Inyongera ya Tributyrin mu mafi nimirire ya crustacean

Amavuta acide aciriritse, harimo na butyrate nuburyo bukomokaho, yakoreshejwe nk'inyongera y'ibiryo kugira ngo ahindure cyangwa ahindure ingaruka mbi ziterwa n'ibikomoka ku bimera mu mafunguro y’amafi, kandi bifite ingaruka nyinshi zerekana umubiri ndetse n’ubuzima byongera imbaraga muri inyamaswa z’inyamabere n’amatungo.Tributyrin, ikomoka kuri aside ya butyric, yasuzumwe nk'inyongera mu mafunguro y’inyamaswa zororerwa, hamwe n’ibisubizo bitanga amoko menshi.Mu mafi na crustaceans, gushyiramo indyo ya tributyrine ni vuba aha kandi ntibyakozweho ubushakashatsi ariko ibisubizo byerekana ko bishobora kuba byiza cyane ku nyamaswa zo mu mazi.Ibi ni ingenzi cyane cyane ku bwoko bw’inyamanswa, indyo yazo zigomba kunozwa hagamijwe kugabanya ibiribwa by’amafi kugira ngo ibidukikije n’ubukungu birambye.Igikorwa kiriho kiranga tributyrin kandi kigaragaza ibisubizo nyamukuru byikoreshwa ryayo nkisoko yimirire ya acide butyric mu biryo byubwoko bwamazi.Intego nyamukuru ihabwa ubwoko bwubworozi bwamafi nuburyo tributyrine, nkinyongera yibiryo, ishobora kugira uruhare mugutezimbere ibimera bishingiye ku bimera.

Ijambo ryibanze

aquafeed, butyrate, acide butyric, acide ya fatty acide acide, triglyceride

1. Acide Butyric nubuzima bwo mundaInyamaswa zo mu mazi zifite ingingo zigogora, igihe gito cyo kugaburira ibiryo mu mara, kandi inyinshi muri zo ntizifite igifu.Amara afite imirimo ibiri yo gusya no kwinjiza.Amara ni ingenzi cyane ku nyamaswa zo mu mazi, bityo ikaba isabwa cyane kubikoresho byo kugaburira.Inyamaswa zo mu mazi zikenera proteine nyinshi.Umubare munini wibikoresho bya poroteyine bikomoka ku bimera birimo ibintu birwanya imirire, nk'ifunguro rya pamba rya pamba, akenshi bikoreshwa mu biryo byo mu mazi kugira ngo bisimbuze ifunguro ry’amafi, rikunda kwangirika kwa poroteyine cyangwa okiside y’ibinure, bigatuma amara yangirika mu nyamaswa zo mu mazi.Inkomoko ya poroteyine idafite ireme irashobora kugabanya cyane uburebure bwa mucosa yo mu mara, guhindagurika cyangwa no kumena ingirabuzimafatizo ya epiteliyale, kandi bikongera vacuole, ibyo ntibigabanya gusa igogorwa no kwinjiza intungamubiri z’ibiryo, ahubwo binagira ingaruka ku mikurire y’inyamaswa zo mu mazi.Kubwibyo, birihutirwa cyane kurinda inzira y amara yinyamaswa zo mumazi.Acide Butyric ni aside ngufi ya acide ikomoka kuri fermentation ya bagiteri ifata amara nka bacteri acide lactique na bifidobacteria.Acide Butyric irashobora kwinjizwa mu buryo butaziguye na selile yo mu mara, ikaba ari imwe mu nkomoko nyamukuru y'ingirabuzimafatizo zo mu nda.Irashobora guteza imbere gukwirakwira no gukura kwingirangingo zo mu gifu, kugumana ubusugire bwingirabuzimafatizo zo mu nda, kandi bikazamura inzitizi yo mu mara;Acide ya butyric yinjiye muri selile ya bagiteri, ibora mo butyrate ion na hydrogen ion.Ubwinshi bwa ioni ya hydrogène irashobora kubuza gukura kwa bagiteri zangiza nka Escherichia coli na Salmonella, mugihe bagiteri zifite akamaro nka bacteri acide lactique ziyongera cyane bitewe na aside irwanya aside, bityo bigahindura imiterere yibimera byigifu;Acide Butyric irashobora kubuza gukora no kwerekana ibintu bya porinflammatory mumitsi yo munda, bikabuza kubyutsa umuriro, kandi bikagabanya uburibwe bwo munda;Acide Butyric ifite ibikorwa byingenzi bya physiologique mubuzima bwamara.

