Mgbakwunye Tributyrin na azụ na nri crustacean

Ejirila acid fatty dị mkpụmkpụ, gụnyere butyrate na ụdị ya ewepụtara, dị ka mgbakwunye nri iji tụgharịa ma ọ bụ meziwanye mmetụta ọjọọ nke ihe ọkụkụ sitere na nri aquaculture, ma nwee ọtụtụ ihe ngosipụta nke ọma gbasara ahụike na nkwalite ahụike. mammals na anụ ụlọ.A tụlere Tributyrin, butyric acid derivate, dị ka mgbakwunye na nri anụmanụ ndị a na-akọ ugbo, na-arụpụta ihe dị mma n'ụdị dị iche iche.N'ime azụ na crustaceans, ntinye nri nke tributyrin bụ ihe na-adịbeghị anya ma a mụọbeghị ya mana nsonaazụ na-egosi na ọ nwere ike ịba uru nke ukwuu maka anụ mmiri.Nke a dị mkpa karịsịa maka ụdị anụ anụ, ndị ọ dị mkpa ka emeziwanye ihe oriri ha maka mbelata ọdịnaya nri azụ iji kwalite nkwado gburugburu ebe obibi na akụ na ụba nke ngalaba ahụ.Ọrụ dị ugbu a na-akọwapụta tributyrin ma gosipụta isi ihe sitere na ojiji ya dị ka isi iyi nke butyric acid na nri maka ụdị mmiri.Isi ihe a na-elekwasị anya bụ ụdị aquaculture na otú tributyrin, dị ka ihe mgbakwunye nri, nwere ike isi nye aka n'ịkwalite ihe ọkụkụ ndị dabeere na aquafeed.

Okwu

aquafeed, butyrate, butyric acid, obere yinye fatty acids, triglyceride

1. Butyric acid na ahụ ike nke eriri afọAnụmanụ ndị dị n'ime mmiri nwere akụkụ ahụ mgbari nri dị mkpụmkpụ, oge njide nri dị mkpụmkpụ n'ime eriri afọ, ọtụtụ n'ime ha enweghị afọ.eriri afọ na-ebu ọrụ abụọ nke mgbaze na absorption.eriri afọ dị ezigbo mkpa maka anụmanụ mmiri, ya mere ọ nwere ihe dị elu chọrọ maka ihe oriri.Anụmanụ ndị dị n'ime mmiri nwere nnukwu agụụ maka protein.A na-ejikarị ọnụ ọgụgụ dị ukwuu nke protein protein ihe ọkụkụ nwere ihe mgbochi nri, dị ka nri owu rapeseed, na nri mmiri iji dochie nri azụ, nke na-enwekarị mmebi protein ma ọ bụ oxidation abụba, na-eme ka eriri afọ mebie anụmanụ mmiri.Ogbenye àgwà protein isi iyi nwere ike budata ibelata elu nke eriri afọ mucosa, blur ma ọ bụ ọbụna wụsara epithelial sel, na-abawanye vacuoles, nke ọ bụghị nanị na-amachi mgbaze na absorption nke fiidi nri, ma na-emetụta uto nke aquatic anụmanụ.Ya mere, ọ dị ngwa ngwa iji chebe akụkụ eriri afọ nke anụmanụ mmiri.Butyric acid bụ obere yinye fatty acid sitere na gbaa ụka nke nje bacteria bara uru dị ka nje lactic acid na bifidobacteria.Butyric acid nwere ike ịmịnye ya ozugbo site na mkpụrụ ndụ epithelial intestinal, nke bụ otu n'ime isi mmalite ike nke mkpụrụ ndụ epithelial intestinal.Ọ nwere ike ịkwalite mmụba na ntozu nke mkpụrụ ndụ eriri afọ, na-ejigide iguzosi ike n'ezi ihe nke mkpụrụ ndụ epithelial intestinal, ma kwalite ihe mgbochi mucosal eriri afọ;Mgbe butyric acid batara n'ime mkpụrụ ndụ nje, ọ na-aghọ ion butyrate na ion hydrogen.Ọnụnọ dị elu nke ion hydrogen nwere ike igbochi uto nke nje bacteria na-emerụ ahụ dị ka Escherichia coli na Salmonella, ebe nje bacteria bara uru dị ka nje bacteria lactic acid na-amụba n'ọtụtụ buru ibu n'ihi nguzogide acid ha, si otú a na-eme ka nhazi nke ahịhịa nri digestive;Butyric acid nwere ike igbochi mmepụta na nkwupụta nke proinflammatory ihe na eriri afọ mucosa, na-egbochi mmeghachi omume mkpali, ma na-ebelata mbufụt nke eriri afọ;Butyric acid nwere ọrụ physiological dị mkpa na ahụike eriri afọ.

