Betaine, joalo ka choline le methionine, e kenya letsoho ho metabolism ea sehlopha sa methyl sebeteng mme e fana ka sehlopha sa eona sa labile methyl bakeng sa ho kopanya metsoako e mengata ea bohlokoa ea metabolic joalo ka carnitine, creatine le lihormone (bona setšoantšo sa 1)

 

Choline, methionine le betaine kaofela li amana le metabolism ea sehlopha sa methyl.Ka hona, tlatsetso ea betaine e ka fokotsa litlhoko tsa bafani bana ba bang ba sehlopha sa methyl.Ka lebaka leo, e 'ngoe ea litšebeliso tse tsebahalang tsa betaine lijong tsa liphoofolo ke ho nkela (karolo ea) choline chloride le ho eketsa methionine lijong.Ho ipapisitse le litheko tsa 'maraka, liphetoho tsena ka kakaretso li boloka litšenyehelo tsa phepelo, ha li ntse li boloka liphetho tsa ts'ebetso.

Ha betaine e sebelisoa ho nkela li-methyldonors tse ling sebaka, betaine e sebelisoa e le thepa, ho bolelang hore tekanyo ea betaine tlhahisong ea phepelo e ka fetoha mme e ipapisitse le litheko tsa metsoako e amanang joalo ka choline le methionine.Empa, betaine ha e felle feela ka limatlafatsi tse fanang ka methyl mme ho kenyelletsoa ha betaine lijong ho lokela ho nkuoa e le mokhoa oa ho ntlafatsa ts'ebetso.

Betaine joalo ka osmoprotectant

Ntle le ts'ebetso ea eona e le methyldonor, betaine e sebetsa joalo ka osmoregulator.Ha betaine e sa sebelisoe ke sebete ho metabolism ea sehlopha sa methyl, e fumaneha hore lisele li sebelisoe e le organic osmolyte.

Joalo ka osmolyte, betaine e eketsa ho bolokoa ha metsi ka har'a lisele, empa ho feta moo, e tla sireletsa likarolo tsa cellular joalo ka liprotheine, li-enzyme le DNA.Thepa ena ea osmoprotective ea betaine e bohlokoa haholo bakeng sa lisele tse nang le khatello ea maikutlo (osmotic).Ka lebaka la keketseho ea mahloriso a bona a intracellular betaine, lisele tse hatelitsoeng li ka boloka hantle mesebetsi ea bona ea lisele tse kang tlhahiso ea li-enzyme, ho pheta-pheta ha DNA le ho ata ha lisele.Ka lebaka la paballo e ntle ea tšebetso ea cellular, betaine e ka ba le monyetla oa ho ntlafatsa ts'ebetso ea liphoofolo haholo-holo tlas'a maemo a khatello ea maikutlo (khatello ea mocheso, phephetso ea coccidiosis, letsoai la metsi, joalo-joalo).Tlatsetso ea tlatsetso ea betaine phepelong e bonahetse e le molemo maemong a fapaneng le bakeng sa mefuta e fapaneng ea liphoofolo.

Litholoana tse ntle tsa betaine

Mohlomong boemo bo ithutoang ka ho fetesisa mabapi le litlamorao tsa betaine ke khatello ea mocheso.Liphoofolo tse ngata li phela mochesong oa tikoloho o fetang sebaka sa bona sa boiketlo ba mocheso, e leng se lebisang khatellong ea mocheso.

Khatello ea mocheso ke boemo bo tloaelehileng moo ho leng bohlokoa hore liphoofolo li laole tekanyo ea tsona ea metsi.Ka bokhoni ba eona ba ho sebetsa joalo ka osmolyte e sireletsang, betaine e imolla khatello ea mocheso joalo ka ha mohlala o bontšoa ke mocheso o tlase oa rectum le boitšoaro bo fokolang ba likhoho.