2. Glyceryl butyrate

Acide Butyric ifite impumuro idashimishije kandi byoroshye guhindagurika, kandi biragoye kugera kumpera yinyuma y amara kugira uruhare nyuma yo kuribwa ninyamaswa, kuburyo idashobora gukoreshwa muburyo butaziguye.Glyceryl butyrate nigicuruzwa cyibinure cya acide butyric na glycerine.Acide Butyric na glycerine bihujwe na covalent bonds.Birahagaze kuva pH1-7 kugeza 230 ℃.Nyuma yo kuribwa ninyamaswa, glyceryl butyrate ntishobora kubora mu gifu, ahubwo ibora muri aside ya butyric na glycerine mu mara bitewe na lipase pancreatic lipase, irekura buhoro buhoro aside aside.Glyceryl butyrate, nk'inyongera y'ibiryo, biroroshye gukoresha, umutekano, udafite uburozi, kandi ufite uburyohe bwihariye.Ntabwo ikemura gusa ikibazo ko aside ya butyric igoye kongeramo nkamazi kandi impumuro mbi, ariko kandi inatezimbere ikibazo cyuko aside butyric igoye kugera mumara iyo ikoreshejwe muburyo butaziguye.Bifatwa nkimwe mubikomoka kuri acide butyric nziza nibicuruzwa birwanya histamine.

2.1 Glyceryl Tributyrate na Glyceryl Monobutyrate

Tributyrinigizwe na molekile 3 za acide butyric na molekile 1 ya glycerol.Tributyrin irekura buhoro buhoro aside ya butyric mu mara ikoresheje lipase pancreatic lipase, igice cyacyo kikarekurwa imbere y amara, kandi igice cyacyo gishobora kugera inyuma y amara kugirango kigire uruhare;Acide ya monobutyric glyceride ikorwa na molekile imwe ya acide butyric ihuza urubuga rwa mbere rwa glycerol (urubuga Sn-1), rufite hydrophilique na lipofilique.Irashobora kugera kumpera yinyuma y amara hamwe numutobe wigifu.Acide imwe ya butyric irekurwa na lipase pancreatic lipase, kandi zimwe zinjizwa neza na selile epithelial selile.Yangirika muri acide butyric na glycerol mu ngirangingo zo mu mara, itera gukura kwa villi yo munda.Glyceryl butyrate ifite polarike ya polarike hamwe na polarite, ishobora kwinjirira neza urukuta rwa hydrophilique cyangwa lipophilique selile ya membrane nyamukuru ya bagiteri nyamukuru itera indwara, gutera bagiteri, gusenya imiterere ya selile, no kwica bagiteri zangiza.Acide ya monobutyric glyceride igira ingaruka zikomeye za antibacterial kuri bagiteri nziza ya bagiteri na bagiteri-mbi, kandi ifite antibacterial nziza.

2.2 Gukoresha glyceryl butyrate mubicuruzwa byo mumazi

Glyceryl butyrate, nkibikomoka kuri aside ya butyric, irashobora kurekura neza aside ya butyric ikozwe na lipase yo munda yo mu nda, kandi nta mpumuro nziza, ihamye, itekanye kandi isigaye ubusa.Ni bumwe mu buryo bwiza bwo gukoresha antibiyotike kandi ikoreshwa cyane mu bworozi bw'amafi.Zhai Qiuling n'abandi.yerekanye ko iyo 100-150 mg / kg tributylglycerol ester yongewe kubiryo, igipimo cyo kwiyongera ibiro, umuvuduko wubwiyongere bwihariye, ibikorwa byimisemburo itandukanye igogora hamwe nuburebure bwa villi yo munda mbere na nyuma yo kongeramo 100 mg / kg tributylglycerol ester yashoboraga kwiyongera cyane;Tang Qifeng hamwe n’abandi bashakashatsi basanze kongeramo 1.5g / kg tributylglycerol ester ku biryo bishobora kuzamura imikorere y’imikurire ya Penaeus vannamei, kandi bikagabanya cyane umubare wa vibrio itera indwara mu mara;Jiang Yingying n'abandi.yasanze kongeramo 1g / kg ya tributyl glyceride mu biryo bishobora kongera cyane ibiro byongera ibiro bya karipi ya Allogynogenetic crucian, kugabanya coefficient yibiryo, no kongera ibikorwa bya superoxide dismutase (SOD) muri hepatopancreas;Ubushakashatsi bumwe bwerekanye ko kwiyongera kwa mg / kg 1000tributyl glycerideku ndyo ishobora kongera cyane ibikorwa byo mu mara superoxide disutase (SOD) ya Jian carp.

Igihe cyo kohereza: Mutarama-05-2023