ʻO Tributyrin supplementation i ka iʻa a me ka meaʻai crustacean

Ua hoʻohana ʻia nā ʻakika momona pōkole, me ka butyrate a me kāna mau ʻano i loaʻa, i mea hoʻohui meaʻai e hoʻohuli a hoʻomaikaʻi paha i nā hopena maikaʻi ʻole o nā mea kanu i loaʻa i nā mea kanu i nā meaʻai iʻa, a loaʻa i ka lehulehu o nā hopena physiological a me ke olakino hoʻomaikaʻi maikaʻi. nā mammals a me nā holoholona.Ua helu ʻia ʻo Tributyrin, kahi ʻakika butyric i hoʻohui ʻia i nā meaʻai o nā holoholona mahiʻai, me nā hopena hoʻohiki i kekahi mau ʻano.I nā iʻa a me nā crustaceans, ʻoi aku ka hou o ka hoʻokomo ʻana i ka tributyrin i ka meaʻai a ʻaʻole i aʻo ʻia akā ʻike ʻia nā hopena he mea maikaʻi loa ia no nā holoholona wai.He mea koʻikoʻi kēia no nā ʻano mea ʻai ʻai, pono e hoʻomaikaʻi maikaʻi ʻia nā meaʻai no ka hōʻemi ʻana i ka ʻai iʻa i mea e hoʻoikaika ai i ka hoʻomau kaiapuni a me ka hoʻokele waiwai o ka ʻāpana.Hōʻike ka hana i kēia manawa i ka tributyrin a hōʻike i nā hopena nui o kāna hoʻohana ʻana ma ke ʻano he kumu ʻai o ka waikawa butyric i nā meaʻai no nā ʻano wai.Hāʻawi ʻia ka manaʻo nui i nā ʻano iʻa aʻa a pehea e hiki ai i ka tributyrin, ma ke ʻano he meaʻai meaʻai, ke kōkua i ka hoʻomaikaʻi ʻana i nā aquafeeds.

Hua'ōlelo

aquafeed, butyrate, butyric acid, nā ʻakika momona pōkole, triglyceride

1. Butyric acid a me ke ola kinoHe pōkole nā ʻōpū hoʻoheheʻe ʻana o nā holoholona wai, pōkole ka manawa mālama ʻai i loko o ka ʻōpū, a ʻo ka hapa nui o lākou ʻaʻohe ʻōpū.Hāpai ka ʻōpū i nā hana ʻelua o ka digestion a me ka absorption.He mea koʻikoʻi ka ʻōpū no nā holoholona aquatic, no laila ʻoi aku ka nui o nā koi no nā mea hānai.He kiʻekiʻe ko nā holoholona wai i ka protein.Hoʻohana pinepine ʻia ka nui o nā mea kanu protein i loaʻa nā mea anti-nutritional, e like me ka pulupulu rapeseed meal, i loko o ka meaʻai iʻa e pani i ka ʻai iʻa, kahi mea maʻalahi i ka hōʻino ʻana o ka protein a i ʻole ka momona momona, e hōʻino ai i ka ʻōpū i nā holoholona wai.Poor quality protein kumu hiki ke hoemi nui i ke kiʻekiʻe o ka intestinal mucosa, blur a hiki i hookahe epithelial mau keena, a hoonui vacuoles, ka mea, aole wale i kaupalena 'ana i ka digestion a me ka absorption o ka meaʻai meaʻai, akā, e pili ana i ka ulu o aquatic holoholona.No laila, he mea koʻikoʻi loa ka pale ʻana i ka ʻōpū o nā holoholona aquatic.ʻO ka ʻakika Butyric kahi ʻakika momona kaulahao pōkole i loaʻa mai ka fermentation o nā hua bacteria maikaʻi o ka ʻōpū e like me ka lactic acid bacteria a me ka bifidobacteria.Hiki ke hoʻopili pololei ʻia ka waikawa Butyric e nā ʻāpana epithelial intestinal, ʻo ia kekahi o nā kumu ikehu nui o nā ʻāpana epithelial intestinal.Hiki iā ia ke hoʻoikaika i ka hoʻonui a me ka hoʻomāhuahuaʻana o nā pūnaewele'ōpū, mālama i ka pono o nā pūnaewele epithelial intestinal, a hoʻonui i ka pale mucosal intestinal;Ma hope o ke komo ʻana o ka waikawa butyric i nā pūnaewele bacteria, ua decomposed i loko o nā ion butyrate a me nā ion hydrogen.Hiki ke pale i ka ulu ʻana o nā hua bacteria ʻino e like me Escherichia coli a me Salmonella, ʻoiai ʻo nā hua bacteria maikaʻi e like me ka lactic acid bacteria e hoʻonui nui ʻia ma muli o ko lākou pale ʻana i ka waikawa, no laila e hoʻomaikaʻi ana i ke ʻano o ka digestive tract flora;Hiki i ka ʻakika Butyric ke kāohi i ka hana ʻana a me ka hōʻike ʻana i nā mea proinflammatory i loko o ka mucosa intestinal, kaohi ʻana i ka hopena inflammatory, a hoʻohaʻahaʻa i ka ʻeha o ka ʻōpū;He mau hana koʻikoʻi ko ka Butyric acid i ke olakino ʻōpū.

