Sekungamashumi eminyaka i-butyric acid isetshenziswa embonini yokudla ukuze kuthuthukiswe impilo yamathumbu nokusebenza kwezilwane.Izizukulwane ezimbalwa ezintsha zethulwe ukuthuthukisa ukuphathwa komkhiqizo kanye nokusebenza kwawo kusukela ukuhlolwa kokuqala kwenziwa ngawo-80s.

Sekungamashumi eminyaka i-butyric acid isetshenziswa embonini yokudla ukuze kuthuthukiswe impilo yamathumbu nokusebenza kwezilwane.Izizukulwane ezimbalwa ezintsha zethuliwe ukuze kuthuthukiswe ukuphathwa komkhiqizo kanye nokusebenza kwawo kusukela ukuhlolwa kokuqala kwenziwa ngawo-80s.

1 Ukuthuthukiswa kwe-butyric acid njengesengezo sokudla

1980s > I-Butyric Acid yayisetshenziselwa ukuthuthukisa ukuthuthukiswa kwe-rumen
1990s> usawoti we-butyrin acid osetshenziselwa ukuthuthukiswa kokusebenza kwezilwane
2000s> usawoti oboshwe athuthukile: ukutholakala okungcono kwamathumbu kanye nephunga elincane
2010s> I-asidi entsha e-esterified nesebenza kahle kakhudlwana i-butyric

Namuhla imakethe ibuswa i-butyric acid evikelwe kahle.Abakhiqizi bokuphakelayo abasebenza nalezi zithako abanazo izinkinga ngezinkinga zephunga futhi umphumela wezithasiselo empilweni yamathumbu nokusebenza ungcono.Inkinga ngemikhiqizo evamile eboshwe nokho ukugcwala okuphansi kwe-butyric acid.Usawoti oboshwe ngokuvamile uqukethe i-25-30% ye-butyric acid, ephansi kakhulu.

Ukuthuthukiswa kwakamuva kwezithasiselo ezisekelwe ku-butyric acid okuphakelayo ukuthuthukiswa kwe-ProPhorce™ SR: i-glycerol esters ye-butyric acid.Lawa ma-triglycerides e-butyric acid ngokwemvelo angatholakala obisini noju.Ziwumthombo osebenza kahle kakhulu we-butyric acid evikelwe ene-butyric acid efika ku-85%.I-Glycerol inendawo yokuba nama-molecule amathathu e-butyric acid axhunywe kuyo ngalokho okubizwa ngokuthi 'amabhondi e-ester'.Lokhu kuxhumana okunamandla kukhona kuwo wonke ama-triglycerides futhi kungaphulwa kuphela ngama-enzyme athile (lipase).Esitshalweni nasesiswini i-tributyrin ihlala injalo futhi emathunjini lapho i-pancreatic lipase itholakala kalula khona i-butyric acid iyakhululwa.

Indlela yokwenza i-esterifying butyric acid ibonakale iyindlela ephumelela kakhulu yokudala i-butyric acid engenaphunga ekhishwa lapho uyifuna khona: emathunjini.Umehluko ngosawoti oboshwe ubhalwe kufig.2.

Ku-ESPN yama-20 ePrague, ucwaningo lokuqhathanisa lwethulwa ngomphumela wezithasiselo ezi-2 ezihlukene ezisekelwe ku-butyric acid kuma-broilers.Uhlolo lwenziwa esikhungweni socwaningo se-ADAS e-UK ngo-2014. Baqhathanisa usawoti we-sodium oboshiwe (onama-68% enamathela) ne-ProPhorce™ SR 130 (55% butyric acid).Amatshwele angama-720 e-Coss308 ahlukaniswa amaqoqo ama-3, anezibaya eziyi-12 zezinyoni ezingama-20 iqembu ngalinye.Ukulingisa izimo zezentengiselwano eduze ngangokunokwenzeka, udoti ongcolile wengezwa ngemva kokuhlolwa kwe-parasitological, bacterial and viral pathological.

Umsebenzi we-Tributyrin

1.Ilungisa i-villi yamathumbu amancane ezilwane futhi ivimbele amagciwane ayingozi amathumbu.

2.Ithuthukisa ukumuncwa kanye nokusetshenziswa kwemisoco.

3.Inganciphisa isifo sohudo kanye nengcindezi yokulunyulwa kwezilwane ezisencane.

4.Yenyusa izinga lokusinda kanye nokuzuza kwesisindo sansuku zonke sezilwane ezincane.