Ka lilemo tse mashome butyric acid e 'nile ea sebelisoa indastering ea phepelo ho ntlafatsa bophelo bo botle ba mala le ts'ebetso ea liphoofolo.Ho hlahisitsoe meloko e mengata e mecha ho ntlafatsa ts'ebetso ea sehlahisoa le ts'ebetso ea sona ho tloha ha liteko tsa pele li etsoa lilemong tsa bo-80.

Ka lilemo tse mashome butyric acid e 'nile ea sebelisoa indastering ea phepelo ho ntlafatsa bophelo bo botle ba mala le ts'ebetso ea liphoofolo.Meloko e mengata e mecha e hlahisitsoe ho ntlafatsa ts'ebetso ea sehlahisoa le ts'ebetso ea sona ho tloha ha liteko tsa pele li etsoa lilemong tsa bo-80.

1 Nts'etsopele ea asiti ea butyric joalo ka sehokelo sa phepelo

1980s > Butyric Acid e ne e sebediswa ho ntlafatsa ntshetsopele ya rumen
1990s> matsoai a butyrin acid a sebelisetsoang ntlafatso ea ts'ebetso ea liphoofolo
2000s> matsoai a koahetsoeng a ntlafalitse: ho fumaneha ha mala hantle le monko o fokolang
2010s> Asiti e ncha ea esterified le e sebetsang haholoanyane ea butyric e hlahisoa

Kajeno 'maraka o laoloa ke butyric acid e sirelelitsoeng hantle.Bahlahisi ba fepa ba sebetsang ka li-additives tsena ha ba na mathata ka litaba tsa monko mme phello ea li-additives ho bophelo bo botle ba mala le ts'ebetso e molemo.Bothata ba lihlahisoa tse tloaelehileng tse koahetsoeng ke leha ho le joalo ho fokotseha ha butyric acid.Hangata matsoai a koahetsoeng a na le 25-30% ea butyric acid, e tlaase haholo.

Nts'etsopele ea morao-rao ea li-additives tse thehiloeng ho butyric acid ke nts'etsopele ea ProPhorce™ SR: glycerol esters ea butyric acid.Li-triglycerides tsena tsa butyric acid ka tlhaho li ka fumanoa lebeseng le maheng a linotsi.Ke mohloli o sebetsang ka ho fetesisa oa asiti ea butyric e sirelelitsoeng ka bongata ba asiti ea butyric ho fihla ho 85%.Glycerol e na le sebaka sa ho ba le limolek'hule tse tharo tsa butyric acid tse hokelletsoeng ho eona ka se bitsoang 'ester bonds'.Likhokahano tsena tse matla li teng ho li-triglycerides tsohle 'me li ka robeha feela ka li-enzyme tse itseng (lipase).Sejalong le ka mpeng tributyrin e lula e tiile 'me ka maleng moo pancreatic lipase e fumanehang habonolo butyric acid e lokolloa.

Mokhoa oa esterifying butyric acid o ipakile e le mokhoa o sebetsang ka ho fetesisa oa ho etsa asiti ea butyric e se nang monko e lokolloang moo o e batlang: ka maleng.Phapang ka matsoai a koahetsoeng a thathamisitsoe ho feiga.2.

Ho ESPN ea bo20 Prague, thuto ea papiso e ile ea hlahisoa ka phello ea li-additives tse 2 tse fapaneng tsa butyric tse thehiloeng ho likhoho.Teko e ile ea etsoa setsing sa lipatlisiso sa ADAS UK ka 2014. Ba ile ba bapisa letsoai la sodium le koahetsoeng (le nang le 68% coating) le ProPhorce™ SR 130 (55% butyric acid).Litsuonyana tse 720 tsa Coss308 li ile tsa aroloa ka lihlopha tse 3, ka lipene tse 12 tsa linonyana tse 20 ka sehlopha.Ho etsisa maemo a khoebo ka hohle kamoo ho ka khonehang, litšila tse litšila li ile tsa eketsoa ka mor'a tlhahlobo ea likokoana-hloko, likokoana-hloko le likokoana-hloko.

Mosebetsi oa Tributyrin

1.Ho lokisa likokoana-hloko tse nyenyane tsa mala a liphoofolo le ho thibela libaktheria tse kotsi tsa mala.

2.E ntlafatsa ho monya le ho sebelisoa ha limatlafatsi.

3.E ka fokotsa lets'ollo le khatello ea maikutlo ea liphoofolo tse nyane.

4.E eketsa lebelo la ho phela le boima ba letsatsi le letsatsi ba liphoofolo tse nyenyane.