Potassium formate, wax lagu daro quudinta antibiyootiga ugu horeysay ee ay ansixiyeen Midowga Yurub 2001 oo ay ansixiyeen Wasaaradda Beeraha ee Shiinaha 2005, waxay ururisay qorshe codsi ah oo qaan-gaar ah muddo ka badan 10 sano, iyo waraaqo cilmi-baaris oo badan oo gudaha iyo dibaddaba ah ayaa soo sheegay saameynteeda. marxaladaha kala duwan ee koritaanka doofaarka.

Necrotizing enteritis waa cudur digaaga oo caalami ah oo ay keento bakteeriyada garaam-positive (Clostridium perfringens), taas oo kordhin doonta dhimashada broilers iyo hoos u dhigi doonaa waxqabadka koritaanka digaagga hab hoose.Labadan natiijadoodba waxay dhaawacaan daryeelka xoolaha waxayna khasaare dhaqaale oo weyn u geystaan ​​wax-soo-saarka digaagga.Wax soo saarka dhabta ah, antibiyootiga ayaa inta badan lagu daraa quudinta si looga hortago in ay dhacdo necrotizing enteritis.Si kastaba ha ahaatee, baaqa mamnuucista antibiyootiga ee quudinta ayaa sii kordhaya, xalal kale ayaa loo baahan yahay si loo beddelo saameynta ka hortagga antibiyootiga.Daraasadu waxay ogaatay in cuntada lagu daro asiidhyada organic ama milixdooda ay xannibi karto waxa ku jira Clostridium perfringens, taas oo hoos u dhigaysa dhacdooyinka necrotizing enteritis.Potassium formate wuxuu u kala go'ay oo u kala baxa formic acid iyo potassium formate ee xiidmaha.Iyada oo ay ugu wacan tahay hantida dammaanadda isku xidhka ee heerkulka, qaar ka mid ah aashitada formic ayaa si buuxda u gasha xiidmaha.Tijaabadani waxay isticmaashay digaaga qaba cudurka necrotizing enteritis sida moodal cilmi baaris si loo baaro saameyntaqaabka potassiumon waxqabadka koritaanka, microbiota mindhicirka, iyo silsilad gaaban dufanka content content.

1. SaamayntaPotassium DiformateWaxqabadka Kobaca ee Broilers-ka uu ku dhacay Necrotizing Enteritis.

Natiijooyinka tijaabada ah waxay muujiyeen in qaabka potassium uusan saameyn weyn ku yeelan waxqabadka koritaanka broilers leh ama aan lahayn necrotizing infekshanka enteritis, taas oo la socota natiijooyinka cilmi-baarista Hernandez et al.(2006).Waxaa la ogaaday in isla qiyaasta kalsiyumku aysan saameyn weyn ku yeelan miisaanka maalinlaha ah iyo saamiga quudinta ee broilers, laakiin marka lagu daro qaabka kalsiyumku ay gaartay 15 g / kg, waxay si weyn hoos ugu dhigtay waxqabadka koritaanka broilers (Patten iyo Waldroup). , 1988).Si kastaba ha ahaatee, Selle et al.(2004) waxay ogaatay in cuntada lagu daro 6 g/kg oo ah potassium formate si aad ah u kordhisay korodhka miisaanka iyo quudinta digaagga broiler 16-35 maalmood.Hadda waxaa jira warbixino yar oo cilmi baaris ah oo ku saabsan doorka acids organic ka hortagga necrotizing caabuqa enteritis.Tijaabadani waxay ogaatay in lagu daro 4 g/kg potassium formate ee cuntada si aad ah u hoos u dhigtay heerka dhimashada ee broilers, laakiin ma jirin xidhiidh saameyneed oo u dhexeeya dhimista heerka dhimashada iyo qadarka qaabka potassium ee lagu daray.

2. SaamayntaPotassium DiformateWaxyaabaha ku jira Microbial ee ku jira unugyada iyo xubnaha Broilers ee uu ku dhacay cudurka necrotizing enteritis

Ku darida 45mg / kg bacitracin zinc ee quudinta ayaa hoos u dhigtay dhimashada broilers ee qaba cudurka necrotizing enteritis, isla markaana waxay hoos u dhigtay maadada Clostridium perfringens ee jejunum, taas oo la socota natiijooyinka cilmi-baarista ee Kocher et al.(2004).Ma jirin wax saamayn ah oo la taaban karo oo kaabista potassium diformate-ka cuntada ee nuxurka Clostridium perfringens ee jejunum ee broilers cudurka qaba necrotizing enteritis muddo 15 maalmood ah.Walsh iyo al.(2004) waxay ogaatay in cuntooyinka aysidhka ah ee sarreeya ay saameyn xun ku yeeshaan asiidhyada organic, sidaas darteed, aashitada sare ee cuntooyinka borotiinka sare waxay yareyn kartaa saameynta ka hortagga ee qaabka potassium ee necrotizing enteritis.Tijaabadan ayaa sidoo kale lagu ogaaday in qaabka potassium ay kordhisay maadada lactobacilli ee caloosha muruqa ee digaagga broiler 35d, taas oo aan waafaqsanayn Knarreborg et al.(2002) helitaanka vitro in qaabka potassium ay hoos u dhigtay koritaanka lactobacilli ee caloosha doofaarka.

3.Saamaynta potassium-3-dimethylformate ee unugyada pH iyo silsilad gaaban oo ka kooban dufan asiidh dufan ah oo ku jira digaagga broiler ee uu ku dhacay cudurka necrotizing enteritis

Saamaynta bakteeriyada ee acids organic ayaa la aaminsan yahay in ay inta badan ku dhacdo qaybta sare ee habka dheef-shiidka.Natiijooyinka tijaabadani waxay muujiyeen in potassium dicarboxylate ay kordhisay maadada formic acid ee duodenum 15 maalmood iyo jejunum 35 maalmood.Mroz (2005) wuxuu ogaaday inay jiraan arrimo badan oo saameeya ficilka asiidhyada organic, sida quudinta pH, buffering/ashitada, iyo dheellitirka elektrolytka cuntada.Aashitada hoose iyo qiyamka dheellitirka elektrolytka ee cuntada ayaa kor u qaadi kara kala-soocida qaabka potassium-ka ee qaabka formic acid iyo potassium.Sidaa darteed, heerka saxda ah ee acidity iyo electrolyte dheelitirka qiyamka cuntada waxay kor u qaadi kartaa hagaajinta waxqabadka koritaanka broilers by formate potassium iyo saamaynta ka hortagga ah ee necrotizing enteritis.

Gabagabo

Natiijooyinkaqaabka potassiumon model ah necrotizing enteritis ee digaagga broiler muujisay in formate potassium yarayn karaa hoos u dhaca waxqabadka koritaanka digaagga broiler hoos xaaladaha qaarkood by miisaanka jidhka oo kordhay iyo dhimista dhimashada, iyo waxaa loo isticmaali karaa sida daro feed ah si loo xakameeyo caabuqa ee necrotizing enteritis in digaagga broiler.