Tributyrin supplementation muhove uye crustacean chikafu

Short-chain fatty acids, kusanganisira butyrate uye mafomu ayo akatorwa, akashandiswa sezvekudya zvekuwedzera kudzoreredza kana kunatsiridza zvingangove zvakashata zvinokonzeresa zvinokonzerwa nezvirimwa zvinotorwa mukudya kwemvura, uye kuve nezvakawanda zvakaratidzwa zvakanaka zvemuviri uye hutano zvinosimudzira mhedzisiro. zvinoyamwisa nezvipfuwo.Tributyrin, iyo butyric acid inotorwa, yakaongororwa sekuwedzera mukudya kwemhuka dzakarimwa, nemhedzisiro inovimbisa mumarudzi akati wandei.Muhove nemacrustaceans, kudya kunosanganisirwa kwe tributyrin kuchangopfuura uye hakuna kudzidzwa zvishoma asi mhedzisiro inoratidza kuti inogona kubatsira zvakanyanya kumhuka dzemumvura.Izvi zvakanyanya kukosha kumhuka dzinodya nyama, dzine kudya kunoda kugadziridzwa kusvika pakudzikiswa kwehupfu hwehove kusimudzira nharaunda nehupfumi hwechikamu.Iri basa razvino rinoratidzira tributyrin uye rinopa mhedzisiro huru yekushandiswa kwayo sechikafu sosi yebutyric asidhi mune zvekudya zvemarudzi emvura.Chinonyanya kutariswa chinopihwa kune mhuka dzemumvura uye kuti tributyrin, sechikafu chekuwedzera, inogona kubatsira mukugadzirisa chirimwa-based aquafeeds.

Keywords

aquafeed, butyrate, butyric acid, short-chain fatty acids, triglyceride

1. Butyric acid uye hutano hwematumboMhuka dzemumvura dzine nhengo pfupi dzekugaya, nguva pfupi yekuchengetedza chikafu mumatumbo, uye mazhinji acho haana dumbu.Ura hunoita mabasa maviri ekugayiwa nekunyudza.Ura hwakakosha zvikuru kumhuka dzemumvura, saka hune zvinodiwa zvepamusoro pezvekudya.Mhuka dzemumvura dzine chido chikuru cheprotein.Huwandu hukuru hwezvirimwa zveprotein zvinhu zvine anti nutritional factor, senge donje rapeseed meal, inowanzoshandiswa mukudya kwemvura kutsiva hove hove, iyo inokonzeresa kuparara kweprotein kana mafuta oxidation, zvichikonzera kukuvara kwematumbo kumhuka dzemvura.Yakashata yemhando yeprotein sosi inogona kuderedza zvakanyanya kureba kwemukati mucosa, blur kana kutodurura epithelial masero, uye kuwedzera vacuoles, izvo zvisingangodzikisi kugaya uye kutora kwekudya, asiwo zvinokanganisa kukura kwemhuka dzemumvura.Naizvozvo, zvinokurumidza kukurumidza kudzivirira mudumbu wemhuka dzemumvura.Butyric asidhi ipfupi ketani yemafuta asidhi inotorwa kubva mukuvirisa kwemabhakitiriya anobatsira emudumbu akadai selactic acid bacteria uye bifidobacteria.Butyric acid inogona kubatwa zvakananga nemukati epithelial masero, inova imwe yemasimba makuru emukati epithelial masero.Inogona kukurudzira kupararira nekukura kwemasero emimba, kuchengetedza kutendeseka kwemasero epithelial emukati, uye kuwedzera intestinal mucosal barrier;Mushure mekunge butyric acid inopinda mumasero ebhakitiriya, inosvibiswa kuita butyrate ions uye hydrogen ions.High concentration yehydrogen ions inogona kudzivisa kukura kwebhakitiriya inokuvadza yakadai seEscherichia coli uye Salmonella, nepo mabhakitiriya anobatsira akadai selactic acid mabhakitiriya anopararira muhuwandu huzhinji nekuda kwekusagadzikana kweasidhi, nokudaro kugadzirisa chimiro chekudya kwemafuta;Butyric acid inogona kurambidza kugadzirwa uye kutaura kweproinflammatory zvinhu mu intestinal mucosa, inhibit inflammatory reaction, uye kuderedza kuputika kwemukati;Butyric acid ine zvakakosha zvemuviri mabasa muhutano hwematumbo.

