Tlatsetso ea Tributyrin tlhapi le phepo ea crustacean

Short-chain fatty acids, ho kenyeletsoa butyrate le mefuta ea eona e nkiloeng, e 'nile ea sebelisoa e le litlatsetso tsa lijo ho khutlisa kapa ho ntlafatsa litlamorao tse mpe tse ka bang teng tsa metsoako e tsoang ho limela lijong tsa aquaculture,' me li na le litlamorao tse ngata tse bonts'itsoeng hantle tsa 'mele le bophelo bo botle. liphoofolo tse anyesang le mehlape.Tributyrin, e entsoeng ka butyric acid, e hlahlobiloe e le tlatsetso lijong tsa liphoofolo tse ruuoang, ka liphello tse tšepisang mefuta e mengata.Litlhapi le li-crustaceans, ho kenyelletsoa ha lijo tsa tributyrin ke tsa morao-rao 'me ha hoa ithutoa hanyenyane empa liphello li fana ka maikutlo a hore e ka ba molemo haholo bakeng sa liphoofolo tse phelang metsing.Sena se bohlokoa haholo bakeng sa mefuta e jang nama, eo lijo tsa eona li hlokang ho ntlafatsoa molemong oa phokotso ea lijo-thollo tsa tlhapi ho matlafatsa tikoloho le moruo oa lekala.Mosebetsi oa hona joale o khetholla tributyrin mme e fana ka liphello tsa mantlha tsa tšebeliso ea eona e le mohloli oa lijo oa butyric acid lijong tsa mefuta ea metsing.Maikutlo a mantlha a fanoe ho mefuta ea liphoofolo tsa metsing le hore na tributyrin, joalo ka tlatsetso ea phepelo, e ka kenya letsoho ho ntlafatseng li-aquafeed tse thehiloeng limela.

TMAO-AQUATICAL FEPO
Mantsoe a sehlooho
aquafeed, butyrate, butyric acid, short-chain fatty acids, triglyceride
1. Butyric acid le bophelo bo botle ba malaLiphoofolo tsa metsing li na le litho tse khutšoanyane tsa ho sila lijo, nako e khutšoanyane ea ho boloka lijo ka maleng, 'me boholo ba tsona ha li na mala.Mala a na le mesebetsi e 'meli ea ho sila le ho monya.Mala a bohlokoa haholo bakeng sa liphoofolo tse phelang metsing, kahoo a na le litlhoko tse phahameng tsa lisebelisoa tsa phepo.Liphoofolo tse phelang metsing li na le tlhoko e phahameng ea protheine.Palo e kholo ea lisebelisoa tsa protheine ea limela tse nang le lintho tse thibelang phepo e nepahetseng, joalo ka cotton rapeseed meal, hangata li sebelisoa phepelong ea metsing ho nka sebaka sa lijo tsa tlhapi, tse atisang ho senyeha ha protheine kapa mafura a oxidation, a bakang tšenyo ea mala ho liphoofolo tse phelang metsing.Mafutsana boleng protheine mohloli ka haholo fokotsa bophahamo ba intestinal mucosa, lerootho kapa esita le tšolotsoeng lisele tse epithelial, 'me eketsa vacuoles, e leng feela meedi tshilo ya dijo le absorption ea limatlafatsi tse fepa, empa hape ama kholo ea liphoofolo tse phelang metsing.Ka hona, ho potlakile haholo ho sireletsa karolo ea mala ea liphoofolo tse phelang metsing.Butyric acid ke ketane e khuts'oane ea mafura acid e nkiloeng ho belisoa ha libaktheria tse molemo ka maleng joalo ka lactic acid le bifidobacteria.Butyric acid e ka kenngoa ka ho toba ke lisele tsa epithelial tsa mala, e leng e 'ngoe ea mehloli e ka sehloohong ea matla a lisele tsa mala a epithelial.E ka khothalletsa ho ata le ho hōla ha lisele tsa mala, ho boloka botšepehi ba lisele tsa mala a mala, le ho ntlafatsa mokoallo oa mala oa mala;Ka mor'a hore asiti ea butyric e kene liseleng tsa baktheria, e senyeha ka li-ion tsa butyrate le li-ion tsa hydrogen.Maemo a phahameng a li-ion tsa haedrojene a ka thibela kholo ea libaktheria tse kotsi tse kang Escherichia coli le Salmonella, ha libaktheria tse molemo tse kang lactic acid baktheria li ata ka bongata ka lebaka la ho hanyetsa ha tsona ka acid, kahoo ho ntlafatsa sebopeho sa limela tsa tšilo ea lijo;Butyric acid e ka thibela tlhahiso le polelo ea lintlha tsa proinflammatory intestinal mucosa, e thibela ho ruruha, le ho fokotsa ho ruruha ha mala;Butyric acid e na le mesebetsi ea bohlokoa ea 'mele bophelong bo botle ba mala.

