Kusintha pang'ono kwa ufa wa nsomba ndi soya bean meal (SBM) ngati njira yokhazikika komanso yachuma kwafufuzidwa m'mitundu ingapo yazamalonda yomwe ikufuna kugulitsa nsomba zam'madzi, kuphatikiza nsomba zam'madzi zam'madzi (rainbow trout)Oncorhynchus mykiss).Komabe, soya ndi zinthu zina zochokera ku zomera zimakhala ndi ma saponins ambiri ndi zinthu zina zotsutsana ndi zakudya zomwe zimayambitsa subacute enteritis ya distal intestine zambiri mwa nsombazi.Mkhalidwewu umadziwika ndi kuchuluka kwamatumbo am'mimba, kutupa, ndi zovuta za morphological zomwe zimapangitsa kuchepa kwa chakudya komanso kukula kwapang'onopang'ono.

Mu utawaleza, kuphatikizapo SBM pamwamba pa 20% ya zakudya zasonyezedwa kuti zipangitse soya-enteritis, kuyika malire a thupi pamlingo womwe ungalowe m'malo mwa zakudya zodziwika bwino za m'madzi.Kafukufuku wam'mbuyomu adawunika njira zingapo zothanirana ndi enteritis iyi, kuphatikiza kusintha kwa matumbo a microbiome, kukonza zopangira kuti achotse zinthu zotsutsana ndi zakudya, komanso zowonjezera za antioxidant ndi probiotic.Njira imodzi yomwe sanaizindikire ndikuphatikiza trimethylamine oxide (TMAO) muzakudya zam'madzi.TMAO ndi cytoprotectant yapadziko lonse, yomwe imasonkhanitsidwa m'mitundu yambiri monga mapuloteni ndi membrane stabilizer.Apa, tikuyesa kuthekera kwa TMAO kuti ipititse patsogolo kukhazikika kwa enterocyte ndikupondereza chizindikiro cha HSP70 chotupa potero kulimbana ndi matenda obwera chifukwa cha soya ndikupangitsa kuti chakudya chiwonjezeke, kusunga komanso kukula kwa trout yamadzi amchere.Kupitilira apo, tikuwunika ngati zosungunulira za nsomba zam'madzi, zomwe zili ndi TMAO, zitha kugwiritsidwa ntchito ngati njira yachuma yoperekera chowonjezerachi, ndikupangitsa kuti chigwiritsidwe ntchito pazamalonda.

Mbalame za utawaleza (Troutlodge Inc.) zinali zolemera pafupifupi 40 g ndi n=15 pa thanki imodzi m'matanki opangira katatu.Matanki amadyetsedwa chimodzi mwazakudya zisanu ndi chimodzi zokonzedwa pamaziko a zakudya zomwe zimagayidwa zomwe zimapatsa 40% mapuloteni osungunuka, 15% mafuta osakhazikika, ndikukwaniritsa kuchuluka kwa amino acid.Zakudya zinaphatikizapo kulamulira kwa nsomba 40 (% ya zakudya zowuma), SBM 40, SBM 40 + TMAO 3 g kg^-1, SBM 40 + TMAO 10 g kg^-1, SBM 40 + TMAO 30 g kg^-1, ndi SBM 40 + 10% zosungunulira nsomba.Matanki amadyetsedwa kawiri tsiku lililonse kuti awoneke bwino kwa masabata a 12 ndi kusanthula kwa chimbudzi, pafupi, histological ndi maselo.

Zotsatira za phunziroli zidzakambidwa komanso zofunikira zophatikizapo TMAO kuti athe kugwiritsa ntchito kwambiri mankhwala a soya ku US mumadzi a salmonid.