Mafuta afupiafupi, kuphatikizapo butyrate ndi mawonekedwe ake, akhala akugwiritsidwa ntchito ngati zowonjezera zakudya kuti athetse kapena kuchepetsa zotsatira zoipa zomwe zimachokera ku zomera muzakudya zam'madzi, ndikukhala ndi zambiri zowonetsetsa bwino za thupi ndi thanzi labwino mu zoyamwitsa ndi ziweto.Tributyrin, chochokera ku butyric acid, adawunikidwa ngati chowonjezera pazakudya za nyama zowetedwa, zomwe zimakhala ndi zotsatira zabwino m'mitundu ingapo.Mu nsomba ndi crustaceans, zakudya kuphatikizapo tributyrin ndi posachedwapa ndipo sanaphunzire kwenikweni koma zotsatira zimasonyeza kuti zingakhale zopindulitsa kwambiri kwa nyama zam'madzi.Izi ndizofunikira makamaka kwa nyama zodya nyama, zomwe zakudya zake ziyenera kukonzedwa kuti zichepetse ufa wa nsomba pofuna kupititsa patsogolo chilengedwe ndi chuma cha gawoli.Ntchito yomwe ilipo pano imadziwika ndi tributyrin ndipo ikuwonetsa zotsatira zazikulu za kugwiritsidwa ntchito kwake ngati gwero lazakudya la butyric acid muzakudya zamitundu yam'madzi.Cholinga chachikulu chimaperekedwa ku mitundu ya zamoyo zam'madzi komanso momwe tributyrin, monga chowonjezera cha chakudya, ingathandizire kukulitsa bwino zamadzi am'madzi am'madzi.
2. Glyceryl butyrate
Asidi wa Butyric ali ndi fungo losasangalatsa ndipo ndi losavuta kusinthasintha, ndipo n'zovuta kufika kumapeto kwa matumbo kuti agwire ntchito atadyedwa ndi nyama, choncho sangathe kugwiritsidwa ntchito mwachindunji popanga.Glyceryl butyrate ndi mafuta opangidwa ndi butyric acid ndi glycerin.Butyric acid ndi glycerin amamangidwa ndi ma covalent bonds.Iwo ndi okhazikika kuchokera pH1-7 mpaka 230 ℃.Pambuyo pa kudyedwa ndi nyama, glyceryl butyrate sichiwola m'mimba, koma imawola kukhala butyric acid ndi glycerin m'matumbo pogwira ntchito ya pancreatic lipase, ndikutulutsa pang'onopang'ono butyric acid.Glyceryl butyrate, monga chowonjezera cha chakudya, ndiyosavuta kugwiritsa ntchito, yotetezeka, yopanda poizoni, ndipo imakhala ndi kukoma kwapadera.Sikuti amangothetsa vutoli kuti asidi butyric ndi zovuta kuwonjezera ngati madzi ndi fungo loipa, komanso bwino vuto kuti butyric asidi n'zovuta kufika matumbo thirakiti ntchito mwachindunji.Imawerengedwa kuti ndi imodzi mwazinthu zabwino kwambiri zochokera ku butyric acid ndi anti histamine.
2.1 Glyceryl Tributyrate ndi Glyceryl Monobutyrate
Tributyrinimakhala ndi mamolekyu atatu a butyric acid ndi molekyulu imodzi ya glycerol.Tributyrin imatulutsa pang'onopang'ono asidi wa butyric m'matumbo kudzera mu pancreatic lipase, gawo lomwe limatulutsidwa kutsogolo kwa matumbo, ndipo gawo lomwe limatha kufikira kumbuyo kwa matumbo kuti ligwire ntchito;Monobutyric acid glyceride imapangidwa ndi molekyu imodzi ya butyric acid yomangiriza ku malo oyamba a glycerol (Sn-1 site), yomwe ili ndi hydrophilic ndi lipophilic properties.Ikhoza kufika kumapeto kwa matumbo ndi madzi am'mimba.Asidi ena a butyric amatulutsidwa ndi pancreatic lipase, ndipo ena amatengedwa mwachindunji ndi maselo am'mimba a epithelial.Imasungunuka kukhala butyric acid ndi glycerol m'maselo amatumbo am'mimba, zomwe zimathandizira kukula kwamatumbo am'mimba.Glyceryl butyrate ili ndi mamolekyulu polarity ndi nonpolarity, omwe amatha kulowa bwino mu hydrophilic kapena lipophilic cell khoma nembanemba ya mabakiteriya akuluakulu oyambitsa matenda, kulowa m'maselo a bakiteriya, kuwononga ma cell, ndikupha mabakiteriya oyipa.Monobutyric acid glyceride imakhala ndi antibacterial wamphamvu pa mabakiteriya omwe ali ndi gramu komanso mabakiteriya opanda gramu, ndipo imakhala ndi antibacterial effect.
2.2 Kugwiritsa ntchito glyceryl butyrate muzinthu zam'madzi
Glyceryl butyrate, monga chochokera ku butyric acid, imatha kumasula butyric acid mogwira ntchito ya m'matumbo a pancreatic lipase, ndipo imakhala yopanda fungo, yokhazikika, yotetezeka komanso yopanda zotsalira.Ndi imodzi mwa njira zabwino zopangira maantibayotiki ndipo imagwiritsidwa ntchito kwambiri pazaulimi.Zhai Qiuling et al.anasonyeza kuti pamene 100-150 mg/kg tributylglycerol ester anawonjezedwa kwa chakudya, mlingo wolemera, mlingo wa kukula, zochita za michere zosiyanasiyana m'mimba ndi kutalika kwa matumbo villi pamaso ndi pambuyo Kuwonjezera 100 mg/kg tributylglycerol ester akhoza. kukula kwambiri;Tang Qifeng ndi ofufuza ena adapeza kuti kuwonjezera 1.5g / kg tributylglycerol ester ku chakudya kungathandize kwambiri kukula kwa Penaeus vannamei, komanso kuchepetsa kwambiri chiwerengero cha tizilombo toyambitsa matenda m'matumbo;Jiang Yingying et al.anapeza kuti kuwonjezera 1g/kg ya tributyl glyceride ku chakudya kungathe kuonjezera kulemera kwa carp Allogynogenetic crucian carp, kuchepetsa chakudya chochepa, ndikuwonjezera ntchito ya superoxide dismutase (SOD) mu hepatopancreas;Kafukufuku wina adawonetsa kuti kuwonjezera kwa 1000 mg / kgtributyl glyceridepazakudya zitha kuwonjezera kwambiri matumbo a superoxide dismutase (SOD) a Jian carp.
Nthawi yotumiza: Jan-05-2023