Ukusetshenziswa kwe-organic acid kungathuthukisa ukusebenza kokukhula kwezinkukhu ezikhulayo nezingulube.Paulicks et al.(1996) wenze ukuhlolwa komthamo we-titration ukuze kuhlolwe umphumela wokwanda kwezinga le-potassium dicarboxylate ekusebenzeni kwezingulube ezikhulayo.0, 0.4, 0.8, 1.2, 1.6, 2.0, 2.4 kanye no-2.8%i-potassium dicarboxylatekwanezelwa ekuphakeleni kokuvula kwezingulube ezifunzwa ukudla okusekelwe kubhontshisi wesoya.Isilinganiso senzuzo yansuku zonke, ukudla kwansuku zonke kanye nezinga lokuguqulwa kokuphakelayo kweqembu le-potassium dicarboxylate likhuphuke ngo-13%, 9% no-4% ngokulandelana.Uma kuqhathaniswa neqembu elingalashwanga, ukungeza i-2% PD inyuse isisindo somzimba ngo-22%.Ngokwezinga eliphezulu lokungeza elibhaliswe yiziphathimandla zaseYurophu lika-1.8%, ukuzuza kwesisindo kunganyuswa ku-14%.Ukudla kwandiswe ngethamo elifanayo.Izinga lokuguqulwa kokuphakelayo (i-FCR) lehle ngokuhambisana nokukhuphuka kwe-PD, ukusuka ku-1.59 ukuya ku-1.47.Abanye abacwaningi bahlole umphumela we-PD ekusebenzeni kwezingulube.Ithebula 1 lifingqa imiphumela yokuhlolwa yemiphumela ye-PD ekuzuzeni isisindo (WG) ne-FCR.

Imithelela ye-potassium dicarboxylate ekuzuzeni isisindo sezilwane kanye nokuguqulwa kokuphakelayo

I-Potassium dicarboxylateibhaliswe njengomgqugquzeli wokukhula ongewona ama-antibiotic, okuhloswe ngawo ukufaka ama-antibiotic esikhundleni sokuphakelayo kanye nokuqinisekisa ukufinyelela kwabathengi emikhiqizweni ephephile.Ngakho-ke, izinzuzo zokusebenzisa i-potassium dicarboxylate kufanele ziqhathaniswe nemiphumela yokusetshenziswa okujwayelekile kwama-antibiotic okuphakelayo.I-Tylosin ingenye yemithi elwa namagciwane esetshenziswa kakhulu ezingulubeni.UDanielsen (1998) uqhathanise ukusebenza kokukhula kwezingulube eziphathwe ngama-antibiotic ukukhula umgqugquzeli we-tylosin noma i-PD.Imiphumela yabonisa ukuthi i-potassium dicarboxylate ingangena esikhundleni semithi elwa namagciwane ngaphandle kwanoma yimuphi umthelela omubi ekusebenzeni kwezilwane.Ucwaningo luye lwabonisa ukuthi i-potassium dicarboxylate ithuthukisa ukusebenza kokukhula kwezilwane, futhi ukusebenza kwe-antibacterial ye-potassium dicarboxylate kuyisici esiyinhloko esithinta ukusebenza kokukhula.

Umthelela wama-asidi e-organic ekusebenzeni kokukhula awuhlobene kuphela nomphumela omubi wama-asidi e-organic kuma-microorganisms, kodwa futhi nokunciphisa i-pH yamathumbu.Ngaphezu kwalokho, ama-ion angalungile e-asidi anomphumela omuhle ku-symbiosis yezitshalo zamathumbu.Yonke le miphumela inciphisa i-metabolism ephakathi futhi isiza ukuthuthukisa ukusebenza kokukhula.Ukwenziwa ngcono kokusetshenziswa kwezakhamzimba ngokwengxenye kungenxa yokuncipha kokuncintisana kwama-microbial for imisoco, kodwa futhi kuwumphumela wokugaya okusebenzayo kwe-enzyme kwezakhi.Roth et al.(I-1998) ibike ukuthi i-1.8% ye-PD supplementation ithuthukise ukugaya, ikakhulukazi kubonisa izinguquko zomsebenzi we-microbiota wamathumbu.Njengoba cishe u-80% we-nitrogen esendle uvela ezinambuzaneni, imiphumela yazo ibonisa ukuthi ukufakwa kwe-PD kunganciphisa inani lezakhi ezivubelayo ezingena ku-hindgut ngokwenza ngcono ukugayeka kwe-enzymatic emathunjini amancane.Baphinde baphakamisa ukuthi kungase kuthuthukise isimo sokucwila kwesidumbu ngokwenza ama-amino acids kube lula ukufaka amaprotheni emzimbeni.U-Partanene noMroz (1999) baveze ukuthi imithombo yamaprotheni yekhwalithi ephansi inomthelela omkhulu ekwenzeni ngcono ukugayeka kokudla amaprotheni kunemithombo yamaprotheni ekhwalithi ephezulu.

I-Potassium dicarboxylate ingathuthukisa ukuzuza kwesisindo sezilwane, ukudla okudliwayo kanye nokuguqulwa kokudla.Ukwenziwa ngcono kokusebenza kokukhula kulingana nalokho komgqugquzeli wokukhula.Ngakho-ke, i-potassium dicarboxylate isibe indawo ephumelelayo yama-antibiotic okuphakelayo ngenxa yezakhiwo zayo ezinhle kakhulu.Umthelela ku-microflora ubhekwa njengendlela eyinhloko yesenzo, futhi ayikho ingozi yokumelana ne-microbial.Yehlisa izinga le-E. coli ne-Salmonella emikhiqizweni yenyama.