Sodium butyrate yog ib qho organic compound nrog cov mis molecular C4H7O2Na thiab molecular hnyav ntawm 110.0869.Cov tsos yog dawb los yog yuav luag dawb hmoov, nrog ib tug tshwj xeeb cheesy rancid tsw thiab hygroscopic zog.Qhov ceev yog 0.96 g / mL (25/4 ℃), lub melting point yog 250-253 ℃, thiab nws yog yooj yim soluble nyob rau hauv dej thiab ethanol.

Sodium butyrate, raws li deacetylase inhibitor, tuaj yeem nce qib ntawm histone acetylation.Kev tshawb fawb tau pom tias sodium butyrate tuaj yeem cuam tshuam cov qog cell proliferation, txhawb qog cell aging thiab apoptosis, uas tej zaum yuav muaj feem xyuam rau qhov nce ntawm histone acetylation los ntawm sodium butyrate.Thiab sodium butyrate tau siv rau hauv kev tshawb fawb soj ntsuam ntawm cov qog.Nws tuaj yeem siv dav rau kev ntxiv tsiaj pub.

1. Tswj cov zej zog muaj txiaj ntsig microbial nyob rau hauv txoj hnyuv.Butyric acid inhibits kev loj hlob ntawm cov kab mob phem los ntawm cov cell membranes, txhawb kev loj hlob ntawm cov kab mob uas muaj txiaj ntsig zoo hauv txoj hnyuv, thiab tswj kev sib npaug zoo hauv plab hnyuv microbiota;
2. Muab cov khoom siv hluav taws xob ceev ceev rau cov kab mob hauv plab.Butyric acid yog lub zog nyiam ntawm cov hnyuv hauv plab, thiab sodium butyrate yog absorbed hauv plab hnyuv.Los ntawm oxidation, nws tuaj yeem muab lub zog sai rau cov hnyuv epithelial hlwb;
3. Txhawb kev loj hlob thiab kev loj hlob ntawm cov kab mob hauv plab.Lub plab zom mov ntawm cov menyuam yaus tsis tiav, nrog rau kev loj hlob ntawm cov plab hnyuv me thiab crypts, thiab tsis txaus tso tawm ntawm cov enzymes digestive, ua rau cov khoom noj tsis zoo ntawm cov menyuam yaus.Kev sim tau pom tias sodium butyrate yog ib qho activator uas txhim kho txoj hnyuv villus proliferation thiab crypt deepening, thiab tuaj yeem nthuav dav qhov nqus ntawm cov hnyuv loj;
4. Qhov cuam tshuam rau kev ua haujlwm ntawm cov tsiaj txhu.Sodium butyrate tuaj yeem ua rau muaj kev noj zaub mov ntau ntxiv, pub khoom noj, thiab nce qhov hnyav txhua hnub.Txhim kho tsiaj noj qab haus huv.Txo qhov mob raws plab thiab kev tuag;
5. Txhawb nqa kev ua haujlwm tsis yog thiab tshwj xeeb ntawm lub cev tiv thaiv kab mob;
6. Cov ntxhiab tsw tshwj xeeb muaj qhov ntxim nyiam ntxim nyiam rau cov tub ntxhais hluas npua thiab tuaj yeem siv los ua khoom noj khoom haus attractant;tuaj yeem ntxiv rau ntau hom kev pub noj kom nce qhov hnyav txhua hnub, noj kom tsawg, pub hloov pauv tus nqi, thiab txhim kho cov txiaj ntsig kev lag luam;
7. Txo qhov tso tawm ntawm intracellular Ca2+.Inhibiting histone deacetylase (HDAC) thiab inducing cell apoptosis;
8. Txhawb txoj kev loj hlob ntawm plab hnyuv mucosa, kho mucosal epithelial hlwb, thiab ua kom cov lymphocytes;
9. Txo cov ntshav qabzib tom qab noj mov hauv piglets, kov yeej kev ntxhov siab ntawm lub cev, thiab txhim kho piglet ciaj sia taus.