Ukusetshenziswa kwama-Antibiotics njengabagqugquzeli bokukhula ekukhiqizeni imfuyo kuya ngokuya kubhekwa futhi kugxekwe umphakathi.Ukuthuthukiswa kokungazweli kwamagciwane kuma-antibiotics kanye nokungazweli kwamagciwane abantu nezilwane ahlobene nokwelapha okungaphansi kanye/noma ukusetshenziswa okungafanele kwama-antibiotic yikona okukhathaza kakhulu.

Emazweni e-EU, ukusetshenziswa kwama-antibiotics ukuze kuthuthukiswe ukukhiqizwa kwezilwane kuvinjelwe.E-US, i-American Association's House of Delegates yenza inqubomgomo yagunyaza isinqumo emhlanganweni wayo waminyaka yonke ngo-June inxusa ukuthi ukusetshenziswa “okungekona okokwelapha” kwemithi elwa namagciwane ezilwaneni kuqedwe noma kuqedwe.Isilinganiso sibhekise ngqo kuma-antibiotics anikezwa nabantu.Ifuna uhulumeni ayeke ukusetshenziswa ngokweqile kwama-antibiotics emfuyweni, andise umkhankaso wale nhlangano wokunqanda ukungezwani kwabantu emithini esindisa impilo.Ukusetshenziswa kwama-antibiotic ekukhiqizeni imfuyo kungaphansi kokubuyekezwa kukahulumeni futhi izinyathelo zokulawula ukumelana nemishanguzo zisathuthukiswa.E-Canada, ukusetshenziswa kweCarbadox okwamanje kungaphansi kwe-Health Canada.s ukubuyekeza futhi ubhekane nokuvinjelwa okungenzeka.Ngakho-ke, kuyacaca ukuthi ukusetshenziswa kwama-antibiotics ekukhiqizeni izilwane kuzoncipha futhi kuvinjelwe futhi ezinye izindlela zokugqugquzela ukukhula kwama-antibiotic kufanele ziphenywe futhi zisetshenziswe.

Ngenxa yalokho, ucwaningo luyenziwa njalo ukuze kufundwe ezinye izindlela zokuthatha ama-antibiotics.Ezinye izindlela ezisacwaningwayo zisukela kumakhambi, ama-probiotics, ama-prebiotics nama-asidi aphilayo kuye kwezithasiselo zamakhemikhali namathuluzi okuphatha.Ucwaningo oluningi luye lwabonisa ukuthi i-formic acid iyasebenza ngokumelene namagciwane e-pathogenic.Kodwa-ke, ekusebenzeni, ngenxa yezinkinga zokuphatha, iphunga elinamandla kanye nokugqwala ekusetshenzisweni kokuphakelayo nokudla nokuphuza imishini, ukusetshenziswa kwayo kunqunyelwe.Ukuze kunqotshwe izinkinga, i-potassium diformate (K-diformate) ithole ukunakwa njengenye indlela ye-formic acid ngoba kulula ukuyiphatha kune-asidi emsulwa, kuyilapho iboniswe ngempumelelo ekuthuthukiseni ukusebenza kokukhula kwazo zombili izingulube ezilunyuliwe neziqeda ukukhula. .Ucwaningo olwenziwe abacwaningi e-Agricultural University of Norway (J. Anim. Sci. 2000. 78:1875-1884) lubonise ukuthi ukufakwa kokudla kwe-potassium diformate kumazinga angu-0.6-1.2% kuthuthukisa ukusebenza kokukhula, ikhwalithi yesidumbu kanye nokuphepha kwenyama kumlimi. -izingulube zokuqeda ngaphandle kwemiphumela emibi kukhwalithi yengulube yezinzwa.Kwaboniswa futhi ukuthi akufanii-potassium diformate ukufakwa kwe-Ca/Na-formate akuzange kube nemiphumela nhlobo ekukhuleni nasekhwalithini yesidumbu.

Kulolu cwaningo, kwenziwa ukuhlola okuthathu okuphelele.Esivivinyweni sokuqala, izingulube ezingama-72 (23.1 kg isisindo sokuqala somzimba kanye nesisindo somzimba esingu-104.5 kg) zabelwa ukwelapha okuthathu kokudla (Control, 0.85% Ca/Na-formate and 0.85% potassium-diformate).Imiphumela yabonisa ukuthi ukudla kwe-K-diformate kwenyuse inzuzo yansuku zonke emaphakathi (ADG) kodwa akuzange kube nomthelela esilinganisweni sokuphakelayo kwansuku zonke (ADFI) noma isilinganiso senzuzo/sokuphakelayo (G/F).Okuqukethwe kwe-carcass lean noma okunamafutha akuthintwanga i-potassium -diformate noma i-Ca/Na-formate.

Ekuhlolweni okubili, izingulube ze-10 (i-BW yokuqala: 24.3 kg, i-BW yokugcina: i-85.1 kg) yasetshenziselwa ukutadisha umphumela we-K-diformate ekusebenzeni kanye nekhwalithi yezinzwa zengulube.Zonke izingulube zazikuhlelo lokudla okulinganiselwe futhi zondla ukudla okufanayo ngaphandle kokwengeza u-0.8% we-K-diformate eqenjini lokwelapha.Imiphumela yabonisa ukuthi ukugcwalisa i-K-diformate ekudleni kwandisa i-ADG ne-G/F, kodwa akuzange kube nomthelela kukhwalithi yezinzwa yengulube.

Ekuhlolweni kwesithathu, izingulube ezingama-96 (i-BW yokuqala: 27.1 kg, i-BW yokugcina: 105kg) zabelwa izindlela zokwelapha ezintathu zokudla, eziqukethe u-0, 0.6% kanye no-1.2% K-diformate ngokulandelanayo, ukuze kufundwe umphumela wokwengeza.K-diformateekudleni ekusebenzeni kokukhula, izici zesidumbu kanye, ne-microflora yepheshana lesisu.Imiphumela yabonisa ukuthi ukwengezwa kwe-K-diformate ku-0.6% kanye nezinga le-1.2% kukhuphule ukusebenza kokukhula, ukunciphisa amafutha kanye nephesenti le-carcass lean elithuthukisiwe.Kwatholakala ukuthi ukwengeza i-K-diformate kunciphisa inani lama-coliform emathunjini ezingulube, ngakho-ke, ukuthuthukisa ukuphepha kwengulube.