2. Glyceryl butyrate

Butyric acid e na le monko o sa thabiseng 'me e bonolo ho fetoha,' me ho thata ho fihla karolong e ka morao ea mala ho phetha karolo e itseng ka mor'a ho jeoa ke liphoofolo, kahoo e ke ke ea sebelisoa ka ho toba tlhahisong.Glyceryl butyrate ke sehlahisoa se mafura sa butyric acid le glycerin.Butyric acid le glycerin li tlanngoe ke litlamo tsa covalent.Li tsitsitse ho tloha pH1-7 ho isa ho 230 ℃.Ka mor'a ho jeoa ke liphoofolo, glyceryl butyrate ha e bole ka mpeng, empa e bola ka asiti ea butyric le glycerin ka maleng tlas'a ketso ea pancreatic lipase, butyric acid butyric acid.Glyceryl butyrate, joalo ka tlatsetso ea phepelo, e bonolo ho e sebelisa, e bolokehile, ha e na chefo, ebile e na le tatso e khethehileng.Ha e rarolle feela bothata boo asiti ea butyric e thata ho e eketsa e le mokelikeli le monko o mobe, empa hape e ntlafatsa bothata ba hore butyric acid e thata ho fihla ka mpeng ea mala ha e sebelisoa ka kotloloho.E nkoa e le e 'ngoe ea lihlahisoa tse ntle ka ho fetisisa tsa butyric acid le lihlahisoa tsa anti histamine.

CAS NO 60-01-5

2.1 Glyceryl Tributyrate le Glyceryl Monobutyrate

Tributyrine na le limolek'hule tse 3 tsa butyric acid le molek'hule e le 'ngoe ea glycerol.Tributyrin e ntša butyric acid butyric ka maleng butle-butle ka pancreatic lipase, eo karolo ea eona e lokolloang ka pele ho mala, 'me karolo ea eona e ka fihla ka morao ho mala ho phetha karolo;Monobutyric acid glyceride e thehoa ke molek'hule e le 'ngoe ea butyric acid e tlamang sebakeng sa pele sa glycerol (sebaka sa Sn-1), se nang le thepa ea hydrophilic le lipophilic.E ka fihla pheletsong e ka morao ea mala ka lero la tšilo ea lijo.Asiti e 'ngoe ea butyric e lokolloa ke pancreatic lipase,' me e 'ngoe e kenngoa ka ho toba ke lisele tsa mala a epithelial.E senyehile ka butyric acid le glycerol liseleng tsa mala a mala, ho khothaletsa kholo ea intestinal villi.Glyceryl butyrate e na le polarity ea molek'hule le nonpolarity, e ka kenang ka nepo lerako la hydrophilic kapa lipophilic cell lebota la libaktheria tse kholo tsa pathogenic, tsa hlasela lisele tsa baktheria, tsa senya sebopeho sa sele, 'me tsa bolaea libaktheria tse kotsi.Monobutyric acid glyceride e na le phello e matla ea antibacterial ho libaktheria tsa gram-positive le libaktheria tsa gram-negative, 'me e na le phello e ntle ea antibacterial.

2.2 Ho sebelisoa ha glyceryl butyrate lihlahisoa tsa metsing

Glyceryl butyrate, joalo ka derivative ea butyric acid, e ka lokolla butyric acid ka nepo tlasa ts'ebetso ea mala pancreatic lipase, 'me ha e na monko, e tsitsitse, e bolokehile ebile ha e na masala.Ke e 'ngoe ea mekhoa e metle ka ho fetisisa ea lithibela-mafu 'me e sebelisoa haholo ho aquaculture.Zhai Qiuling et al.e bontšitse hore ha 100-150 mg / kg tributylglycerol ester e kenngoa lijong, sekhahla sa boima ba 'mele, sekhahla se khethehileng sa khōlo, mesebetsi ea li-enzyme tse sa tšoaneng tsa tšilo ea lijo le bophahamo ba intestinal villi pele le ka mor'a ho eketsoa ha 100 mg / kg tributylglycerol ester e ka khona. e eketseha haholo;Tang Qifeng le bafuputsi ba bang ba fumane hore ho eketsa 1.5g / kg tributylglycerol ester ho fepa ho ka ntlafatsa haholo ts'ebetso ea kgolo ea Penaeus vannamei, le ho fokotsa haholo palo ea pathogenic vibrio ka maleng;Jiang Yingying et al.o fumane hore ho eketsa 1g / kg ea tributyl glyceride ho fepa ho ka eketsa haholo tekanyo ea boima ba 'mele ea Allogynogenetic crucian carp, ho fokotsa coefficient ea lijo, le ho eketsa mosebetsi oa superoxide dismutase (SOD) ka hepatopancreas;Liphuputso tse ling li bontšitse hore tlatsetso ea 1000 mg / kgtributyl glycerideho ja ho ka eketsa haholo ts'ebetso ea intestinal superoxide dismutase (SOD) ea Jian carp.

 


Nako ea poso: Jan-05-2023