2. Glyceryl butyrate

Butyric acid ine kunhuhwirira kusingafadzi uye iri nyore kuvhuvhuta, uye zvakaoma kusvika kumucheto kumashure kweura kuita basa mushure mekudyiwa nemhuka, saka haigone kushandiswa zvakananga mukugadzira.Glyceryl butyrate ndiyo ine mafuta chigadzirwa che butyric acid uye glycerin.Butyric acid uye glycerin zvakasungwa ne covalent bonds.Dzakagadzikana kubva pH1-7 kusvika 230 ℃.Mushure mekudyiwa nemhuka, glyceryl butyrate haiparare mudumbu, asi inoparara kuita butyric acid uye glycerin mumatumbo pasi pekuita kwepancreatic lipase, zvishoma nezvishoma kuburitsa butyric acid.Glyceryl butyrate, sekuwedzera kwekudya, iri nyore kushandisa, yakachengeteka, isina chepfu, uye ine yakasarudzika flavour.Haisi kungogadzirisa dambudziko rekuti butyric acid yakaoma kuwedzera semvura uye inonhuwa zvakaipa, asiwo inovandudza dambudziko rekuti butyric acid yakaoma kusvika mudumbu kana yakashandiswa zvakananga.Inoonekwa seimwe yeakanakisa butyric acid inotorwa uye anti histamine zvigadzirwa.

2.1 Glyceryl Tributyrate uye Glyceryl Monobutyrate

Tributyrinine 3 mamorekuru e butyric acid uye 1 molecule ye glycerol.Tributyrin zvishoma nezvishoma inoburitsa butyric acid muura kuburikidza nepancreatic lipase, chikamu chayo chinoburitswa pamberi peura, uye chikamu chinogona kusvika kumashure kwemukati kuita basa;Monobutyric acid glyceride inoumbwa neimwe molecule ye butyric acid inosunga kune yekutanga saiti ye glycerol (Sn-1 saiti), ine hydrophilic uye lipophilic zvinhu.Inogona kusvika kumucheto kumashure kwemukati nemuto wekudya.Imwe butyric acid inoburitswa nepancreatic lipase, uye imwe inotorwa zvakananga nemukati epithelial masero.Iyo yakasvibiswa kuita butyric acid uye glycerol mumatumbo emucosal masero, achikurudzira kukura kweintestinal villi.Glyceryl butyrate ine molecular polarity uye nonpolarity, iyo inogona kunyatsopinda mukati me hydrophilic kana lipophilic cell wall membrane yeiyo main pathogenic bacteria, inopinda mumasero ebhakitiriya, kuparadza chimiro chesero, uye kuuraya mabhakitiriya anokuvadza.Monobutyric acid glyceride ine yakasimba antibacterial effect pa gram-positive bacteria uye gram-negative bacteria, uye ine antibacterial effect iri nani.

2.2 Kushandiswa kweglyceryl butyrate muzvigadzirwa zvemumvura

Glyceryl butyrate, seyakatorwa kubva ku butyric acid, inogona kunyatso kuburitsa butyric acid pasi pechiito chemukati pancreatic lipase, uye haina kunhuhwirira, yakagadzikana, yakachengeteka uye yakasununguka yakasununguka.Ndiyo imwe yedzakanakisa dzimwe nzira dzemishonga inorwisa mabhakitiriya uye inoshandiswa zvakanyanya mu aquaculture.Zhai Qiuling et al.yakaratidza kuti apo 100-150 mg / kg tributylglycerol ester yakawedzerwa kune zvokudya, kuwedzera kwehuwandu hwehuwandu, huwandu hwekukura, zviitiko zvema enzymes akasiyana-siyana ekudya uye kureba kwemukati villi pamberi uye shure kwekuwedzera kwe100 mg / kg tributylglycerol ester inogona. kuwedzera zvakanyanya;Tang Qifeng nevamwe vatsvakurudzi vakawana kuti kuwedzera 1.5g / kg tributylglycerol ester kune zvokudya zvinogona kuvandudza zvakanyanya kukura kwePenaeus vannamei, uye kuderedza zvakanyanya nhamba yepathogenic vibrio mumatumbo;Jiang Yingying et al.akawana kuti kuwedzera 1g / kg ye tributyl glyceride kune zvokudya zvinogona kuwedzera zvakanyanya kuwanda kwehuwandu hweAllogynogenetic crucian carp, kuderedza chikafu chekudya, uye kuwedzera basa re superoxide dismutase (SOD) mu hepatopancreas;Zvimwe zvidzidzo zvakaratidza kuti kuwedzera kwe1000 mg / kgtributyl glycerideKudya kunogona kuwedzera zvakanyanya intestinal superoxide dismutase (SOD) chiitiko cheJian carp.

Nguva yekutumira: Jan-05-2023