2. Glyceryl butyrate

Butyric acid nwere isi na-adịghị mma ma dị mfe ịgbagha, ọ na-esikwa ike iru azụ azụ nke eriri afọ iji rụọ ọrụ mgbe anụmanụ riri ya, yabụ enweghị ike iji ya mee ihe ozugbo na mmepụta ya.Glyceryl butyrate bụ abụba butyric acid na glycerin.A na-ejikọta Butyric acid na glycerin site na njikọ covalent.Ha kwụsiri ike site na pH1-7 ruo 230 ℃.Mgbe anụmanụ richara ya, glyceryl butyrate anaghị ere ere n'ime afọ, kama ọ na-aghọ butyric acid na glycerin n'ime eriri afọ n'okpuru ọrụ pancreatic lipase, na-eji nwayọọ nwayọọ na-ahapụ butyric acid.Glyceryl butyrate, dị ka ihe mgbakwunye nri, dị mma iji, dị mma, anaghị egbu egbu, ma nwee ụtọ pụrụ iche.Ọ bụghị naanị na-edozi nsogbu ahụ na butyric acid siri ike ịgbakwunye dị ka mmiri mmiri na-esi ísì ọjọọ, kamakwa ọ na-eme ka nsogbu ahụ dịkwuo mma na butyric acid na-esi ike iru eriri afọ mgbe ejiri ya ozugbo.A na-ewere ya dị ka otu n'ime ihe ndị na-emepụta butyric acid kacha mma na ngwaahịa antihistamine.

2.1 Glyceryl Tributyrate na Glyceryl Monobutyrate

Tributyrinnwere molekul 3 nke butyric acid na 1 molecule nke glycerol.Tributyrin ji nwayọọ nwayọọ na-ewepụta acid butyric na eriri afọ site na pancreatic lipase, nke a na-ewepụta akụkụ ya n'ihu eriri afọ, na akụkụ nke nwere ike iru azụ nke eriri afọ iji rụọ ọrụ;A na-emepụta Monobutyric acid glyceride site na otu molekul nke butyric acid na-ejikọta na saịtị mbụ nke glycerol (Sn-1 saịtị), nke nwere hydrophilic na lipophilic Njirimara.Ọ nwere ike iru n'azụ eriri afọ na ihe ọṅụṅụ digestive.A na-ewepụta ụfọdụ butyric acid site na pancreatic lipase, ụfọdụ na-abanyekwa ozugbo site na mkpụrụ ndụ epithelial eriri afọ.A na-ekewa ya na butyric acid na glycerol na sel mucosal intestinal, na-akwalite uto nke villi intestinal.Glyceryl butyrate nwere polarity molecular na nonpolarity, nke nwere ike banye n'ụzọ dị irè banye na hydrophilic ma ọ bụ lipophilic cell membrane nke nje bacteria na-akpata isi, na-awakpo mkpụrụ ndụ nje, na-ebibi usoro cell, ma gbuo nje bacteria na-emerụ ahụ.Monobutyric acid glyceride nwere mmetụta antibacterial siri ike na nje bacteria gram-positive na gram-negative bacteria, ma nwee mmetụta antibacterial ka mma.

2.2 Ngwa nke glyceryl butyrate na ngwaahịa mmiri

Glyceryl butyrate, dị ka ihe sitere na butyric acid, nwere ike hapụ butyric acid nke ọma n'okpuru ọrụ nke lipase intestinal pancreatic lipase, ọ nweghị isi, kwụsiri ike, enweghị nchekwa na nke fọdụrụ.Ọ bụ otu n'ime ụzọ kachasị mma maka ọgwụ nje na nke a na-ejikarị eme ihe na aquaculture.Zhai Qiuling et al.gosiri na mgbe 100-150 mg / kg tributylglycerol ester na-agbakwunyere na ndepụta, uru uru ọnụego, kpọmkwem uto ọnụego, omume nke dị iche iche digestive enzymes na elu nke intestinal villi tupu na mgbe mgbakwunye nke 100 mg / kg tributylglycerol ester nwere ike. a ga-ebuwanye ibu;Tang Qifeng na ndị ọzọ na-eme nchọpụta chọpụtara na-agbakwụnye 1.5g/kg tributylglycerol ester na ndepụta nwere ike budata mma uto arụmọrụ nke Penaeus vannamei, na budata ibelata ọnụ ọgụgụ nke pathogenic vibrio na eriri afọ;Jiang Yingying et al.chọpụtara na ịgbakwụnye 1g / kg nke tributyl glyceride na nri nwere ike ịbawanye ụbara ibu arọ nke Allogynogenetic crucian carp, belata ọnụ ọgụgụ nri, na ịbawanye ọrụ nke superoxide dismutase (SOD) na hepatopancreas;Ụfọdụ ọmụmụ gosiri na mgbakwunye 1000 mg / kgtributyl glyceridena nri nwere ike budata mụbaa intestinal superoxide dismutase (SOD) ọrụ nke Jian azu kaapu.

Oge nzipu: Jan-05-2023