Sodium Butyrate kana tributyrin'ndoupi wokusarudza'?

Zvinowanzozivikanwa kuti butyric acid ndiyo yakakosha sosi yesimba kune colonic masero.Uyezve, ndiyo chaiyo inosarudzika peturu sosi uye inopa inosvika makumi manomwe muzana ezvese zvavanoda simba.Nekudaro, pane 2 mafomu ekusarudza kubva.Ichi chinyorwa chinopa kuenzanisa kwezvose zviri zviviri, zvichibatsira kupindura mubvunzo 'ndoupi wekusarudza'?

Kushandiswa kwemabutyrates sechiwedzerwa chekudya kwakadzidzwa zvakanyanya uye kushandiswa mukurima kwemhuka kwemakumi emakore akati wandei, ichitanga kushandiswa mumhuru kukurudzira kukura kwerumen kusati kwawana kushandiswa munguruve nehuku.

Butyrate additives yakaratidza kunatsiridza huremu hwemuviri (BWG) uye feed conversion rates (FCR), kuderedza kufa uye kuderedza kukanganiswa kwezvirwere zvine chekuita nehutumbu.

Anowanzo kuwanikwa masosi ebutyric acid yekudya kwemhuka inouya mumhando mbiri:

1. Somunyu (kureva Sodium butyrate) kana
2. Muchimiro che triglyceride (kureva Tributyrin).

Ipapo kunouya mubvunzo unotevera -Ndinosarudza chii?Ichi chinyorwa chinopa kudivi nedivi kuenzanisa kwezvose zviri zviviri.

Nzira yekugadzira

Sodium butyrate:Yakagadzirwa kuburikidza ne acid-base reaction kuita munyu une nzvimbo yakakwira yekunyungudika.

NaOH+C4 H8 O2=C4 H7 COONA+H2O

(Sodium Hydrooxide+Butyric Acid = Sodium Butyrate+Mvura)

Tributyrin:Yakagadzirwa kuburikidza ne esterification apo 3 butyric acid inosungirirwa kune glycerol kuti iite tributyrin.Tributyrin ine yakaderera kunyungudika.

C3H8O3+3C4H8O2= C15 H26 O6+3H2O

(Glycerol+Butyric Acid = Tributyrin + Mvura)

Ndeipi inopa yakawanda butyric acid pakg chigadzirwa?

KubvaTafura 1, tinoziva huwandu hweasidhi yebutyric iri muzvigadzirwa zvakasiyana.Nekudaro, isu tinofanirawo kufunga nezvekuti zvigadzirwa izvi zvinoburitsa butyric acid mumatumbo.Sezvo sodium butyrate iri munyu, inonyungudika nyore nyore mumvura inoburitsa butyrate, saka tinogona kufunga kuti 100% yebutyrate kubva sodium butyrate ichaburitswa kana yanyungudika.Sezvo sodium butyrate inoparadzaniswa nyore nyore, mafomu akadzivirirwa (kureva micro-encapsulation) yesodium butyrate inozoibatsira kuti iwane kuenderera kunononoka kuburitswa kwebutyrate mumatumbu kusvika kukoloni.

Tributyrin inonyanya kuita triacylglyceride (TAG), inova ester inotorwa kubva kuglycerol uye 3 fatty acids.Tributyrin inoda lipase kuti isunungure butyrate yakasungirirwa kune glycerol.Kunyangwe 1 tributyrin ine 3 butyrate, kwete ese matatu butyrate anovimbiswa kuburitswa.Izvi zvinodaro nekuti lipase is regioselective.Inogona hydrolyse triacylglycerides paR1 neR3, chete R2, kana isiri-chaiyo.Lipase inewo substrate chaiyo mukuti iyo enzyme inogona kusiyanisa pakati peacyl cheni dzakasungirirwa kune glycerol uye zviri nani kutsemura mamwe marudzi.Sezvo tributyrin ichida lipase kuburitsa butyrate yayo, panogona kunge paine kukwikwidza pakati pe tributyrin nemamwe maTAG e lipase.

Ko sodium butyrate uye tributyrin inokanganisa kudya kwekudya?

Sodium butyrate ine hwema hunogumbura husinganakidze vanhu asi hunofarirwa nemhuka dzinoyamwisa.Sodium butyrate accounts ye3.6-3.8% yemafuta emukaka mumukaka wezamu, saka, inogona kuita sechinhu chinokwezva chikafu chinokonzeresa kurarama kwekuzvarwa kwemhuka dzinoyamwisa (Tafura 2)Nekudaro, kuti uve nechokwadi chekuburitswa kunononoka mumatumbo, sodium butyrate inowanzovharirwa nemafuta matrix coating (kureva Palm stearin).Izvi zvinobatsirawo mukuderedza kunhuhwirira kwe sodium butyrate.

Tributyrin kune rumwe rutivi haina hwema asi ine astringent kuravira (Tafura 2)Kuwedzera huwandu hukuru kunogona kuve nemhedzisiro yakaipa pakudya kwekudya.Tributyrin imorekuru yakagadzikana inokwanisa kupfuura nepamusoro pegumbo remudumbu kusvika ratsemurwa ne lipase muura.Iyo zvakare haina-kuvhuvhuta pakudziya kwekamuri, saka kazhinji haina kuvharwa.Tributyrin kazhinji inoshandisa inert silica dioxide semutakuri wayo.Silica dioxide ine porous uye inogona kusaburitsa zvizere tributyrin panguva yekugaya.Tributyrin zvakare ine yakakwira mhute pressure ichiita kuti ive inoshanduka kana ichipisa.Naizvozvo, isu tinokurudzira kuti tributyrin ishandiswe ingave iri emulsified fomu kana mune yakachengetedzwa fomu.