Potassium formate, tlatsetso ea pele e seng ea lithibela-mafu e amohetsoeng ke European Union ka 2001 mme e amohetsoe ke Lekala la Temo la China ka 2005, e bokelletse leano la kopo e seng e hōlile ka lilemo tse fetang 10, 'me lipampiri tse ngata tsa lipatlisiso ka hare ho naha le machabeng li tlalehile litlamorao tsa eona. ka mekhahlelo e fapaneng ea kholo ea likolobe.

Necrotizing enteritis ke lefu la lefatshe la dikgoho le bakwang ke baktheria ya gram-positive (Clostridium perfringens), e tla eketsa ho shwa ha ditsuonyana le ho fokotsa tshebetso ya kgolo ya dikgoho ka mokgwa o fokolang.Liphetho tsena ka bobeli li senya boiketlo ba liphoofolo le ho tlisa tahlehelo e kholo ea moruo tlhahisong ea likhoho.Tlhahisong ea 'nete, lithibela-mafu hangata li eketsoa ho fepa ho thibela ho hlaha ha necrotizing enteritis.Leha ho le joalo, pitso ea thibelo ea lithibela-mafu lijong e ntse e eketseha, 'me ho hlokahala litharollo tse ling ho nka sebaka sa thibelo ea lithibela-mafu.Boithuto bona bo fumane hore ho kenyelletsa organic acid kapa matsoai a bona lijong ho ka thibela litaba tsa Clostridium perfringens, ka hona ho fokotsa ho hlaha ha necrotizing enteritis.Potassium formate e aroloa ho ba formic acid le potassium formate ka maleng.Ka lebaka la thepa ea covalent bond ho mocheso, ba bang ba formic acid e kena ka ho feletseng ka maleng.Teko ena e sebelisitse khoho e tšoaelitsoeng ke necrotizing enteritis e le mohlala oa lipatlisiso ho batlisisa liphello tsasebopeho sa potasiamomabapi le ts'ebetso ea eona ea kholo, intestinal microbiota, le litaba tse khutšoane tsa mafura a acid.

1. Phello eaPotassium Diformatemabapi le Keketseho ea Ts'ebetso ea Likhoho tsa nama tse tšoaelitsoeng ke Necrotizing Enteritis.

Liphetho tsa liteko li bonts'itse hore sebopeho sa potassium ha se na phello e kholo ts'ebetsong ea kholo ea likhoho tse nang le tšoaetso ea enteritis kapa ntle le necrotizing, e lumellanang le liphetho tsa lipatlisiso tsa Hernandez et al.(2006).Ho ile ha fumanoa hore tekanyo e tšoanang ea khalsiamo formate ha e na phello e kholo ho boima ba letsatsi le letsatsi le karolelano ea lijo tsa likhoho, empa ha ho eketsoa ha calcium formate ho fihla ho 15 g/kg, ho ile ha fokotsa haholo ts'ebetso ea kholo ea likhoho (Patten le Waldroup). , 1988).Leha ho le joalo, Selle et al.(2004) e fumane hore ho eketsa 6 g/kg ea potassium formate ho lijo ho ile ha eketsa boima ba 'mele le ho ja likhoho tsa broiler ka matsatsi a 16-35.Hona joale ho na le litlaleho tse fokolang tsa lipatlisiso mabapi le karolo ea organic acid ho thibela tšoaetso ea necrotizing enteritis.Teko ena e fumane hore ho kenyelletsa 4 g/kg ea potassium formate lijong ho fokolitse sekhahla sa ho shoa ha likhoho tsa nama, empa ho ne ho se na kamano ea lethal dose lipakeng tsa phokotso ea sekhahla sa ho shoa le palo ea potassium e kenyellelitsoeng.

2. Phello eaPotassium Diformatemabapi le Microbial Content in Tissues le Organs of Broilers tse tšoaelitsoeng ke Necrotizing Enteritis

Ho eketsoa ha zinki ea bacitracin ea 45mg / kg ho fepa ho fokolitse ho shoa ha likhoho tse tšoaelitsoeng ke necrotizing enteritis, 'me ka nako e ts'oanang ho fokotsa litaba tsa Clostridium perfringens ka jejunum, e neng e lumellana le liphello tsa lipatlisiso tsa Kocher et al.(2004).Ha hoa ka ha e-ba le phello e kholo ea tlatsetso ea potassium diformate ka har'a litaba tsa Clostridium perfringens ho jejunum ea likhoho tse tšoaelitsoeng ke necrotizing enteritis ka matsatsi a 15.Walsh et al.(2004) e fumane hore lijo tse nang le acidity e ngata li na le phello e mpe ho li-organic acid, ka hona, acidity e phahameng ea lijo tse nang le protheine e ngata e ka fokotsa phello ea thibelo ea potassium formate ho necrotizing enteritis.Teko ena e boetse e fumane hore sebopeho sa potassium se ekelitse litaba tsa lactobacilli ka mpeng ea mesifa ea likhoho tsa broiler tse 35d, tse sa lumellaneng le Knarreborg et al.(2002) ho fumana in vitro hore potassium formate e fokolitse kholo ea lactobacilli ka mpeng ea kolobe.

3.Phello ea potassium 3-dimethylformate ho pH ea lisele le li-acid tse khutšoane tsa mafura a mafura ka har'a likhoho tsa broiler tse tšoaelitsoeng ke necrotizing enteritis.

Ho lumeloa hore phello ea antibacterial ea organic acid e etsahala haholo karolong e ka holimo ea tšilo ea lijo.Liphetho tsa liteko tsena li bonts'itse hore potassium dicarboxylate e ekelitse boemo ba acid e formic ka duodenum ka matsatsi a 15 le jejunum ka matsatsi a 35.Mroz (2005) o fumane hore ho na le lintlha tse ngata tse amang ketso ea li-organic acid, tse kang phepelo pH, buffering/acidity, le dietary electrolyte balance.Asiti e tlase le litekanyetso tse phahameng tsa electrolyte lijong li ka khothaletsa karohano ea sebopeho sa potassium hore e be formic acid le potassium formate.Ka hona, boemo bo nepahetseng ba acidity le litekanyetso tsa electrolyte lijong li ka ntlafatsa ntlafatso ea ts'ebetso ea kholo ea likhoho ka sebopeho sa potasiamo le phello ea eona ea thibelo ho necrotizing enteritis.

Qetello

Liphetho tsasebopeho sa potasiamoka mohlala oa necrotizing enteritis ka likhoho tsa broiler e bontšitse hore potassium formate e ka fokotsa ho fokotseha ha ts'ebetso ea kholo ea likhoho tsa broiler tlas'a maemo a itseng ka ho eketsa boima ba 'mele le ho fokotsa ho shoa,' me e ka sebelisoa e le sehlomathiso sa phepelo ho laola tšoaetso ea necrotizing enteritis. likhoho tsa broiler.