fa'ida da yawa kamar tasirin sa na anti-mai kumburi, tasirin sa don hanzarta aiwatar da gyaran hanji da haɓaka haɓakar gut villi.Akwai wata hanya ta musamman da butyric acid ke aiki ta hanyar hana kamuwa da cuta, watau Host Defence Peptides (HDPs) synthesis, wanda kuma aka sani da peptides anti-microbial, waɗanda ke da mahimmancin abubuwan rigakafi na asali.Suna da babban aikin rigakafin ƙwayoyin cuta na ƙwayoyin cuta, fungi, parasites da ƙwayoyin cuta waɗanda ke da matukar wahala ga ƙwayoyin cuta su haɓaka juriya.Defensins (AvBD9 & AvBD14) da Cathelicidins sune manyan iyalai biyu na HDPs (Goitsuka et al.; Lynn et al.; Ganz et al.) da aka samu a cikin kaji wanda ke haɓakawa ta hanyar kariyar butyric acid.A wani bincike da Sunkara et.al.Exogenous gudanarwa na butyric acid yana haifar da karuwa mai ban mamaki a cikin maganganun kwayoyin HDP kuma don haka yana haɓaka ƙarfin jurewar cututtuka a cikin kaji.Abin sha'awa, matsakaici da LCFAs gefe.

Amfanin lafiya na Tributyrin
Tributyrin shine precursor na butyric acid wanda ke ba da damar ƙarin ƙwayoyin butyric acid don isar da su cikin ƙaramin hanji kai tsaye saboda fasahar esterification.Ta haka, abubuwan da aka tattara sun fi sau biyu zuwa uku fiye da samfuran da aka rufa.Esterification yana ba da damar ƙwayoyin butyric acid guda uku don ɗaure su zuwa glycerol waɗanda kawai za su iya karyewa ta lipase na pancreatic.
Li et.al.kafa wani nazarin rigakafi don nemo amfanin amfanin tributyrin akan cytokines masu kumburi a cikin broilers da aka kalubalanci LPS (lipopolysaccharide).An san amfani da LPS don haifar da kumburi a cikin karatu kamar wannan tunda yana kunna alamun kumburi kamar IL (Interleukins).A kwanakin 22, 24, da 26 na gwaji, an kalubalanci broilers tare da tsarin intraperitoneal na 500 μg / kg BW LPS ko saline.Kariyar tributyrin na abinci na 500 mg/kg ya hana haɓakar IL-1β & IL-6 yana ba da shawarar cewa kari zai iya rage sakin cytokines mai kumburi kuma don haka rage kumburin hanji.

Takaitawa
Tare da ƙayyadaddun amfani ko cikakken dakatarwa kan wasu masu haɓaka haɓakar ƙwayoyin cuta azaman abubuwan abinci, dole ne a bincika sabbin dabaru don haɓakawa da kare lafiyar dabbobin gona.Mutuncin hanji yana aiki azaman muhimmin mu'amala tsakanin albarkatun abinci masu tsada da haɓaka haɓakawa a cikin broilers.Butyric acid musamman ana gane shi azaman mai ƙarfi mai haɓaka lafiyar gastrointestinal wanda aka riga aka yi amfani dashi a cikin abincin dabbobi sama da shekaru 20.Tributyrindelivers butyric acid a cikin ƙananan hanji kuma yana da tasiri sosai wajen tasiri lafiyar hanji ta hanyar hanzarta aikin gyaran hanji, yana ƙarfafa haɓakar villi mafi kyau da kuma daidaita halayen rigakafi a cikin fili na hanji.

Yanzu tare da maganin rigakafi da ake cirewa, butyric acid babban kayan aiki ne don tallafawa masana'antu don rage mummunan tasirin dysbacteriosis wanda ke faruwa a sakamakon wannan canji.