Potassium formate, yekutanga isiri antibiotic feed additive yakabvumidzwa neEuropean Union muna 2001 uye yakatenderwa neBazi rezvekurima reChina muna 2005, yakaunganidza hurongwa hwekunyorera hwakakura kwemakore anopfuura gumi, uye mapepa akawanda ekutsvagisa mukati nekunze kwenyika akataura mhedzisiro yawo. pamatanho akasiyana-siyana ekukura kwenguruve.

Necrotizing enteritis chirwere chepasi rose chehuku chinokonzerwa ne gram-positive bacteria (Clostridium perfringens), icho chichawedzera kufa kwebroilers uye kuderedza kukura kwehuku nenzira shoma.Zvose izvi zvinokanganisa hutano hwemhuka uye zvinounza kurasikirwa kukuru kwehupfumi pakugadzirwa kwehuku.Mukugadzirwa chaiko, mishonga inorwisa mabhakitiriya inowanzowedzerwa kudyisa kudzivirira kuitika kwe necrotizing enteritis.Nekudaro, kushevedzera kwekurambidzwa kwemishonga inorwisa mabhakitiriya mukudya kuri kuwedzera, uye dzimwe mhinduro dzinodiwa kutsiva mhedzisiro yekudzivirira yemishonga.Chidzidzo chacho chakawana kuti kuwedzera organic acids kana munyu wavo mukudya kunogona kuvharidzira zviri muClostridium perfringens, nokudaro zvichideredza kuitika kwenecrotizing enteritis.Potassium formate inonyungudutswa kuita formic acid uye potassium formate muura.Nekuda kweiyo covalent bond pfuma kune tembiricha, imwe formic acid inopinda zvachose muura.Kuedza uku kwakashandisa huku ine necrotizing enteritis semuenzaniso wekutsvagisa kuongorora mhedzisiro yepotassium formatepakukura kwayo kuita, intestinal microbiota, uye short chain fatty acid content.

1. Mhedzisiro yePotassium DiformatepaKukura Kwekuita kweBroiler Dzinotapukirwa neNecrotizing Enteritis.

Mhedzisiro yekuedza yakaratidza kuti potassium formate yakanga isina mhedzisiro yakakura pakukura kwebroilers ine kana isina necrotizing enteritis utachiona, izvo zvinoenderana nemhedzisiro yekutsvaga yaHernandez et al.(2006).Zvakaonekwa kuti muyero mumwechete we calcium formate wakanga usina chinhu chakakosha pakukura kwemazuva ose uye chiyero chekudya kwebroilers, asi apo kuwedzerwa kwe calcium formate kwakasvika 15 g / kg, zvakanyanya kuderedza kukura kwekukura kwebroilers (Patten naWaldroup). , 1988).Zvisinei, Selle et al.(2004) akawana kuti kuwedzera 6 g/kg ye potassium formate pakudya kwakawedzera kuwedzera uremu uye kudya kwehuku dzebroiler nemazuva 16-35.Ikozvino kune mishumo mishoma yekutsvagisa nezve basa re organic acids mukudzivirira necrotizing enteritis utachiona.Ichi chiedzo chakawana kuti kuwedzera 4 g/kg potassium formate pakudya kwakaderedza zvakanyanya kufa kwebroilers, asi pakanga pasina hukama hwekuita-dose pakati pekuderedzwa kwehuwandu hwekufa uye huwandu hwe potassium fomati yakawedzerwa.

2. Mhedzisiro yePotassium Diformatepamusoro peMicrobial Content muTissues uye Organs of Broilers Inotapukirwa neNecrotizing Enteritis.

Kuwedzerwa kwe45mg/kg bacitracin zinc muzvokudya kwakaderedza kufa kwebroilers vane utachiona necrotizing enteritis, uye panguva imwechete yakaderedza zvinyorwa zveClostridium perfringens mujejunum, iyo yaienderana nemigumisiro yekutsvakurudza yaKocher et al.(2004).Ikoko kwakanga kusina kukosha kwekudya kwe potassium diformate supplementation pane zvinyorwa zveClostridium perfringens mujejunum yebroilers yakabatwa necrotizing enteritis kwemazuva gumi nemashanu.Walsh et al.(2004) akawana kuti kudya kwakanyanya kweasidhi kune mhedzisiro yakaipa pane organic acids, saka, iyo yakakwira acidity yeakakwira mapuroteni kudya inogona kuderedza kudzivirira kwe potassium formate pane necrotizing enteritis.Ichi chiedzo chakawanawo kuti potassium formate yakawedzera zviri mukati lactobacilli mudumbu remhasuru ye35d broiler huku, izvo zvisingaenderane neKnarreborg et al.(2002) kuwana in vitro kuti potassium formate yakaderedza kukura kwe lactobacilli mudumbu renguruve.

3.Mhedzisiro ye potassium 3-dimethylformate pane tishu pH uye pfupi chain fatty acid zviri mukati mehuku dzebroiler dzakatapukirwa necrotizing enteritis.

Iyo antibacterial mhedzisiro ye organic acids inotendwa kuti inonyanya kuitika muchikamu chepamusoro chechikamu chekudya.Mhedzisiro yekuyedza iyi yakaratidza kuti potassium dicarboxylate yakawedzera iyo formic acid muduodenum pamazuva gumi nemashanu uye jejunum pamazuva makumi matatu nemashanu.Mroz (2005) akaona kuti pane zvakawanda zvinokanganisa kuita kweorganic acids, senge feed pH, buffering/acidity, uye dietary electrolyte balance.Low acidity uye yakakwira electrolyte balance mukudya inogona kukurudzira kuparadzaniswa kwe potassium fomati kuita formic acid uye potassium fomati.Naizvozvo, mwero wakakodzera we acidity uye electrolyte kuenzanisa kukosha mukudya kunogona kusimudzira kuvandudzwa kwekukura kwebroilers ne potassium fomati uye kudzivirira kwayo kune necrotizing enteritis.

Mhedziso

Migumisiro yepotassium formatepamuenzaniso we necrotizing enteritis muhuku dzebroiler yakaratidza kuti potassium formate inogona kuderedza kuderera kwekukura kwehuku dzebroiler pasi pemamwe mamiriro nekuwedzera uremu hwemuviri uye kuderedza kufa, uye inogona kushandiswa sekuwedzera kwekudya kudzora hutachiona hwe necrotizing enteritis mu huku dzebroiler.