2. Glyceryl butyrate

He ʻala maikaʻi ʻole ka Butyric acid a maʻalahi hoʻi e hoʻololi, a he paʻakikī ke hiki i ka hope o ka ʻōpū e hana i kahi kuleana ma hope o ka ʻai ʻia e nā holoholona, no laila ʻaʻole hiki ke hoʻohana pololei ʻia i ka hana.ʻO Glyceryl butyrate ka huahana momona o ka waikawa butyric a me ka glycerin.Hoʻopaʻa ʻia ka ʻakika Butyric a me ka glycerin e nā paʻa covalent.Paʻa lākou mai ka pH1-7 a i ka 230 ℃.Ma hope o ka ʻai ʻia ʻana e nā holoholona, ʻaʻole decompose ka glyceryl butyrate i loko o ka ʻōpū, akā decompose i loko o ka waikawa butyric a me ka glycerin i loko o ka ʻōpū ma lalo o ka hana a ka pancreatic lipase, e hoʻokuʻu mālie i ka waikawa butyric.ʻO Glyceryl butyrate, ma ke ʻano he meaʻai meaʻai, maʻalahi e hoʻohana, palekana, ʻaʻohe mea ʻawaʻawa, a he ʻono kūikawā.ʻAʻole wale ia e hoʻonā i ka pilikia he paʻakikī ka paʻakikī o ka butyric acid e hoʻohui ʻia me he wai lā a ʻala maikaʻi ʻole, akā hoʻomaikaʻi pū i ka pilikia e paʻakikī ai ka waikawa butyric e hiki i ka ʻāpana ʻōpū ke hoʻohana pololei ʻia.Manaʻo ʻia ʻo ia kekahi o nā derivatives butyric acid maikaʻi loa a me nā huahana anti histamine.

2.1 Glyceryl Tributyrate a me Glyceryl Monobutyrate

TributyrinAia i loko o 3 mau mole o ka butyric acid a me 1 mole o ka glycerol.Hoʻokuʻu mālie ʻo Tributyrin i ka waikawa butyric i loko o ka ʻōpū ma o ka pancreatic lipase, kahi i hoʻokuʻu ʻia ma ke alo o ka ʻōpū, a hiki i kahi ʻāpana ke hiki i ke kua o ka ʻōpū e pāʻani i kahi kuleana;Hoʻokumu ʻia ka monobutyric acid glyceride e hoʻokahi mole o ka waikawa butyric e paʻa ana i ka pae mua o ka glycerol (Sn-1 site), nona nā waiwai hydrophilic a me lipophilic.Hiki iā ia ke hōʻea i ka hope o ka ʻōpū me ka wai hoʻoheheʻe.Hoʻokuʻu ʻia kekahi ʻakika butyric e ka pancreatic lipase, a ʻo kekahi e hoʻopili pololei ʻia e nā cell epithelial intestinal.Ua decomposed i butyric acid a me glycerol i loko o ka intestinal mucosal cell, paipai i ka ulu o intestinal villi.He molecular polarity a me ka nonpolarity ʻo Glyceryl butyrate, hiki iā ia ke komo pono i ka membrane hydrophilic a lipophilic cell wall o ka bacteria pathogenic nui, hoʻouka i nā cell bacteria, luku i ke ʻano o ka cell, a pepehi i nā maʻi ʻino.He hopena antibacterial ikaika ko Monobutyric acid glyceride i ka hua bacteria gram-positive a me gram-negative bacteria, a ʻoi aku ka maikaʻi o ka hopena antibacterial.

2.2 Ka hoʻohana ʻana i ka glyceryl butyrate i nā huahana wai

ʻO Glyceryl butyrate, ma ke ʻano he derivative o ka butyric acid, hiki ke hoʻokuʻu maikaʻi i ka waikawa butyric ma lalo o ka hana o ka lipase pancreatic intestinal, a ʻaʻohe ʻala, kūpaʻa, palekana a me ke koena manuahi.ʻO ia kekahi o nā mea koho maikaʻi loa i nā lāʻau antibiotic a hoʻohana nui ʻia i ka iʻa.Zhai Qiuling et al.Ua hōʻike ʻia i ka wā i hoʻohui ʻia ai ka 100-150 mg / kg tributylglycerol ester i ka meaʻai, hiki ke loaʻa ka nui o ke kaumaha, ka nui o ka ulu ʻana, nā hana o nā enzyme digestive like ʻole a me ke kiʻekiʻe o ka villi intestinal ma mua a ma hope o ka hoʻohui ʻana o 100 mg / kg tributylglycerol ester hiki ke e hoonui loa ia;Uaʻikeʻo Tang Qifeng a me nā mea noiʻi'ē aʻe i ka hoʻonuiʻana i ka 1.5g / kg tributylglycerol ester i ka hānai hiki ke hoʻonui i ka hana ulu o Penaeus vannamei, a hoʻemi nui i ka helu o nā vibrio pathogenic i loko o ka'ōpū;ʻO Jiang Yingying et al.ʻike ʻia ʻo ka hoʻohui ʻana i ka 1g/kg o ka tributyl glyceride i ka hānai hiki ke hoʻonui nui i ka nui o ke kaumaha o Allogynogenetic crucian carp, hoʻemi i ka coefficient hānai, a hoʻonui i ka hana o ka superoxide dismutase (SOD) i ka hepatopancreas;Ua hōʻike kekahi mau haʻawina i ka hoʻohui ʻana o 1000 mg / kgtributyl glyceridei ka meaʻai hiki ke hoʻonui nui i ka hana o ka intestinal superoxide dismutase (SOD) o Jian carp.

Ka manawa hoʻouna: Jan-05-2023