Phokotso ea khatello ea mocheso liphoofolong e khothalletsa ho ja lijo tsa tsona le ho thusa ho boloka ts'ebetso.Eseng feela ka likhoho tsa nama, empa hape le ka lihlopha, tse tšehali, tsa mebutlanyana, likhomo tsa lebese le tsa nama ea khomo, litlaleho li bontša liphello tse molemo tsa betaine ho boloka ts'ebetso nakong ea leholimo le chesang hammoho le mongobo o phahameng.Hape, ho ts'ehetsa bophelo bo botle ba mala, betaine e ka thusa.Lisele tsa mala li lula li pepesehetse hyperosmotic ea mala, 'me haeba ho e-na le lets'ollo, bothata ba osmotic bakeng sa lisele tsena bo tla ba holimo.Betaine e bohlokoa bakeng sa tšireletso ea osmotic ea lisele tsa mala.

Ho boloka tekanyo ea metsi le molumo oa sele ka ho bokellana ha intracellular ea betaine ho fella ka ntlafatso ea gut morphology (high villi) le tšilo ea lijo hantle (ka lebaka la ho boloka enzyme e hlokometsoeng hantle le ho eketseha ha bokaholimo bakeng sa ho monya limatlafatsi).Litholoana tse ntle tsa betaine bophelong bo botle ba mala li bonahala haholo-holo liphoofolong tse nang le phephetso: mohlala, likhoho tse nang le coccidiosis le likolobe tse khoesoang.

Betaine e boetse e tsejoa e le phetoho ea setopo.Mesebetsi e mengata ea betaine e bapala karolo ea protheine, matla le metabolism ea mafura liphoofolong.Ka bobeli likhoho le likolobe, lihlahisoa tse phahameng tsa nama ea matsoele le lihlahisoa tsa nama e mafura ka ho latellana, li tlalehoa palo e kholo ea lithuto tsa scientifc.Ho bokella mafura ho boetse ho fella ka ho fokotsa mafura a litopo, ho ntlafatsa boleng ba setopo.

Betaine e le sentlafatso sa ts'ebetso

Litlaleho tsohle tse ntle tse tlalehiloeng tsa betaine li bontša kamoo limatlafatsi tsena li ka bang bohlokoa kateng.Keketso ea betaine lijong ka hona e lokela ho nkoa, eseng feela e le thepa ea ho nka sebaka sa li-methyldonors tse ling le litšenyehelo tsa ho boloka phepelo, empa hape e le tlatsetso e sebetsang ho ts'ehetsa bophelo bo botle le ts'ebetso ea liphoofolo.

Phapang lipakeng tsa lits'ebetso tsena tse peli ke litekanyetso.Joalo ka methyldonor, betaine hangata e tla sebelisoa lijong ka litekanyetso tsa 500ppm kapa ho feta.Ho ntlafatsa ts'ebetso hangata ho sebelisoa litekanyetso tsa 1000-to-2000ppm betaine.Litekanyetso tsena tse phahameng li etsa hore betaine e se ke ea senyeha, e potolohang 'meleng oa liphoofolo, e fumanehang bakeng sa ho amoheloa ke lisele ho li sireletsa khahlanong le khatello ea maikutlo (osmotic) le ho tšehetsa bophelo le ts'ebetso ea liphoofolo.

Qetello

Betaine e na le ts'ebeliso e fapaneng bakeng sa mefuta e fapaneng ea liphoofolo.Lijong tsa liphoofolo betaine e ka sebelisoa e le thepa ea ho boloka litšenyehelo tsa lijo, empa e ka boela ea kenyelletsoa lijong ho ntlafatsa bophelo ba liphoofolo le ho matlafatsa ts'ebetso.Haholo-holo matsatsing ana, moo re lekang ho fokotsa tšebeliso ea lithibela-mafu, ho tšehetsa bophelo ba liphoofolo ke habohlokoa haholo.Betaine ka sebele e lokeloa ke sebaka lethathamong la metsoako e meng ea bioactive ho tšehetsa bophelo ba liphoofolo.